Methyllycaconitine
Méthyllycaconitine
La méthyllycaconitine (MLA) est un très toxique que l'on trouve dans les plantes du genre Delphinium. C'est un composé de type N-(méthylsuccinyl)-anthranoyllycoctonine.
Methyllycaconitine (MLA) is a diterpenoid alkaloid found in many species of Delphinium (larkspurs). In common with many other diterpenoid alkaloids, it is toxic to animals, although the acute toxicity varies with species. Early research was focused on identifying, and characterizing the properties of methyllycaconitine as one of the principal toxins in larkspurs responsible for livestock poisoning in the mountain rangelands of North America. Methyllycaconitine has been explored as a possible therapeutic agent for the treatment of spastic paralyses in man, and it has been shown to have insecticidal properties. Most recently, it has become an important molecular probe for studying the pharmacology of the nicotinic acetylcholine receptor.
7180756
1107774857
37
21019
510275
4470788
50
2
10
5311278
CCN1CC2COCC7=CC=CC=C7N8CCCC
8
Methyllycaconitine (MLA) is a diterpenoid alkaloid found in many species of Delphinium (larkspurs). In common with many other diterpenoid alkaloids, it is toxic to animals, although the acute toxicity varies with species. Early research was focused on identifying, and characterizing the properties of methyllycaconitine as one of the principal toxins in larkspurs responsible for livestock poisoning in the mountain rangelands of North America. Methyllycaconitine has been explored as a possible therapeutic agent for the treatment of spastic paralyses in man, and it has been shown to have insecticidal properties. Most recently, it has become an important molecular probe for studying the pharmacology of the nicotinic acetylcholine receptor.
La méthyllycaconitine (MLA) est un très toxique que l'on trouve dans les plantes du genre Delphinium. C'est un composé de type N-(méthylsuccinyl)-anthranoyllycoctonine.
28880
21019-30-7
510275
8H7EX9Z9QE
5311278