@prefix dbo: . @prefix dbr: . dbr:List_of_human_clusters_of_differentiation dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Cadherin-2 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CX3CR1 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:HEPACAM dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:P-selectin_glycoprotein_ligand-1 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:PVSRIPO dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . @prefix foaf: . @prefix wikipedia-en: . wikipedia-en:Cell_adhesion_molecule foaf:primaryTopic dbr:Cell_adhesion_molecule . dbr:Cytokine dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CD44 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:KLF2 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Sialoadhesin dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Index_of_biophysics_articles dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Angiogenesis_inhibitor dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Selectin dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:DSCAM dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Keratin_5 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Extracellular_polymeric_substance dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:L-selectin dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CD2 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Gut-specific_homing dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Interleukin_19 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Chemokine_receptor dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CD58 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Immunomodulatory_imide_drug dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Lymphotoxin dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Auditory_processing_disorder dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:VCAM-1 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CD164 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CDON dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CHL1 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CNTNAP2 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Soluble_cell_adhesion_molecules dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:NFASC dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Peripherin_2 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:ITGAE dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Autism_spectrum dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Integral_membrane_protein dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:P-selectin dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Follicular_lymphoma dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Epoxyeicosatrienoic_acid dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Natalizumab dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Cell_adhesion_molecules dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule ; dbo:wikiPageRedirects dbr:Cell_adhesion_molecule . dbr:Minocycline dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:L1_family dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Membrane_protein dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:CD24 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:GLYCAM1 dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Generalized_epilepsy_with_febrile_seizures_plus dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . dbr:Proerythroblast dbo:wikiPageWikiLink dbr:Cell_adhesion_molecule . @prefix rdf: . @prefix yago: . dbr:Cell_adhesion_molecule rdf:type yago:PhysicalEntity100001930 , yago:Part113809207 , dbo:Protein , yago:Matter100020827 , yago:Protein114728724 , yago:OrganicCompound114727670 , yago:Material114580897 , yago:Macromolecule114944888 , yago:WikicatProteins , yago:Relation100031921 , yago:Molecule114682133 , yago:Unit109465459 , yago:Compound114818238 , yago:Chemical114806838 , yago:Substance100019613 , yago:WikicatCellAdhesionProteins , yago:Thing100002452 , yago:Glycoprotein114888310 , yago:ConjugatedProtein114731135 , yago:Abstraction100002137 , yago:WikicatGlycoproteins . @prefix rdfs: . dbr:Cell_adhesion_molecule rdfs:label "Zelladh\u00E4sionsmolek\u00FCl"@de , "\u7D30\u80DE\u63A5\u7740\u5206\u5B50"@ja , "\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50"@zh , "Mol\u00E9cula de adhesi\u00F3n celular"@es , "Cell adhesion molecule"@en , "Molecole di adesione"@it , "Atxikipen molekula"@eu , "Celadhesiemoleculen"@nl , "Prot\u00E9ine d'adh\u00E9sion cellulaire"@fr , "Mol\u00E8cula d'adhesi\u00F3 cel\u00B7lular"@ca , "Mol\u00E9cula de ades\u00E3o celular"@pt , "\u041C\u043E\u043B\u0435\u043A\u0443\u043B\u044B \u043A\u043B\u0435\u0442\u043E\u0447\u043D\u043E\u0439 \u0430\u0434\u0433\u0435\u0437\u0438\u0438"@ru ; rdfs:comment "Les prot\u00E9ines d'adh\u00E9sion cellulaire (ou CAM, acronyme de l'anglais cell adhesion molecule, signifiant \u00AB mol\u00E9cule d'adh\u00E9sion cellulaire \u00BB) sont des prot\u00E9ines intervenant dans les m\u00E9canismes de liaison cellulaire. Elles font partie de la superfamille des immunoglobulines."@fr , "Zelladh\u00E4sionsmolek\u00FCle (auch CAMs, englisch cell adhesion molecule) sind eine Klasse von Proteinen, die die Kontakte zwischen Zellen in einem tierischen Gewebe vermitteln. Sie haben zwei grundlegende Funktionen: \n* den Zusammenhalt von Geweben und \n* die Kommunikation von Zellen miteinander zu erm\u00F6glichen. Es handelt sich um integrale Membranproteine, die aus der Zelle herausragen und auf der Zelloberfl\u00E4che mit anderen Proteinen in Wechselwirkung treten."@de , "\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50\uFF08\u82F1\u8A9E\uFF1ACell adhesion molecules\uFF0C\u7F29\u5199\uFF1ACAMs\uFF09\u662F\u4F4D\u4E8E\u7EC6\u80DE\u8868\u9762\u4E0A\u7684\u86CB\u767D\uFF0C\u53C2\u4E0E\u4E86\u4E0E\u5176\u4ED6\u7EC6\u80DE\u6216\u7EC6\u80DE\u5916\u57FA\u8D28\uFF08ECM\uFF09\u4E2D\u7684\u79F0\u4E3A\u7684\u904E\u7A0B\u3002\u5728\u672C\u8D28\u4E0A\uFF0C\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50\u5E2E\u52A9\u7EC6\u80DE\u5F7C\u6B64\u9ECF\u9644\u548C\u5176\u5468\u56F4\u73AF\u5883\u7684\u9ECF\u9644\u3002 \u8FD9\u4E9B\u86CB\u767D\u8D28\u901A\u5E38\u662F\u8DE8\u819C\u86CB\u767D\uFF0C\u662F\u7531\u4E09\u4E2A\u9886\u57DF\u7EC4\u6210\uFF1A\u5728\u7EC6\u80DE\u5185\u9886\u57DF\u4E0E\u7EC6\u80DE\u9AA8\u67B6\u7684\u7684\u76F8\u4E92\u4F5C\u7528\uFF0C\u5728\u8DE8\u819C\u9886\u57DF(\u7EC6\u80DE\u8868\u9762)\u7684\uFF0C\u548C\u5728\u7EC6\u80DE\u5916\u9886\u57DF\u7684\u76F8\u4E92\u4F5C\u7528\uFF0C\u6216\u8005\u4E0E\u76F8\u540C\u7C7B\u578B\u7684\u5176\u4ED6\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50\uFF08\u55DC\u540C\u6027\u7ED3\u5408\uFF09\u6216\u8005\u4E0E\u5176\u4ED6\u7684\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50\u6216\u7EC6\u80DE\u5916\u57FA\u8D28\uFF08\u55DC\u5F02\u6027\u7ED3\u5408\uFF09\u7684\u76F8\u4E92\u4F5C\u7528\u3002"@zh , "Atxikipen molekulak zelula mintzean aurkitzen diren etaatxikipen zelularrean zelula-zelula edo zelula-matrize estrazelularraren arteko loturan parten hartzen duten molekulak dira. Ingelesez CAM (Cell Adhesion Molecules) bezala ezagutzen dira."@eu , "Las mol\u00E9culas de adhesi\u00F3n celular (MAC) son glucoprote\u00EDnas que se encuentran en la superficie de la mayor\u00EDa de las c\u00E9lulas, mediante la adhesi\u00F3n celular c\u00E9lula a c\u00E9lula o la adhesi\u00F3n de la c\u00E9lula con la matriz extracelular. Por ser receptores fluct\u00FAan entre estados de alta y baja afinidad con sus respectivos ligandos, los que tienen caracter\u00EDsticas de especificad para cada mol\u00E9cula de adhesi\u00F3n. Las mol\u00E9culas de adhesi\u00F3n comprende cuatro grandes familias: a. Receptores de la familia de integrinas. b. Receptores de la superfamilia de inmunoglobulinas. c. Receptores de la familia de las selectinas."@es , "Celadhesiemoleculen zijn eiwitten aan het oppervlak van cellen die een rol spelen bij celadhesie, ofwel de binding met andere cellen of met de extracellulaire matrix. Deze eiwitten zijn transmembraanreceptoren. Ze bestaan uit drie gebieden: een intracellulair gebied dat een interactie aangaat met het cytoskelet, een transmembraangebied en een extracellulair gebied dat een interactie aangaat met andere celadhesiemoleculen van dezelfde soort (homofiele binding) of een andere soort (heterofiele binding)."@nl , "\u041C\u043E\u043B\u0435\u043A\u0443\u043B\u044B \u043A\u043B\u0435\u0442\u043E\u0447\u043D\u043E\u0439 \u0430\u0434\u0433\u0435\u0437\u0438\u0438 \u2014 \u043C\u0435\u043C\u0431\u0440\u0430\u043D\u043D\u044B\u0435 \u0431\u0435\u043B\u043A\u0438, \u0443\u0447\u0430\u0441\u0442\u0432\u0443\u044E\u0449\u0438\u0435 \u0432 \u0441\u0432\u044F\u0437\u044B\u0432\u0430\u043D\u0438\u0438 \u043A\u043B\u0435\u0442\u043A\u0438 \u0441 \u0432\u043D\u0435\u043A\u043B\u0435\u0442\u043E\u0447\u043D\u044B\u043C \u043C\u0430\u0442\u0440\u0438\u043A\u0441\u043E\u043C \u0438 \u0434\u0440\u0443\u0433\u0438\u043C\u0438 \u043A\u043B\u0435\u0442\u043A\u0430\u043C\u0438. \u0411\u043E\u043B\u044C\u0448\u0438\u043D\u0441\u0442\u0432\u043E \u043C\u043E\u043B\u0435\u043A\u0443\u043B \u043A\u043B\u0435\u0442\u043E\u0447\u043D\u043E\u0439 \u0430\u0434\u0433\u0435\u0437\u0438\u0438 \u043F\u0440\u0438\u043D\u0430\u0434\u043B\u0435\u0436\u0430\u0442 \u043A \u043F\u044F\u0442\u0438 \u0441\u0435\u043C\u0435\u0439\u0441\u0442\u0432\u0430\u043C \u0431\u0435\u043B\u043A\u043E\u0432: \n* \u0418\u043D\u0442\u0435\u0433\u0440\u0438\u043D\u044B \n* \u0410\u0434\u0433\u0435\u0437\u0438\u0432\u043D\u044B\u0435 \u0440\u0435\u0446\u0435\u043F\u0442\u043E\u0440\u044B \n* \u0421\u0435\u043B\u0435\u043A\u0442\u0438\u043D\u044B \n* \u041A\u0430\u0434\u0433\u0435\u0440\u0438\u043D\u044B \n* ."@ru , "\u7D30\u80DE\u63A5\u7740\u5206\u5B50\uFF08\u3055\u3044\u307C\u3046\u305B\u3063\u3061\u3083\u304F\u3076\u3093\u3057\u3001\u82F1: cell adhesion molecules\u3001\u7565\u79F0\uFF1ACAMs\uFF09\u306F\u3001\u7D30\u80DE\u63A5\u7740\u3092\u62C5\u3046\u5206\u5B50\u306E\u7DCF\u79F0\u3067\u3042\u308B\u3002\u591A\u7D30\u80DE\u751F\u7269\u306E\u5B9F\u9A13\u52D5\u7269\u3067\u3082\u3042\u308B\u30DE\u30A6\u30B9\u30FB\u30E9\u30C3\u30C8\u3001\u30CB\u30EF\u30C8\u30EA\u3001\u30B7\u30E7\u30A6\u30B8\u30E7\u30A6\u30D0\u30A8\u3001\u7DDA\u866B\u3001\u30BC\u30D6\u30E9\u30D5\u30A3\u30C3\u30B7\u30E5\u306A\u3069\u3068\u3001\u57F9\u990A\u7D30\u80DE\u3084\u30D2\u30C8\u3092\u4E2D\u5FC3\u306B\u7814\u7A76\u3055\u308C\u3001\u767A\u898B\u3055\u308C\u305F\u3002\u5206\u5B50\u306E\u5B9F\u4F53\u306F\u3001\u4E3B\u306B\u305D\u306E\u751F\u7269\u304C\u5408\u6210\u3059\u308B\u30BF\u30F3\u30D1\u30AF\u8CEA\uFF08\u9AD8\u5206\u5B50\uFF09\u3067\u3001\u30D5\u30A1\u30DF\u30EA\u30FC\u3084\u30A2\u30A4\u30BD\u30D5\u30A9\u30FC\u30E0\u3092\u542B\u3081\u308B\u3068\u6570\u767E\u7A2E\u985E\u306B\u53CA\u3076\u30BF\u30F3\u30D1\u30AF\u8CEA\u6027\u306E\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u304C\u767A\u898B\u3055\u308C\u3066\u3044\u308B\u3002\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u306E\uFF08\u6A21\u9020\u54C1\uFF09\u306E\u6709\u6A5F\u5408\u6210\u5316\u5408\u7269\u3084\u7D44\u307F\u63DB\u3048DNA\u7523\u7269\u306F\u3001\u8003\u3048\u65B9\u306B\u3082\u3088\u308B\u304C\u3001\u4EBA\u5DE5\u7684\u306A\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u3068\u307F\u306A\u3059\u4EBA\u304C\u591A\u3044\u3002\u975E\u751F\u7269\u306E\u5408\u6210\u9AD8\u5206\u5B50\u306A\u3069\u306B\u3082\u7D30\u80DE\u63A5\u7740\u3092\u3059\u308B\u7269\u8CEA\u304C\u3042\u308B\u3002 \u300C\u7D30\u80DE\u63A5\u7740\u300D\u3082\u53C2\u7167 \u751F\u7269\u304C\u5408\u6210\u3059\u308B\u4F4E\u5206\u5B50\u6709\u6A5F\u5316\u5408\u7269\u3001\u6709\u6A5F\u5408\u6210\u5316\u5408\u7269\u3001\u7121\u6A5F\u5316\u5408\u7269\u306B\u3082\u7D30\u80DE\u306B\u63A5\u7740\u3059\u308B\u5206\u5B50\u306F\u3042\u308B\u304C\u3001\u4E00\u822C\u7684\u306B\u306F\u3001\u3053\u308C\u3089\u306F\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u306E\u7BC4\u7587\u306B\u5165\u308C\u306A\u3044\u3002 \u7D30\u80DE\u63A5\u7740\u5206\u5B50\u306F\u3001\u30D5\u30A1\u30DF\u30EA\u30FC\u3084\u30A2\u30A4\u30BD\u30D5\u30A9\u30FC\u30E0\u3092\u542B\u3081\u308B\u3068\u6570\u767E\u7A2E\u985E\u306B\u304A\u3088\u3076\u305F\u3081\u3001\u3053\u3053\u3067\u306F\u3001\u30D5\u30A1\u30DF\u30EA\u30FC\u3084\u30A2\u30A4\u30BD\u30D5\u30A9\u30FC\u30E0\u306F\u4EE3\u8868\u5206\u5B50\u3092\u793A\u3057\u305F\u3002"@ja , "Le molecole di adesione (o CAM, dall'inglese \"Cell Adhesion Molecule\") sono proteine collocate sulla superficie cellulare coinvolte nel legame con altre cellule o con la matrice extracellulare. Le CAM sono principalmente recettori transmembrana composti da tre domini: \n* intracellulare, che interagisce con il citoscheletro; \n* transmembrana; \n* extracellulare, che interagisce con altre molecole di adesione dello stesso tipo (legame omofilo), di altro tipo o con la matrice extracellulare (legame eterofilo)."@it , "Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each other and to their surroundings. CAMs are crucial components in maintaining tissue structure and function. In fully developed animals, these molecules play an integral role in generating force and movement and consequently ensuring that organs are able to execute their functions normally. In addition to serving as \"molecular glue\", CAMs play important roles in the cellular mechanisms of growth, contact inhibition, and apoptosis. Aberrant expression of CAMs may result in a wide range of pathologies, ranging from frostbite to cancer."@en , "Les mol\u00E8cules d'adhesi\u00F3 cel\u00B7lular (MAC) s\u00F3n prote\u00EFnes localitzades en la superf\u00EDcie cel\u00B7lular, implicades en la uni\u00F3 amb altres c\u00E8l\u00B7lules amb la matriu extracel\u00B7lular en el proc\u00E9s anomenat adhesi\u00F3 cel\u00B7lular."@ca , "As mol\u00E9culas de ades\u00E3o celular ou CAM's s\u00E3o mol\u00E9culas que permitem a liga\u00E7\u00E3o entre as c\u00E9lulas ou entre c\u00E9lulas e a matriz extracelular."@pt . @prefix dcterms: . @prefix dbc: . dbr:Cell_adhesion_molecule dcterms:subject dbc:Cell_adhesion_molecules , dbc:Single-pass_transmembrane_proteins ; dbo:abstract "Le molecole di adesione (o CAM, dall'inglese \"Cell Adhesion Molecule\") sono proteine collocate sulla superficie cellulare coinvolte nel legame con altre cellule o con la matrice extracellulare. Le CAM sono principalmente recettori transmembrana composti da tre domini: \n* intracellulare, che interagisce con il citoscheletro; \n* transmembrana; \n* extracellulare, che interagisce con altre molecole di adesione dello stesso tipo (legame omofilo), di altro tipo o con la matrice extracellulare (legame eterofilo). A seconda della densit\u00E0 di proteine, e quindi di contatti tra il metaplasma e la cellula, si pu\u00F2 parlare di contatti focali, emidesmosomi, ."@it , "\u041C\u043E\u043B\u0435\u043A\u0443\u043B\u044B \u043A\u043B\u0435\u0442\u043E\u0447\u043D\u043E\u0439 \u0430\u0434\u0433\u0435\u0437\u0438\u0438 \u2014 \u043C\u0435\u043C\u0431\u0440\u0430\u043D\u043D\u044B\u0435 \u0431\u0435\u043B\u043A\u0438, \u0443\u0447\u0430\u0441\u0442\u0432\u0443\u044E\u0449\u0438\u0435 \u0432 \u0441\u0432\u044F\u0437\u044B\u0432\u0430\u043D\u0438\u0438 \u043A\u043B\u0435\u0442\u043A\u0438 \u0441 \u0432\u043D\u0435\u043A\u043B\u0435\u0442\u043E\u0447\u043D\u044B\u043C \u043C\u0430\u0442\u0440\u0438\u043A\u0441\u043E\u043C \u0438 \u0434\u0440\u0443\u0433\u0438\u043C\u0438 \u043A\u043B\u0435\u0442\u043A\u0430\u043C\u0438. \u0411\u043E\u043B\u044C\u0448\u0438\u043D\u0441\u0442\u0432\u043E \u043C\u043E\u043B\u0435\u043A\u0443\u043B \u043A\u043B\u0435\u0442\u043E\u0447\u043D\u043E\u0439 \u0430\u0434\u0433\u0435\u0437\u0438\u0438 \u043F\u0440\u0438\u043D\u0430\u0434\u043B\u0435\u0436\u0430\u0442 \u043A \u043F\u044F\u0442\u0438 \u0441\u0435\u043C\u0435\u0439\u0441\u0442\u0432\u0430\u043C \u0431\u0435\u043B\u043A\u043E\u0432: \n* \u0418\u043D\u0442\u0435\u0433\u0440\u0438\u043D\u044B \n* \u0410\u0434\u0433\u0435\u0437\u0438\u0432\u043D\u044B\u0435 \u0440\u0435\u0446\u0435\u043F\u0442\u043E\u0440\u044B \n* \u0421\u0435\u043B\u0435\u043A\u0442\u0438\u043D\u044B \n* \u041A\u0430\u0434\u0433\u0435\u0440\u0438\u043D\u044B \n* ."@ru , "Celadhesiemoleculen zijn eiwitten aan het oppervlak van cellen die een rol spelen bij celadhesie, ofwel de binding met andere cellen of met de extracellulaire matrix. Deze eiwitten zijn transmembraanreceptoren. Ze bestaan uit drie gebieden: een intracellulair gebied dat een interactie aangaat met het cytoskelet, een transmembraangebied en een extracellulair gebied dat een interactie aangaat met andere celadhesiemoleculen van dezelfde soort (homofiele binding) of een andere soort (heterofiele binding)."@nl , "As mol\u00E9culas de ades\u00E3o celular ou CAM's s\u00E3o mol\u00E9culas que permitem a liga\u00E7\u00E3o entre as c\u00E9lulas ou entre c\u00E9lulas e a matriz extracelular."@pt , "Las mol\u00E9culas de adhesi\u00F3n celular (MAC) son glucoprote\u00EDnas que se encuentran en la superficie de la mayor\u00EDa de las c\u00E9lulas, mediante la adhesi\u00F3n celular c\u00E9lula a c\u00E9lula o la adhesi\u00F3n de la c\u00E9lula con la matriz extracelular. Por ser receptores fluct\u00FAan entre estados de alta y baja afinidad con sus respectivos ligandos, los que tienen caracter\u00EDsticas de especificad para cada mol\u00E9cula de adhesi\u00F3n. Todas las mol\u00E9culas estructuralmente tienen un dominio extracelular, un dominio transmembrana, y un dominio intracelular. El dominio extracelular en ciertas mol\u00E9culas se desprende de la c\u00E9lula y se solubiliza en el suero, como en el caso de las selectinas. Las mol\u00E9culas de adhesi\u00F3n al unirse a su ligando o receptor espec\u00EDfico, producen un cambio conformacional en el dominio extracelular que afecta la funci\u00F3n de las c\u00E9lulas, produciendo cambios intracelulares en el citoesqueleto o en su composici\u00F3n qu\u00EDmica. Esto puede ocurrir como una respuesta fisiol\u00F3gica o una respuesta patol\u00F3gica. Las mol\u00E9culas de adhesi\u00F3n adem\u00E1s est\u00E1n involucradas en la embriog\u00E9nesis, crecimiento celular, diferenciaci\u00F3n celular... etc. Las mol\u00E9culas de adhesi\u00F3n comprende cuatro grandes familias: a. Receptores de la familia de integrinas. b. Receptores de la superfamilia de inmunoglobulinas. c. Receptores de la familia de las selectinas. d. Receptores de la familia de las cadherinas. Algunos autores consideran que son seis familias e incluyen a los receptores del \u00E1cido hialur\u00F3nico o isoformas de CD44 y a los receptores de la prote\u00EDna tirosinfosfatasa3-4."@es , "\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50\uFF08\u82F1\u8A9E\uFF1ACell adhesion molecules\uFF0C\u7F29\u5199\uFF1ACAMs\uFF09\u662F\u4F4D\u4E8E\u7EC6\u80DE\u8868\u9762\u4E0A\u7684\u86CB\u767D\uFF0C\u53C2\u4E0E\u4E86\u4E0E\u5176\u4ED6\u7EC6\u80DE\u6216\u7EC6\u80DE\u5916\u57FA\u8D28\uFF08ECM\uFF09\u4E2D\u7684\u79F0\u4E3A\u7684\u904E\u7A0B\u3002\u5728\u672C\u8D28\u4E0A\uFF0C\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50\u5E2E\u52A9\u7EC6\u80DE\u5F7C\u6B64\u9ECF\u9644\u548C\u5176\u5468\u56F4\u73AF\u5883\u7684\u9ECF\u9644\u3002 \u8FD9\u4E9B\u86CB\u767D\u8D28\u901A\u5E38\u662F\u8DE8\u819C\u86CB\u767D\uFF0C\u662F\u7531\u4E09\u4E2A\u9886\u57DF\u7EC4\u6210\uFF1A\u5728\u7EC6\u80DE\u5185\u9886\u57DF\u4E0E\u7EC6\u80DE\u9AA8\u67B6\u7684\u7684\u76F8\u4E92\u4F5C\u7528\uFF0C\u5728\u8DE8\u819C\u9886\u57DF(\u7EC6\u80DE\u8868\u9762)\u7684\uFF0C\u548C\u5728\u7EC6\u80DE\u5916\u9886\u57DF\u7684\u76F8\u4E92\u4F5C\u7528\uFF0C\u6216\u8005\u4E0E\u76F8\u540C\u7C7B\u578B\u7684\u5176\u4ED6\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50\uFF08\u55DC\u540C\u6027\u7ED3\u5408\uFF09\u6216\u8005\u4E0E\u5176\u4ED6\u7684\u7EC6\u80DE\u9ECF\u9644\u5206\u5B50\u6216\u7EC6\u80DE\u5916\u57FA\u8D28\uFF08\u55DC\u5F02\u6027\u7ED3\u5408\uFF09\u7684\u76F8\u4E92\u4F5C\u7528\u3002"@zh , "Les mol\u00E8cules d'adhesi\u00F3 cel\u00B7lular (MAC) s\u00F3n prote\u00EFnes localitzades en la superf\u00EDcie cel\u00B7lular, implicades en la uni\u00F3 amb altres c\u00E8l\u00B7lules amb la matriu extracel\u00B7lular en el proc\u00E9s anomenat adhesi\u00F3 cel\u00B7lular."@ca , "Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each other and to their surroundings. CAMs are crucial components in maintaining tissue structure and function. In fully developed animals, these molecules play an integral role in generating force and movement and consequently ensuring that organs are able to execute their functions normally. In addition to serving as \"molecular glue\", CAMs play important roles in the cellular mechanisms of growth, contact inhibition, and apoptosis. Aberrant expression of CAMs may result in a wide range of pathologies, ranging from frostbite to cancer."@en , "Les prot\u00E9ines d'adh\u00E9sion cellulaire (ou CAM, acronyme de l'anglais cell adhesion molecule, signifiant \u00AB mol\u00E9cule d'adh\u00E9sion cellulaire \u00BB) sont des prot\u00E9ines intervenant dans les m\u00E9canismes de liaison cellulaire. Elles font partie de la superfamille des immunoglobulines."@fr , "Zelladh\u00E4sionsmolek\u00FCle (auch CAMs, englisch cell adhesion molecule) sind eine Klasse von Proteinen, die die Kontakte zwischen Zellen in einem tierischen Gewebe vermitteln. Sie haben zwei grundlegende Funktionen: \n* den Zusammenhalt von Geweben und \n* die Kommunikation von Zellen miteinander zu erm\u00F6glichen. Es handelt sich um integrale Membranproteine, die aus der Zelle herausragen und auf der Zelloberfl\u00E4che mit anderen Proteinen in Wechselwirkung treten."@de , "\u7D30\u80DE\u63A5\u7740\u5206\u5B50\uFF08\u3055\u3044\u307C\u3046\u305B\u3063\u3061\u3083\u304F\u3076\u3093\u3057\u3001\u82F1: cell adhesion molecules\u3001\u7565\u79F0\uFF1ACAMs\uFF09\u306F\u3001\u7D30\u80DE\u63A5\u7740\u3092\u62C5\u3046\u5206\u5B50\u306E\u7DCF\u79F0\u3067\u3042\u308B\u3002\u591A\u7D30\u80DE\u751F\u7269\u306E\u5B9F\u9A13\u52D5\u7269\u3067\u3082\u3042\u308B\u30DE\u30A6\u30B9\u30FB\u30E9\u30C3\u30C8\u3001\u30CB\u30EF\u30C8\u30EA\u3001\u30B7\u30E7\u30A6\u30B8\u30E7\u30A6\u30D0\u30A8\u3001\u7DDA\u866B\u3001\u30BC\u30D6\u30E9\u30D5\u30A3\u30C3\u30B7\u30E5\u306A\u3069\u3068\u3001\u57F9\u990A\u7D30\u80DE\u3084\u30D2\u30C8\u3092\u4E2D\u5FC3\u306B\u7814\u7A76\u3055\u308C\u3001\u767A\u898B\u3055\u308C\u305F\u3002\u5206\u5B50\u306E\u5B9F\u4F53\u306F\u3001\u4E3B\u306B\u305D\u306E\u751F\u7269\u304C\u5408\u6210\u3059\u308B\u30BF\u30F3\u30D1\u30AF\u8CEA\uFF08\u9AD8\u5206\u5B50\uFF09\u3067\u3001\u30D5\u30A1\u30DF\u30EA\u30FC\u3084\u30A2\u30A4\u30BD\u30D5\u30A9\u30FC\u30E0\u3092\u542B\u3081\u308B\u3068\u6570\u767E\u7A2E\u985E\u306B\u53CA\u3076\u30BF\u30F3\u30D1\u30AF\u8CEA\u6027\u306E\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u304C\u767A\u898B\u3055\u308C\u3066\u3044\u308B\u3002\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u306E\uFF08\u6A21\u9020\u54C1\uFF09\u306E\u6709\u6A5F\u5408\u6210\u5316\u5408\u7269\u3084\u7D44\u307F\u63DB\u3048DNA\u7523\u7269\u306F\u3001\u8003\u3048\u65B9\u306B\u3082\u3088\u308B\u304C\u3001\u4EBA\u5DE5\u7684\u306A\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u3068\u307F\u306A\u3059\u4EBA\u304C\u591A\u3044\u3002\u975E\u751F\u7269\u306E\u5408\u6210\u9AD8\u5206\u5B50\u306A\u3069\u306B\u3082\u7D30\u80DE\u63A5\u7740\u3092\u3059\u308B\u7269\u8CEA\u304C\u3042\u308B\u3002 \u300C\u7D30\u80DE\u63A5\u7740\u300D\u3082\u53C2\u7167 \u751F\u7269\u304C\u5408\u6210\u3059\u308B\u4F4E\u5206\u5B50\u6709\u6A5F\u5316\u5408\u7269\u3001\u6709\u6A5F\u5408\u6210\u5316\u5408\u7269\u3001\u7121\u6A5F\u5316\u5408\u7269\u306B\u3082\u7D30\u80DE\u306B\u63A5\u7740\u3059\u308B\u5206\u5B50\u306F\u3042\u308B\u304C\u3001\u4E00\u822C\u7684\u306B\u306F\u3001\u3053\u308C\u3089\u306F\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u306E\u7BC4\u7587\u306B\u5165\u308C\u306A\u3044\u3002 \u7D30\u80DE\u306F\u3001\u7D30\u80DE\u63A5\u7740\u90E8\u4F4D\u3067\u7D30\u80DE\u8868\u9762\u306B\u7D30\u80DE\u63A5\u7740\u88C5\u7F6E\u3092\u4F5C\u308B\u3002\u7D30\u80DE\u63A5\u7740\u88C5\u7F6E\u306F\u30011.\u7D30\u80DE\u5916\u30BF\u30F3\u30D1\u30AF\u8CEA\u30012.\u7D30\u80DE\u819C\u30BF\u30F3\u30D1\u30AF\u8CEA\u30013.\u7D30\u80DE\u819C\u88CF\u6253\u3061\u30BF\u30F3\u30D1\u30AF\u8CEA\uFF08\u7D30\u80DE\u8CEA\u5185\u306B\u63A5\u7740\u88C5\u7F6E\u3092\u652F\u3048\u308B\uFF09\u30014.\u7D30\u80DE\u5185\u30B7\u30B0\u30CA\u30EB\u4F1D\u9054\u30BF\u30F3\u30D1\u30AF\u8CEA\uFF08\u542B\u30FB\u30A2\u30C0\u30D7\u30BF\u30FC\u30BF\u30F3\u30D1\u30AF\u8CEA\uFF09\u30015.\u7D30\u80DE\u9AA8\u683C\u3001\u306E5\u5927\u5206\u5B50\u7FA4\u3067\u69CB\u7BC9\u3055\u308C\u3066\u3044\u308B\u3002\u8003\u3048\u3088\u3046\u306B\u3088\u3063\u3066\u306F\u3001\u3053\u308C\u3089\u5168\u90E8\u304C\u300C\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u300D\u3060\u304C\u3001\u901A\u5E38\u306F\u3001\u300C1\u30682\u300D\u3092\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u3068\u3057\u3001\u300C3\u30014\u30015\u300D\u306F\u7D30\u80DE\u63A5\u7740\u5206\u5B50\u306E\u7BC4\u7587\u306B\u5165\u308C\u306A\u3044\u3002\u3053\u3053\u3067\u3082\u305D\u306E\u5B9A\u7FA9\u306B\u5F93\u3063\u305F\u3002 \u7D30\u80DE\u63A5\u7740\u5206\u5B50\u306F\u3001\u30D5\u30A1\u30DF\u30EA\u30FC\u3084\u30A2\u30A4\u30BD\u30D5\u30A9\u30FC\u30E0\u3092\u542B\u3081\u308B\u3068\u6570\u767E\u7A2E\u985E\u306B\u304A\u3088\u3076\u305F\u3081\u3001\u3053\u3053\u3067\u306F\u3001\u30D5\u30A1\u30DF\u30EA\u30FC\u3084\u30A2\u30A4\u30BD\u30D5\u30A9\u30FC\u30E0\u306F\u4EE3\u8868\u5206\u5B50\u3092\u793A\u3057\u305F\u3002"@ja , "Atxikipen molekulak zelula mintzean aurkitzen diren etaatxikipen zelularrean zelula-zelula edo zelula-matrize estrazelularraren arteko loturan parten hartzen duten molekulak dira. Ingelesez CAM (Cell Adhesion Molecules) bezala ezagutzen dira. Molekula hauek zelula mintzean daude eta hiru atal izaten dituzte: zitoeskeletoarekin elkarrekintzak izango dituen atal intrazelular bat, zelula mintzaren barruan dagoen atala eta beste atxikipen molekula batzuekin elkarrekintzak izango dituen atal estrazelular bat. Mota bereko atxikipen molekulekin ematen badira elkarrekintzak, lotura homofiloa dela esaten da eta bestela, lotura heterofiloa izango da."@eu ; dbo:wikiPageWikiLink dbr:Immunological_synapse , dbc:Cell_adhesion_molecules , dbr:Cellular_differentiation , dbr:PSGL-1 , dbr:Synaptic_stabilization , dbr:Cation , dbr:Dissociation_constant , dbr:P-selectin , dbr:Adherens_junction , , dbr:Fucosylation , dbr:Ectoderm , dbr:Apoptosis , dbr:Catenin , dbr:Leukocyte , dbr:Gastrulation , dbr:Heterodimer , dbr:Cadherin , dbr:CDH2 , dbr:Thrombin , dbr:Cell_fate_determination , dbr:Extracellular_environment , dbr:Immunoglobulin , dbr:Mesoderm , dbr:L-selectin , dbr:E-selectin , dbr:Platelets , dbr:Molecular_binding , dbr:Collagen , dbr:Fibronectin_type_III_domain , dbr:Endothelium , dbr:Cell_migration , dbc:Single-pass_transmembrane_proteins , dbr:Fibrinogen , , dbr:CDH4 , dbr:IgCAM , dbr:Glycoproteins , dbr:Cell_membrane , dbr:Cell_adhesion , dbr:Vitronectin , dbr:Ligand , dbr:Platelet , dbr:Trogocytosis , dbr:Cytoskeleton , dbr:Integrin , dbr:Endoderm , dbr:Extracellular , dbr:Proteoglycans , dbr:Extracellular_matrix , dbr:Pattern_recognition_receptor , , dbr:Mucin , dbr:Immunoglobulin_superfamily , dbr:Fibronectin , dbr:Actin , dbr:Addressin , dbr:Selectin , dbr:Transmembrane_receptor . @prefix dbp: . @prefix dbt: . dbr:Cell_adhesion_molecule dbp:wikiPageUsesTemplate dbt:Cell_adhesion_molecules , dbt:Citation_needed , dbt:Reflist , dbt:Portal , dbt:About , dbt:Chem , dbt:Commons_category , dbt:Short_description , dbt:Main ; dbo:wikiPageRevisionID 1104924399 . @prefix xsd: . dbr:Cell_adhesion_molecule dbo:wikiPageLength "16415"^^xsd:nonNegativeInteger ; dbo:wikiPageID 1628547 . @prefix owl: . dbr:Cell_adhesion_molecule owl:sameAs , , , , . @prefix dbpedia-et: . dbr:Cell_adhesion_molecule owl:sameAs dbpedia-et:Adhesioonimolekulid , , , dbr:Cell_adhesion_molecule , . @prefix wikidata: . dbr:Cell_adhesion_molecule owl:sameAs wikidata:Q187637 , , . @prefix ns15: . dbr:Cell_adhesion_molecule owl:sameAs ns15:oyjw , . @prefix yago-res: . dbr:Cell_adhesion_molecule owl:sameAs yago-res:Cell_adhesion_molecule . @prefix dbpedia-eu: . dbr:Cell_adhesion_molecule owl:sameAs dbpedia-eu:Atxikipen_molekula , . @prefix dbpedia-it: . dbr:Cell_adhesion_molecule owl:sameAs dbpedia-it:Molecole_di_adesione , , . @prefix dbpedia-nl: . dbr:Cell_adhesion_molecule owl:sameAs dbpedia-nl:Celadhesiemoleculen . @prefix gold: . dbr:Cell_adhesion_molecule gold:hypernym dbr:Proteins . @prefix prov: . dbr:Cell_adhesion_molecule prov:wasDerivedFrom ; 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