@prefix dbo: .
@prefix dbr: .
dbo:wikiPageWikiLink dbr:Ixabepilone .
@prefix foaf: .
@prefix wikipedia-en: .
wikipedia-en:Ixabepilone foaf:primaryTopic dbr:Ixabepilone .
dbr:Endometrial_cancer dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Bristol_Myers_Squibb dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Chemotherapy-induced_peripheral_neuropathy dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Post-chemotherapy_cognitive_impairment dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:ATC_code_L01 dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Linezolid dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:List_of_antineoplastic_agents dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:ATC_code_L01DC04 dbo:wikiPageWikiLink dbr:Ixabepilone ;
dbo:wikiPageRedirects dbr:Ixabepilone .
dbr:Porphyria dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Kolliphor_EL dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Myxobacteria dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Diverted_total_synthesis dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Epothilone dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Causes_of_cancer_pain dbo:wikiPageWikiLink dbr:Ixabepilone .
@prefix rdf: .
@prefix yago: .
dbr:Ixabepilone rdf:type yago:Diol114835980 ,
yago:Part113809207 ,
dbo:Drug .
@prefix ns6: .
dbr:Ixabepilone rdf:type ns6:ChemicalObject ,
dbo:ChemicalSubstance ,
yago:Abstraction100002137 ,
yago:Liquid114940386 ,
yago:Relation100031921 .
@prefix owl: .
dbr:Ixabepilone rdf:type owl:Thing ,
yago:Matter100020827 ,
yago:OrganicCompound114727670 ,
yago:Material114580897 ,
yago:Fluid114939900 ,
yago:Compound114818238 ,
yago:Chemical114806838 ,
yago:Substance100019613 ,
yago:WikicatAmides .
@prefix umbel-rc: .
dbr:Ixabepilone rdf:type umbel-rc:DrugProduct ,
yago:Amide114724264 ,
yago:Ketone114926294 ,
yago:PhysicalEntity100001930 ,
yago:WikicatKetones ,
yago:WikicatDiols .
@prefix wikidata: .
dbr:Ixabepilone rdf:type wikidata:Q8386 ,
yago:Alcohol114708720 .
@prefix rdfs: .
dbr:Ixabepilone rdfs:label "Ixabepilone"@en ,
"Iksabepilon"@pl ,
"\u0625\u0643\u0633\u0627\u0628\u064A\u0628\u064A\u0644\u0648\u0646"@ar ;
rdfs:comment "\u064A\u064F\u0639\u062F \u0639\u0642\u0627\u0631 \u0625\u0643\u0633\u0627\u0628\u064A\u0628\u064A\u0644\u0648\u0646 (\u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u0623\u064A\u0636\u064B\u0627 \u0628\u0627\u0633\u0645 azaepothilone B\u060C \u0648\u0627\u0644\u0630\u064A \u064A\u062D\u0645\u0644 \u0627\u0644\u0627\u0633\u0645 \u0627\u0644\u0631\u0645\u0632\u064A BMS-247550 )\u062F\u0648\u0627\u0621\u064B\u0627 \u0635\u064A\u062F\u0644\u0627\u0646\u064A\u064B\u0627 \u0637\u0648\u0631\u062A\u0647 \u0634\u0631\u0643\u0629 \u0628\u0631\u064A\u0633\u062A\u0648\u0644-\u0645\u0627\u064A\u0631\u0632 \u0633\u0643\u0648\u064A\u0628 \u0643\u062F\u0648\u0627\u0621 \u0639\u0644\u0627\u062C\u064A \u0643\u064A\u0645\u064A\u0627\u0626\u064A \u0644\u0644\u0633\u0631\u0637\u0627\u0646."@ar ,
"Iksabepilon \u2013 organiczny zwi\u0105zek chemiczny, p\u00F3\u0142syntetyczny analog epotilonu B, nale\u017C\u0105cy do grupy epotilon\u00F3w. Jest on substratem enzymu CYP3A4."@pl ,
"Ixabepilone (INN; also known as azaepothilone B, codenamed BMS-247550) is a pharmaceutical drug developed by Bristol-Myers Squibb as a chemotherapeutic medication for cancer."@en ;
foaf:depiction .
@prefix dcterms: .
@prefix dbc: .
dbr:Ixabepilone dcterms:subject dbc:Thiazoles ,
dbc:Epoxides ,
dbc:Bristol_Myers_Squibb ,
dbc:Lactams ,
dbc:Mitotic_inhibitors ;
dbo:abstract "Ixabepilone (INN; also known as azaepothilone B, codenamed BMS-247550) is a pharmaceutical drug developed by Bristol-Myers Squibb as a chemotherapeutic medication for cancer."@en ,
"Iksabepilon \u2013 organiczny zwi\u0105zek chemiczny, p\u00F3\u0142syntetyczny analog epotilonu B, nale\u017C\u0105cy do grupy epotilon\u00F3w. Jest on substratem enzymu CYP3A4."@pl ,
"\u064A\u064F\u0639\u062F \u0639\u0642\u0627\u0631 \u0625\u0643\u0633\u0627\u0628\u064A\u0628\u064A\u0644\u0648\u0646 (\u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u0623\u064A\u0636\u064B\u0627 \u0628\u0627\u0633\u0645 azaepothilone B\u060C \u0648\u0627\u0644\u0630\u064A \u064A\u062D\u0645\u0644 \u0627\u0644\u0627\u0633\u0645 \u0627\u0644\u0631\u0645\u0632\u064A BMS-247550 )\u062F\u0648\u0627\u0621\u064B\u0627 \u0635\u064A\u062F\u0644\u0627\u0646\u064A\u064B\u0627 \u0637\u0648\u0631\u062A\u0647 \u0634\u0631\u0643\u0629 \u0628\u0631\u064A\u0633\u062A\u0648\u0644-\u0645\u0627\u064A\u0631\u0632 \u0633\u0643\u0648\u064A\u0628 \u0643\u062F\u0648\u0627\u0621 \u0639\u0644\u0627\u062C\u064A \u0643\u064A\u0645\u064A\u0627\u0626\u064A \u0644\u0644\u0633\u0631\u0637\u0627\u0646."@ar ;
dbo:wikiPageWikiLink dbr:Food_and_Drug_Administration ,
dbc:Thiazoles ,
dbr:Capecitabine ,
dbr:Liver ,
dbc:Bristol_Myers_Squibb ,
dbr:Taxane ,
dbr:Intravenous_therapy ,
dbr:Metabolic_stability ,
dbr:CYP3A4 ,
dbr:Chemotherapy ,
dbr:Structural_analog ,
dbr:Breast_cancer ,
,
dbr:Bristol-Myers_Squibb ,
dbc:Lactams ,
dbr:Anthracycline ,
dbc:Mitotic_inhibitors ,
dbr:Pharmacokinetics ,
dbr:Taxol ,
dbr:Metastasis ,
dbc:Epoxides ,
dbr:Kidney ,
dbr:Epothilone ,
dbr:International_Nonproprietary_Name ,
dbr:European_Medicines_Agency ,
dbr:Microtubule ,
dbr:Semi-synthetic ,
dbr:Sorangium_cellulosum ,
dbr:Medicinal_chemistry .
@prefix dbp: .
@prefix dbt: .
dbr:Ixabepilone dbp:wikiPageUsesTemplate dbt:Cascite ,
dbt:Chemspidercite ,
dbt:Stdinchicite ,
dbt:Fdacite ,
dbt:Drugbox ,
dbt:Chemotherapeutic_agents ,
dbt:Reflist ,
dbt:Drugbankcite ,
,
dbt:Keggcite ,
dbt:Ebicite ;
dbo:thumbnail ;
dbo:wikiPageRevisionID 1092789517 ;
dbo:wikiPageExternalLink ,
.
@prefix xsd: .
dbr:Ixabepilone dbo:wikiPageLength "8005"^^xsd:nonNegativeInteger ;
dbo:wikiPageID 11979825 ;
owl:sameAs dbr:Ixabepilone .
@prefix dbpedia-sr: .
dbr:Ixabepilone owl:sameAs dbpedia-sr:Iksabepilon .
@prefix dbpedia-pl: .
dbr:Ixabepilone owl:sameAs dbpedia-pl:Iksabepilon ,
,
,
wikidata:Q11711607 .
@prefix ns18: .
dbr:Ixabepilone owl:sameAs ns18:E9C2 ,
,
.
@prefix dbpedia-vi: .
dbr:Ixabepilone owl:sameAs dbpedia-vi:Ixabepilone .
@prefix yago-res: .
dbr:Ixabepilone owl:sameAs yago-res:Ixabepilone .
@prefix dbpedia-sh: .
dbr:Ixabepilone owl:sameAs dbpedia-sh:Iksabepilon .
@prefix gold: .
dbr:Ixabepilone gold:hypernym dbr:Analog .
@prefix prov: .
dbr:Ixabepilone prov:wasDerivedFrom ;
foaf:isPrimaryTopicOf wikipedia-en:Ixabepilone ;
dbp:chembl 1201752 ;
dbo:chEMBL "1201752" ;
dbp:atcSuffix "DC04"@en ;
dbp:verifiedfields "changed"@en ;
dbo:alternativeName "Ixempra"@en ;
dbp:s 1 ;
dbp:n 2 ;
dbp:chemspiderid 20145579 ;
dbp:c 27 ;
dbp:verifiedrevid 477495917 ;
dbp:h 42 ;
dbo:pubchem "6445540" ;
dbp:routesOfAdministration dbr:Intravenous_therapy ;
dbp:o 5 ;
dbp:pubchem 6445540 ;
dbp:stdinchikey "FABUFPQFXZVHFB-PVYNADRNSA-N"@en ;
dbp:smiles "Cc3nccs3"@en ;
dbo:fdaUniiCode "K27005NP0A" ;
dbp:iupacName 99 ,
-610 ,
"heptadecane-8,12-dione"@en ;
dbp:unii "K27005NP0A"@en ;
dbp:casNumber 219989 ;
dbp:atcPrefix "L01"@en ;
dbp:stdinchi 1 ;
dbo:casNumber "219989-84-1" ;
dbp:medlineplus "a608042"@en ;
dbo:medlinePlus "a608042" ;
dbp:licenceUs "Ixabepilone"@en ;
dbp:pregnancyUs "D"@en ;
dbp:iupharLigand 6824 ;
dbp:proteinBound 67 ;
dbp:width 250 ;
dbp:legalUs "Rx-only"@en ;
dbp:synonyms "Azaepothilone B"@en ;
dbo:kegg "D04645" ;
dbp:excretion "Fecal and renal"@en .
@prefix dbd: .
dbr:Ixabepilone dbp:eliminationHalfLife "187200.0"^^dbd:second ;
dbo:drugbank "DB04845" ;
dbp:drugbank "DB04845"@en ;
dbp:tradename "Ixempra"@en ;
dbp:bioavailability "N/A"@en ;
dbp:metabolism "Extensive, hepatic, CYP3A4-mediated"@en ;
dbp:kegg "D04645"@en .
dbr:Sorangium_cellulosum dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Index_of_oncology_articles dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:Microtubule dbo:wikiPageWikiLink dbr:Ixabepilone .
dbr:C27H42N2O5S dbo:wikiPageWikiLink dbr:Ixabepilone ;
dbo:wikiPageRedirects dbr:Ixabepilone .
dbr:Ixempra dbo:wikiPageWikiLink dbr:Ixabepilone ;
dbo:wikiPageRedirects dbr:Ixabepilone .
dbr:ATCvet_code_QL01DC04 dbo:wikiPageWikiLink dbr:Ixabepilone ;
dbo:wikiPageRedirects dbr:Ixabepilone .
dbr:BMS-247550 dbo:wikiPageWikiLink dbr:Ixabepilone ;
dbo:wikiPageRedirects dbr:Ixabepilone .