http://dbpedia.org/data/Sazetidine_A.atom 2024-12-28T09:32:44.118843Z http://dbpedia.org/resource/Sazetidine_A 2024-12-28T09:32:44.118843Z 820231 20 1 WONBUILDJNKYCB-AWEZNQCLSA-N 1110198511 OCCCCC#Cc1ccOCC2CCN2 Sazetidine A 451222236 820231-95-6 15 10155861 2 240 11983356 3388 23998226 2 6 260.331 Sazetidine A (AMOP-H-OH) is a drug which acts as a subtype selective partial agonist at α4β2 neural nicotinic acetylcholine receptors, acting as an agonist at (α4)2(β2)3 pentamers, but as an antagonist at (α4)3(β2)2 pentamers. It has potent analgesic effects in animal studies comparable to those of epibatidine, but with less toxicity, and also has antidepressant action. Sazetidine A (AMOP-H-OH) is a drug which acts as a subtype selective partial agonist at α4β2 neural nicotinic acetylcholine receptors, acting as an agonist at (α4)2(β2)3 pentamers, but as an antagonist at (α4)3(β2)2 pentamers. It has potent analgesic effects in animal studies comparable to those of epibatidine, but with less toxicity, and also has antidepressant action. 11983356

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