@prefix foaf: .
@prefix wikipedia-en: .
@prefix dbr: .
wikipedia-en:Benfotiamine foaf:primaryTopic dbr:Benfotiamine .
@prefix dbo: .
dbr:Thiamine dbo:wikiPageWikiLink dbr:Benfotiamine .
dbr:Alcoholic_polyneuropathy dbo:wikiPageWikiLink dbr:Benfotiamine .
@prefix rdf: .
@prefix wikidata: .
dbr:Benfotiamine rdf:type wikidata:Q8386 .
@prefix yago: .
dbr:Benfotiamine rdf:type yago:MethaneSeries114951377 ,
yago:WikicatAmines ,
dbo:Drug ,
yago:Insecticide114919948 ,
yago:Pesticide114980215 ,
yago:Amine114739004 ,
yago:WikicatAlkenes .
@prefix ns7: .
dbr:Benfotiamine rdf:type ns7:ChemicalObject ,
yago:AliphaticCompound114601294 ,
yago:Alkene114713120 ,
yago:PhysicalEntity100001930 .
@prefix owl: .
dbr:Benfotiamine rdf:type owl:Thing .
@prefix umbel-rc: .
dbr:Benfotiamine rdf:type umbel-rc:DrugProduct ,
yago:Part113809207 ,
yago:WikicatAromaticCompounds ,
yago:WikicatNitriles ,
yago:Relation100031921 ,
yago:Nitrile114827346 ,
yago:AromaticCompound114610088 ,
yago:WikicatOrganophosphates ,
yago:Compound114818238 ,
yago:WikicatPyrimidines ,
yago:Base114618253 ,
yago:Chemical114806838 ,
yago:Substance100019613 ,
yago:Matter100020827 ,
yago:OrganicCompound114727670 ,
yago:Material114580897 ,
yago:Organophosphate114969994 ,
dbo:ChemicalSubstance ,
yago:Hydrocarbon114911057 ,
yago:Abstraction100002137 ,
yago:Pyrimidine114999913 .
@prefix rdfs: .
dbr:Benfotiamine rdfs:label "\u0411\u0435\u043D\u0444\u043E\u0442\u0438\u0430\u043C\u0438\u043D"@ru ,
"Benfotiamin"@de ,
"\u30D9\u30F3\u30D5\u30A9\u30C1\u30A2\u30DF\u30F3"@ja ,
"Benfotiamine"@en ;
rdfs:comment "Benfotiamine (rINN, or S-benzoylthiamine O-monophosphate) is a synthetic, fat-soluble, S-acyl derivative of thiamine (vitamin B1) that is approved in some countries as a medication or dietary supplement to treat diabetic sensorimotor polyneuropathy. Benfotiamine was developed in late 1950s in Japan."@en ,
"\u0411\u0435\u043D\u0444\u043E\u0442\u0438\u0430\u043C\u0438\u043D (\u043D\u043E\u0432\u043E\u043B\u0430\u0442. Benfotiamine) (S-\u0431\u0435\u043D\u0437\u043E\u0438\u043B\u0442\u0438\u0430\u043C\u0438\u043D-\u041E-\u043C\u043E\u043D\u043E\u0444\u043E\u0441\u0444\u0430\u0442) \u2014 \u0436\u0438\u0440\u043E\u0440\u0430\u0441\u0442\u0432\u043E\u0440\u0438\u043C\u044B\u0439 \u0430\u043D\u0430\u043B\u043E\u0433 \u0432\u0438\u0442\u0430\u043C\u0438\u043D\u0430 \u04121 (\u0442\u0438\u0430\u043C\u0438\u043D\u0430)."@ru ,
"\u30D9\u30F3\u30D5\u30A9\u30C1\u30A2\u30DF\u30F3\uFF08Benfotiamine\u3001\u5225\u540D\uFF1AS-benzoylthiamine O-monophosphate\uFF09\u306F\u5408\u6210\u30C1\u30A2\u30DF\u30F3\uFF08\u30D3\u30BF\u30DF\u30F3B1\uFF09\u8A98\u5C0E\u4F53\u306E\u4E00\u3064\u3002 \u30C9\u30A4\u30C4\u3067\u306F1993\u5E74\u304B\u3089\u8CA9\u58F2\u3055\u308C\u3066\u3044\u308B\u3002\u30D4\u30EA\u30C9\u30AD\u30B7\u30F3\uFF08\u30D3\u30BF\u30DF\u30F3B6\uFF09\u307E\u305F\u306F\u30B7\u30A2\u30CE\u30B3\u30D0\u30E9\u30DF\u30F3\uFF08\u30D3\u30BF\u30DF\u30F3B12\uFF09\u3068\u306E\u914D\u5408\u5264\u3082\u5B58\u5728\u3059\u308B\u3002\u5750\u9AA8\u795E\u7D4C\u75DB\u3084\u4ED6\u306E\u795E\u7D4C\u75DB\u306B\u9069\u7528\u3055\u308C\u308B\u3002 \u65E5\u672C\u3067\u3082\u6563\u5264\u3001\u9320\u5264\u306E\u307B\u304B\u3001\u30D9\u30F3\u30D5\u30A9\u30C1\u30A2\u30DF\u30F3\u30FB\u30D4\u30EA\u30C9\u30AD\u30B7\u30F3\u30FB\u30B7\u30A2\u30CE\u30B3\u30D0\u30E9\u30DF\u30F3\u914D\u5408\u30AB\u30D7\u30BB\u30EB\u30FB\u6563\u5264\u304C\u533B\u7642\u7528\u533B\u85AC\u54C1\u3068\u3057\u3066\u8CA9\u58F2\u3055\u308C\u3066\u3044\u308B\u307B\u304B\u3001100\u3092\u8D85\u3048\u308B\u4E00\u822C\u7528\u533B\u85AC\u54C1\u3084\u98F2\u6599\uFF08\u6307\u5B9A\u533B\u85AC\u90E8\u5916\u54C1\uFF09\u306B\u914D\u5408\u3055\u308C\u3066\u3044\u308B\u3002"@ja ,
"Benfotiamin ist eine fettl\u00F6sliche Vorstufe (Prodrug) des Vitamins B1 und wird im Organismus schnell zum wirksamen Vitamin B1 gespalten. Das fettl\u00F6sliche Benfotiamin unterscheidet sich vom wasserl\u00F6slichen Vitamin B1 dadurch, dass es zu einem deutlich h\u00F6heren Anteil (etwa 5- bis 7-mal so hoch) in den K\u00F6rper aufgenommen (resorbiert) wird. Aufgrund seiner hohen Bioverf\u00FCgbarkeit dient Benfotiamin sowohl der Vorbeugung als auch der Behandlung eines Vitamin-B1-Mangels."@de ;
foaf:depiction ,
.
@prefix dct: .
@prefix dbc: .
dbr:Benfotiamine dct:subject dbc:Aminopyrimidines ,
dbc:Organophosphates ,
dbc:Formamides ,
dbc:Thioesters ,
dbc:Nitriles ,
dbc:Thiamine ;
dbo:abstract "Benfotiamin ist eine fettl\u00F6sliche Vorstufe (Prodrug) des Vitamins B1 und wird im Organismus schnell zum wirksamen Vitamin B1 gespalten. Das fettl\u00F6sliche Benfotiamin unterscheidet sich vom wasserl\u00F6slichen Vitamin B1 dadurch, dass es zu einem deutlich h\u00F6heren Anteil (etwa 5- bis 7-mal so hoch) in den K\u00F6rper aufgenommen (resorbiert) wird. Aufgrund seiner hohen Bioverf\u00FCgbarkeit dient Benfotiamin sowohl der Vorbeugung als auch der Behandlung eines Vitamin-B1-Mangels."@de ,
"Benfotiamine (rINN, or S-benzoylthiamine O-monophosphate) is a synthetic, fat-soluble, S-acyl derivative of thiamine (vitamin B1) that is approved in some countries as a medication or dietary supplement to treat diabetic sensorimotor polyneuropathy. Benfotiamine was developed in late 1950s in Japan."@en ,
"\u0411\u0435\u043D\u0444\u043E\u0442\u0438\u0430\u043C\u0438\u043D (\u043D\u043E\u0432\u043E\u043B\u0430\u0442. Benfotiamine) (S-\u0431\u0435\u043D\u0437\u043E\u0438\u043B\u0442\u0438\u0430\u043C\u0438\u043D-\u041E-\u043C\u043E\u043D\u043E\u0444\u043E\u0441\u0444\u0430\u0442) \u2014 \u0436\u0438\u0440\u043E\u0440\u0430\u0441\u0442\u0432\u043E\u0440\u0438\u043C\u044B\u0439 \u0430\u043D\u0430\u043B\u043E\u0433 \u0432\u0438\u0442\u0430\u043C\u0438\u043D\u0430 \u04121 (\u0442\u0438\u0430\u043C\u0438\u043D\u0430)."@ru ,
"\u30D9\u30F3\u30D5\u30A9\u30C1\u30A2\u30DF\u30F3\uFF08Benfotiamine\u3001\u5225\u540D\uFF1AS-benzoylthiamine O-monophosphate\uFF09\u306F\u5408\u6210\u30C1\u30A2\u30DF\u30F3\uFF08\u30D3\u30BF\u30DF\u30F3B1\uFF09\u8A98\u5C0E\u4F53\u306E\u4E00\u3064\u3002 \u30C9\u30A4\u30C4\u3067\u306F1993\u5E74\u304B\u3089\u8CA9\u58F2\u3055\u308C\u3066\u3044\u308B\u3002\u30D4\u30EA\u30C9\u30AD\u30B7\u30F3\uFF08\u30D3\u30BF\u30DF\u30F3B6\uFF09\u307E\u305F\u306F\u30B7\u30A2\u30CE\u30B3\u30D0\u30E9\u30DF\u30F3\uFF08\u30D3\u30BF\u30DF\u30F3B12\uFF09\u3068\u306E\u914D\u5408\u5264\u3082\u5B58\u5728\u3059\u308B\u3002\u5750\u9AA8\u795E\u7D4C\u75DB\u3084\u4ED6\u306E\u795E\u7D4C\u75DB\u306B\u9069\u7528\u3055\u308C\u308B\u3002 \u65E5\u672C\u3067\u3082\u6563\u5264\u3001\u9320\u5264\u306E\u307B\u304B\u3001\u30D9\u30F3\u30D5\u30A9\u30C1\u30A2\u30DF\u30F3\u30FB\u30D4\u30EA\u30C9\u30AD\u30B7\u30F3\u30FB\u30B7\u30A2\u30CE\u30B3\u30D0\u30E9\u30DF\u30F3\u914D\u5408\u30AB\u30D7\u30BB\u30EB\u30FB\u6563\u5264\u304C\u533B\u7642\u7528\u533B\u85AC\u54C1\u3068\u3057\u3066\u8CA9\u58F2\u3055\u308C\u3066\u3044\u308B\u307B\u304B\u3001100\u3092\u8D85\u3048\u308B\u4E00\u822C\u7528\u533B\u85AC\u54C1\u3084\u98F2\u6599\uFF08\u6307\u5B9A\u533B\u85AC\u90E8\u5916\u54C1\uFF09\u306B\u914D\u5408\u3055\u308C\u3066\u3044\u308B\u3002"@ja ;
dbo:wikiPageWikiLink dbr:Dietary_supplement ,
dbr:International_Nonproprietary_Name ,
dbr:Thiamine ,
dbc:Aminopyrimidines ,
dbc:Thiamine ,
dbr:Thiamine_diphosphate ,
dbr:Cyanocobalamin ,
dbc:Nitriles ,
dbr:Neuropathy ,
dbr:Combination_drug ,
dbr:Metformin ,
dbr:Nephropathy ,
dbr:Over-the-counter_drug ,
dbr:Pyridoxine ,
dbr:Diabetic_neuropathy ,
dbr:Diabetic_retinopathy ,
dbc:Organophosphates ,
dbr:Thioesterase ,
,
dbc:Thioesters ,
dbr:Pharmaceutical_drug ,
dbr:Transketolase ,
dbr:Vitamin_B1_analogue ,
dbc:Formamides ,
dbr:Vitamin_B1_analogues .
@prefix dbp: .
@prefix dbt: .
dbr:Benfotiamine dbp:wikiPageUsesTemplate dbt:Stdinchicite ,
,
dbt:Vitamins ,
dbt:Cascite ,
dbt:Chemspidercite ,
dbt:Neuropathic_pain_and_fibromyalgia_pharmacotherapies ,
dbt:Fdacite ,
dbt:Drugbox ,
dbt:Ebicite ,
dbt:Short_description ,
dbt:Reflist ;
dbo:thumbnail ;
dbo:wikiPageRevisionID 1119664837 .
@prefix xsd: .
dbr:Benfotiamine dbo:wikiPageLength "9305"^^xsd:nonNegativeInteger ;
dbo:wikiPageID 9791224 ;
owl:sameAs ,
dbr:Benfotiamine ,
,
.
@prefix dbpedia-sh: .
dbr:Benfotiamine owl:sameAs dbpedia-sh:Benfotiamin ,
.
@prefix dbpedia-fi: .
dbr:Benfotiamine owl:sameAs dbpedia-fi:Benfotiamiini .
@prefix yago-res: .
dbr:Benfotiamine owl:sameAs yago-res:Benfotiamine ,
.
@prefix dbpedia-sr: .
dbr:Benfotiamine owl:sameAs dbpedia-sr:Benfotiamin ,
wikidata:Q409953 .
@prefix dbpedia-de: .
dbr:Benfotiamine owl:sameAs dbpedia-de:Benfotiamin .
@prefix gold: .
dbr:Benfotiamine gold:hypernym dbr:Derivative .
@prefix prov: .
dbr:Benfotiamine prov:wasDerivedFrom ;
foaf:isPrimaryTopicOf wikipedia-en:Benfotiamine ;
dbp:chembl 1491875 ;
dbo:chEMBL "1491875" ;
dbp:atcSuffix "DA03"@en ;
dbp:verifiedfields "changed"@en ;
dbo:alternativeName "Milgamma"@en ;
dbp:s 1 ;
dbp:n 4 ;
dbp:chemspiderid 2297665 ;
dbp:c 19 ;
dbp:verifiedrevid 449055379 ;
dbp:h 23 ;
dbo:pubchem "3032771" ;
dbp:routesOfAdministration "Oral"@en ;
dbp:o 6 ;
dbp:pubchem 3032771 ;
dbp:stdinchikey "BTNNPSLJPBRMLZ-LGMDPLHJSA-N"@en ;
dbp:smiles "O=POCCC=CC"@en ;
dbp:watchedfields "changed"@en ;
dbo:fdaUniiCode "Y92OUS2H9B" ;
dbp:iupacName "S-[2-{[methyl] amino}-5-pent-2-en-3-yl] benzenecarbothioate"@en ;
dbp:unii "Y92OUS2H9B"@en ;
dbp:casNumber 22457 ;
dbp:atcPrefix "A11"@en ;
dbp:stdinchi 1 ;
dbo:casNumber "22457-89-2" ;
dbp:p 1 ;
dbo:chEBI "41039" ;
dbp:chebi 41039 ;
dbp:legalStatus "OTC"@en ;
dbp:synonyms "(S-Benzoylthiamine O-monophosphate)"@en ;
dbp:image "Benfotiamine ball-and-stick.png"@en ;
dbp:tradename "Milgamma"@en .
dbr:ATC_code_A11 dbo:wikiPageWikiLink dbr:Benfotiamine .
dbr:Vitamin_B1_analogues dbo:wikiPageWikiLink dbr:Benfotiamine .
dbr:Neuropathic_pain dbo:wikiPageWikiLink dbr:Benfotiamine .
dbr:Advanced_glycation_end-product dbo:wikiPageWikiLink dbr:Benfotiamine .
@prefix ns23: .
ns23:_Be dbo:wikiPageWikiLink dbr:Benfotiamine .
dbr:Heme_oxygenase dbo:wikiPageWikiLink dbr:Benfotiamine .
dbr:Glyoxalase_system dbo:wikiPageWikiLink dbr:Benfotiamine .
dbr:Benfothiamine dbo:wikiPageWikiLink dbr:Benfotiamine ;
dbo:wikiPageRedirects dbr:Benfotiamine .
dbr:C19H23N4O6PS dbo:wikiPageWikiLink dbr:Benfotiamine ;
dbo:wikiPageRedirects dbr:Benfotiamine .
dbo:wikiPageWikiLink dbr:Benfotiamine .
dbr:ATC_code_A11DA03 dbo:wikiPageWikiLink dbr:Benfotiamine ;
dbo:wikiPageRedirects dbr:Benfotiamine .
dbr:ATCvet_code_QA11DA03 dbo:wikiPageWikiLink dbr:Benfotiamine ;
dbo:wikiPageRedirects dbr:Benfotiamine .
dbr:Milgamma dbo:wikiPageWikiLink dbr:Benfotiamine ;
dbo:wikiPageRedirects dbr:Benfotiamine .
dbr:Benfotiamin dbo:wikiPageWikiLink dbr:Benfotiamine ;
dbo:wikiPageRedirects dbr:Benfotiamine .
dbr:NeuRemedy dbo:wikiPageWikiLink dbr:Benfotiamine ;
dbo:wikiPageRedirects dbr:Benfotiamine .