{ "d" : { "results": [ { "__metadata": { "uri": "http://dbpedia.org/resource/Protein_N-terminal_methyltransferase" }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/ontology/Biomolecule" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Abstraction100002137" } }, "http://dbpedia.org/ontology/wikiPageLength": "2774", "http://dbpedia.org/ontology/wikiPageWikiLink": { "__deferred": { "uri": "http://dbpedia.org/resource/Category:EC_2.1.1" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Macromolecule114944888" } }, "http://www.w3.org/2000/01/rdf-schema#comment": "Protein N-terminal methyltransferase (EC 2.1.1.244, NMT1 (gene), METTL11A (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:N-terminal-(A,P,S)PK-(protein) methyltransferase. This enzyme catalyses the following chemical reaction This enzyme methylates the N-terminus of _target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys.", "http://xmlns.com/foaf/0.1/name": "Protein N-terminal methyltransferase", "http://dbpedia.org/property/iubmbEcNumber": "2", "http://dbpedia.org/ontology/wikiPageWikiLink": { "__deferred": { "uri": "http://dbpedia.org/resource/N-terminus" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Matter100020827" } }, "http://dbpedia.org/ontology/wikiPageWikiLink": { "__deferred": { "uri": "http://dbpedia.org/resource/List_of_enzymes" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/ontology/Enzyme" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Unit109465459" } }, "http://www.w3.org/2002/07/owl#sameAs": { "__deferred": { "uri": "http://www.wikidata.org/entity/Q5150282" } }, "http://dbpedia.org/ontology/ecNumber": "2.1.1.244", "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/OrganicCompound114727670" } }, "http://dbpedia.org/property/wikiPageUsesTemplate": { "__deferred": { "uri": "http://dbpedia.org/resource/Template:Portal_bar" } }, "http://dbpedia.org/property/wikiPageUsesTemplate": { "__deferred": { "uri": "http://dbpedia.org/resource/Template:Enzymes" } }, "http://xmlns.com/foaf/0.1/isPrimaryTopicOf": { "__deferred": { "uri": "http://en.wikipedia.org/wiki/Protein_N-terminal_methyltransferase" } }, "http://dbpedia.org/ontology/wikiPageID": "38609162", "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://www.w3.org/2002/07/owl#Thing" } }, "http://dbpedia.org/property/wikiPageUsesTemplate": { "__deferred": { "uri": "http://dbpedia.org/resource/Template:EC_number" } }, "http://dbpedia.org/property/name": "Protein N-terminal methyltransferase", "http://dbpedia.org/property/wikiPageUsesTemplate": { "__deferred": { "uri": "http://dbpedia.org/resource/Template:One_carbon_transferases" } }, "http://www.w3.org/2002/07/owl#sameAs": { "__deferred": { "uri": "https://global.dbpedia.org/id/4hqx8" } }, "http://purl.org/dc/terms/subject": { "__deferred": { "uri": "http://dbpedia.org/resource/Category:EC_2.1.1" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Catalyst114723628" } }, "http://dbpedia.org/property/wikiPageUsesTemplate": { "__deferred": { "uri": "http://dbpedia.org/resource/Template:Reflist" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Material114580897" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Molecule114682133" } }, "http://dbpedia.org/ontology/abstract": "Protein N-terminal methyltransferase (EC 2.1.1.244, NMT1 (gene), METTL11A (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:N-terminal-(A,P,S)PK-(protein) methyltransferase. This enzyme catalyses the following chemical reaction (1) 3 S-adenosyl-L-methionine + N-terminal-(A,S)PK-[protein] 3 S-adenosyl-L-homocysteine + N-terminal-N,N,N-trimethyl-N-(A,S)PK-[protein] (overall reaction)(1a) S-adenosyl-L-methionine + N-terminal-(A,S)PK-[protein] S-adenosyl-L-homocysteine + N-terminal-N-methyl-N-(A,S)PK-[protein](1b) S-adenosyl-L-methionine + N-terminal-N-methyl-N-(A,S)PK-[protein] S-adenosyl-L-homocysteine + N-terminal-N,N-dimethyl-N-(A,S)PK-[protein](1c) S-adenosyl-L-methionine + N-terminal-N,N-dimethyl-N-(A,S)PK-serine-[protein] S-adenosyl-L-homocysteine + N-terminal-N,N,N-trimethyl-N-(A,S)PK-[protein](2) 2 S-adenosyl-L-methionine + N-terminal-PPK-[protein] 2 S-adenosyl-L-homocysteine + N-terminal-N,N-dimethyl-N-PPK-[protein] (overall reaction)(2a) S-adenosyl-L-methionine + N-terminal-PPK-[protein] S-adenosyl-L-homocysteine + N-terminal-N-methyl-N-PPK-[protein](2b) S-adenosyl-L-methionine + N-terminal-N-methyl-N-PPK-[protein] S-adenosyl-L-homocysteine + N-terminal-N,N-dimethyl-N-PPK-[protein] This enzyme methylates the N-terminus of _target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys.", "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Enzyme114732946" } }, "http://dbpedia.org/property/wikiPageUsesTemplate": { "__deferred": { "uri": "http://dbpedia.org/resource/Template:Infobox_enzyme" } }, "http://www.w3.org/2002/07/owl#sameAs": { "__deferred": { "uri": "http://rdf.freebase.com/ns/m.0r8lv1s" } }, "http://dbpedia.org/ontology/wikiPageWikiLink": { "__deferred": { "uri": "http://dbpedia.org/resource/Enzyme" } }, "http://www.w3.org/2002/07/owl#sameAs": { "__deferred": { "uri": "http://sh.dbpedia.org/resource/Protein_N-terminal_metiltransferaza" } }, "http://www.w3.org/2000/01/rdf-schema#label": "Protein N-terminal methyltransferase", "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Protein114728724" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/PhysicalEntity100001930" } }, "http://dbpedia.org/property/ecNumber": "2.1", "http://dbpedia.org/ontology/wikiPageWikiLink": { "__deferred": { "uri": "http://dbpedia.org/resource/S-adenosyl-L-methionine" } }, "http://www.w3.org/2002/07/owl#sameAs": { "__deferred": { "uri": "http://sr.dbpedia.org/resource/Protein_N-terminal_metiltransferaza" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://www.wikidata.org/entity/Q206229" } }, "http://dbpedia.org/ontology/wikiPageWikiLink": { "__deferred": { "uri": "http://dbpedia.org/resource/S-adenosyl-L-homocysteine" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Activator114723079" } }, "http://dbpedia.org/ontology/wikiPageWikiLink": { "__deferred": { "uri": "http://dbpedia.org/resource/Catalysis" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Substance100019613" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Chemical114806838" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Compound114818238" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Part113809207" } }, "http://dbpedia.org/ontology/wikiPageRevisionID": "918609866", "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Thing100002452" } }, "http://dbpedia.org/ontology/wikiPageWikiLink": { "__deferred": { "uri": "http://dbpedia.org/resource/Chemical_reaction" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://dbpedia.org/class/yago/Relation100031921" } }, "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": { "__deferred": { "uri": "http://www.wikidata.org/entity/Q8047" } }, "http://www.w3.org/ns/prov#wasDerivedFrom": { "__deferred": { "uri": "http://en.wikipedia.org/wiki/Protein_N-terminal_methyltransferase?oldid=918609866&ns=0" } }, "http://dbpedia.org/property/wikiPageUsesTemplate": { "__deferred": { "uri": "http://dbpedia.org/resource/Template:MeshName" } } } ], "__count": "1" } }
  NODES