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{ "type" : "literal", "value" : "Situs inversus (\u00E9galement appel\u00E9 situs transversus ou oppositus) est un terme de m\u00E9decine d\u00E9signant une anomalie cong\u00E9nitale dans laquelle les principaux visc\u00E8res et organes sont invers\u00E9s dans une position en miroir par rapport \u00E0 leur disposition normale (le plan sagittal). La disposition normale est appel\u00E9e . Elle est d\u00E9finie par la position des oreillettes : \u00E0 droite pour l'oreillette droite et \u00E0 gauche pour l'oreillette gauche. Dans le situs inversus, l'oreillette droite est \u00E0 gauche et l'oreillette gauche \u00E0 droite. Dans d'autres cas plus rares, le situs ne peut pas \u00EAtre d\u00E9termin\u00E9, affection connue sous le nom de situs ambiguus. Ces affections sont regroup\u00E9es sous le terme g\u00E9n\u00E9rique d'h\u00E9t\u00E9rotaxie." , "lang" : "fr" } ,
{ "type" : "literal", "value" : "Il situs inversus \u00E8 una condizione congenita dove gli organi sono invertiti in modo speculare rispetto alla loro usuale posizione, che \u00E8 detta invece , ed \u00E8 caratterizzata da destrocardia, fegato a sinistra e milza a destra. La dineina \u00E8 la proteina determinante per l'induzione della lateralizzazione: essa \u00E8 infatti costituente dei flagelli che creano, nell'embrione, le correnti attraverso le quali gli ormoni inerenti allo sviluppo dell'individuo vengono direzionati secondo un ordine preciso." , "lang" : "it" } ,
{ "type" : "literal", "value" : "\u0397 \u03B1\u03BD\u03B1\u03C3\u03C4\u03C1\u03BF\u03C6\u03AE \u03BF\u03C1\u03B3\u03AC\u03BD\u03C9\u03BD (situs inversus, \u03B1\u03C0\u03BF\u03BA\u03B1\u03BB\u03B5\u03AF\u03C4\u03B1\u03B9 \u03B5\u03C0\u03AF\u03C3\u03B7\u03C2 situs transversus \u03AE oppositus) \u03B5\u03AF\u03BD\u03B1\u03B9 \u03C3\u03C5\u03B3\u03B3\u03B5\u03BD\u03AE\u03C2 \u03BA\u03B1\u03C4\u03AC\u03C3\u03C4\u03B1\u03C3\u03B7, \u03C3\u03C4\u03B7\u03BD \u03BF\u03C0\u03BF\u03AF\u03B1 \u03C4\u03B1 \u03BA\u03CD\u03C1\u03B9\u03B1 \u03C3\u03C0\u03BB\u03B1\u03C7\u03BD\u03B9\u03BA\u03AC \u03CC\u03C1\u03B3\u03B1\u03BD\u03B1 \u03B1\u03BD\u03C4\u03B9\u03C3\u03C4\u03C1\u03AD\u03C6\u03BF\u03BD\u03C4\u03B1\u03B9 \u03AE \u03B1\u03BD\u03C4\u03B9\u03BA\u03B1\u03C4\u03BF\u03C0\u03C4\u03C1\u03AF\u03B6\u03BF\u03BD\u03C4\u03B1\u03B9 \u03B1\u03C0\u03CC \u03C4\u03B9\u03C2 \u03BA\u03B1\u03BD\u03BF\u03BD\u03B9\u03BA\u03AD\u03C2 \u03C4\u03BF\u03C5\u03C2 \u03B8\u03AD\u03C3\u03B5\u03B9\u03C2. \u0397 \u03BA\u03B1\u03BD\u03BF\u03BD\u03B9\u03BA\u03AE \u03B4\u03B9\u03AC\u03C4\u03B1\u03BE\u03B7 \u03C4\u03C9\u03BD \u03B5\u03C3\u03C9\u03C4\u03B5\u03C1\u03B9\u03BA\u03CE\u03BD \u03BF\u03C1\u03B3\u03AC\u03BD\u03C9\u03BD \u03B5\u03AF\u03BD\u03B1\u03B9 \u03B3\u03BD\u03C9\u03C3\u03C4\u03AE \u03C9\u03C2 \u03C4\u03BF\u03C0\u03BF\u03B8\u03B5\u03C3\u03AF\u03B1 solitus . \u0391\u03BD \u03BA\u03B1\u03B9 \u03C4\u03B1 \u03BA\u03B1\u03C1\u03B4\u03B9\u03B1\u03BA\u03AC \u03C0\u03C1\u03BF\u03B2\u03BB\u03AE\u03BC\u03B1\u03C4\u03B1 \u03B5\u03AF\u03BD\u03B1\u03B9 \u03C0\u03B9\u03BF \u03C3\u03C5\u03BD\u03B7\u03B8\u03B9\u03C3\u03BC\u03AD\u03BD\u03B1, \u03C0\u03BF\u03BB\u03BB\u03AC \u03AC\u03C4\u03BF\u03BC\u03B1 \u03BC\u03B5 \u03B1\u03BD\u03B1\u03C3\u03C4\u03C1\u03BF\u03C6\u03AE \u03BF\u03C1\u03B3\u03AC\u03BD\u03C9\u03BD \u03B4\u03B5\u03BD \u03AD\u03C7\u03BF\u03C5\u03BD \u03B9\u03B1\u03C4\u03C1\u03B9\u03BA\u03AC \u03C3\u03C5\u03BC\u03C0\u03C4\u03CE\u03BC\u03B1\u03C4\u03B1 \u03AE \u03B5\u03C0\u03B9\u03C0\u03BB\u03BF\u03BA\u03AD\u03C2 \u03C0\u03BF\u03C5 \u03C0\u03C1\u03BF\u03BA\u03CD\u03C0\u03C4\u03BF\u03C5\u03BD \u03B1\u03C0\u03CC \u03C4\u03B7\u03BD \u03C0\u03AC\u03B8\u03B7\u03C3\u03B7, \u03BA\u03B1\u03B9 \u03BC\u03AD\u03C7\u03C1\u03B9 \u03C4\u03B7\u03BD \u03AD\u03BB\u03B5\u03C5\u03C3\u03B7 \u03C4\u03B7\u03C2 \u03C3\u03CD\u03B3\u03C7\u03C1\u03BF\u03BD\u03B7\u03C2 \u03B9\u03B1\u03C4\u03C1\u03B9\u03BA\u03AE\u03C2, \u03C0\u03B1\u03C1\u03AD\u03BC\u03B5\u03BD\u03B5 \u03C3\u03C5\u03BD\u03AE\u03B8\u03C9\u03C2 \u03C7\u03C9\u03C1\u03AF\u03C2 \u03B4\u03B9\u03AC\u03B3\u03BD\u03C9\u03C3\u03B7." , "lang" : "el" } ,
{ "type" : "literal", "value" : "Situs inversus, kortform av det latinska situs inversus viscerum, \u00E4ven situs transverses \u00E4r ett \u00E4rftligt tillst\u00E5nd med omv\u00E4nd eller spegelv\u00E4nd plats f\u00F6r organen i br\u00F6st och bukh\u00E5la. Hj\u00E4rtat och magen \u00E4r placerade till h\u00F6ger och mj\u00E4lten kan vara p\u00E5 h\u00F6ger sida av buken, medan lever, gallbl\u00E5sa och appendix ligger till v\u00E4nster. Lungor, lymfk\u00E4rl, nerver och tarmar \u00E4r omv\u00E4nda j\u00E4mf\u00F6rt med det normala. Personer som f\u00F6ds med situs inversus lever sannolikt ett normalt liv, om organen i \u00F6vrigt \u00E4r utan anm\u00E4rkning. Ibland uppt\u00E4cks avvikelsen f\u00F6rst vid l\u00E4karunders\u00F6kning av andra sk\u00E4l." , "lang" : "sv" } ,
{ "type" : "literal", "value" : "Situs inversus (ICD-10 Q89.3) is een zeldzame verstoring van de links-rechtsconfiguratie binnen het lichaam. Met andere woorden, de organen zijn in spiegelbeeld gepositioneerd in het lichaam. De lever zit dan bijvoorbeeld links in plaats van rechts. De normale positionering van de organen heet situs solitus. Er kan sprake zijn van een totale situs inversus (situs inversus totalis) of een parti\u00EBle. Het komt voor bij minder dan 1 op de 10.000 mensen. Voor de desbetreffende personen is het belangrijk dat hun artsen dit weten en dat zij dit ook doorgeven aan hun omgeving, dit voor noodgevallen." , "lang" : "nl" } ,
{ "type" : "literal", "value" : "\uB0B4\uC7A5 \uC5ED\uC704\uC99D(\u5167\u81DF\u9006\u4F4D\u75C7, situs inversus, situs transversus, oppositus)\uC740 \uC8FC\uC694 \uAE30\uAD00\uB4E4\uC774 \uC815\uC0C1 \uC704\uCE58\uAC00 \uC544\uB2CC \uBC18\uB300\uB85C, \uC989 \uAC70\uC6B8 \uC704\uCE58\uC5D0 \uC788\uB294 \uC120\uCC9C\uC131 \uC9C8\uBCD1\uC774\uB2E4." , "lang" : "ko" } ,
{ "type" : "literal", "value" : "\u0623\u062D\u0634\u0627\u0621 \u0645\u0639\u0643\u0648\u0633\u0629 \u0627\u0644\u0645\u0648\u0636\u0639 \u0623\u0648 \u0627\u0644\u0627\u0646\u0639\u0643\u0627\u0633 \u0627\u0644\u062C\u0630\u0639\u064A \u0623\u0648 \u0627\u0646\u0642\u0644\u0627\u0628 \u0648\u0636\u0639 \u0627\u0644\u0623\u062D\u0634\u0627\u0621 (\u0628\u0627\u0644\u0625\u0646\u062C\u0644\u064A\u0632\u064A\u0629: Situs inversus) \u0647\u0648 \u062D\u0627\u0644\u0629 \u062E\u0650\u0644\u0642\u064A\u0629 \u064A\u062A\u0645 \u0641\u064A\u0647\u0627 \u0639\u0643\u0633 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062D\u0634\u0648\u064A\u0629 \u0627\u0644\u0631\u0626\u064A\u0633\u064A\u0629 \u0645\u0646 \u0645\u0648\u0627\u0642\u0639\u0647\u0627 \u0627\u0644\u0637\u0628\u064A\u0639\u064A\u0629. \u0648\u0639\u0644\u0649 \u0627\u0644\u0631\u063A\u0645 \u0645\u0646 \u0634\u064A\u0648\u0639 \u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u0642\u0644\u0628\u064A\u0629 \u0641\u064A \u0647\u0630\u0647 \u0627\u0644\u062D\u0627\u0644\u0629\u060C \u0644\u0643\u0646 \u0645\u0639\u0638\u0645 \u0627\u0644\u0630\u064A\u0646 \u064A\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u0623\u062D\u0634\u0627\u0621 \u0645\u0642\u0644\u0648\u0628\u0629 \u0627\u0644\u0645\u0648\u0636\u0639 \u0644\u064A\u0633 \u0644\u062F\u064A\u0647\u0645 \u0623\u064A \u0623\u0639\u0631\u0627\u0636 \u0637\u0628\u064A\u0629 \u0623\u0648 \u0645\u0636\u0627\u0639\u0641\u0627\u062A \u0646\u0627\u062C\u0645\u0629 \u0639\u0646 \u0647\u0630\u0647 \u0627\u0644\u062D\u0627\u0644\u0629\u060C \u062D\u062A\u0649 \u0623\u0646\u0647\u0627 \u0644\u0645 \u062A\u064F\u0634\u062E\u064E\u0651\u0635 \u062D\u062A\u0649 \u0638\u0647\u0648\u0631 \u0627\u0644\u0637\u0628 \u0627\u0644\u062D\u062F\u064A\u062B. \u0647\u0646\u0627\u0643 \u062D\u0627\u0644\u0627\u062A \u0623\u0643\u062B\u0631 \u0646\u062F\u0631\u0629 \u0645\u062B\u0644 \u063A\u0645\u0648\u0636 \u0623\u0648 \u0627\u0644\u062A\u0628\u0627\u0633 \u0627\u0644\u0645\u0648\u0636\u0639 \u0623\u0648 \u0627\u0644\u0645\u0648\u0636\u0639 \u063A\u064A\u0631 \u0627\u0644\u0645\u062A\u062C\u0627\u0646\u0633. \u0648\u0641\u064A \u0647\u0624\u0644\u0627\u0621 \u0627\u0644\u0645\u0631\u0636\u0649\u060C \u0642\u062F \u064A\u062A\u0648\u0627\u062C\u062F \u0627\u0644\u0643\u0628\u062F \u0641\u064A \u062E\u0637 \u0627\u0644\u0648\u0633\u0637\u060C \u0648\u064A\u062A\u0639\u062F\u062F \u0627\u0644\u0637\u062D\u0627\u0644 \u0623\u0648 \u0644\u0627 \u064A\u0648\u062C\u062F \u062A\u0645\u0627\u0645\u064B\u0627 \u0645\u0639 \u0633\u0648\u0621 \u0627\u0633\u062A\u062F\u0627\u0631\u0629 \u0627\u0644\u0623\u0645\u0639\u0627\u0621. \u0648\u0647\u0630\u0627 \u0623\u0643\u062B\u0631 \u0639\u0631\u0636\u0629 \u0644\u0644\u062A\u0633\u0628\u0628 \u0641\u064A \u0645\u0634\u0627\u0643\u0644 \u0637\u0628\u064A\u0629 \u0645\u0646 \u0627\u0644\u0627\u0646\u0639\u0643\u0627\u0633 \u0627\u0644\u062C\u0630\u0639\u064A \u0627\u0644\u0643\u0644\u064A." , "lang" : "ar" } ,
{ "type" : "literal", "value" : "Situs Inversus (tamb\u00E9m conhecido por situs transversus ou situs oppositus) \u00E9 uma condi\u00E7\u00E3o em que alguns \u00F3rg\u00E3os ficam localizados no lado oposto em rela\u00E7\u00E3o ao local onde eles seriam normalmente encontrados. Basicamente consiste numa invers\u00E3o de posi\u00E7\u00E3o dos \u00F3rg\u00E3os dentro do corpo, ficando localizados do lado oposto (como uma imagem de espelho). Cerca de 0,01% das pessoas s\u00E3o atingidas por essa anomalia, que \u00E9 uma heran\u00E7a transmitida por genes autoss\u00F4micos recessivos, sem predile\u00E7\u00E3o por sexo." , "lang" : "pt" } ,
{ "type" : "literal", "value" : "Situs inversus (also called situs transversus or oppositus) is a congenital condition in which the major visceral organs are reversed or mirrored from their normal positions. The normal arrangement of internal organs is known as situs solitus. Although cardiac problems are more common, many people with situs inversus have no medical symptoms or complications resulting from the condition, and until the advent of modern medicine, it was usually undiagnosed." , "lang" : "en" } ,
{ "type" : "literal", "value" : "Situs inversus (lat. invertierte Lage) ist der medizinische Ausdruck f\u00FCr das Vollbild einer Heterotaxie, eine seltene, an sich nicht krankhafte Besonderheit der Anatomie, bei der sich die einzelnen Organe spiegelverkehrt jeweils auf der anderen Seite des K\u00F6rpers befinden. Das Antonym ist der Situs solitus, also die normgerechte Position der Organe im K\u00F6rper. Synonyme des Situs inversus sind: Inversio viscerum, Situs inversus viscerum, Situs inversus totalis, Situs perversus, Situs transversus, Situs rarior, Situs transversus viscerum, Situs oppositus, Situs inversus completus." , "lang" : "de" } ,
{ "type" : "literal", "value" : "El Situs inversus es una extra\u00F1a malformaci\u00F3n gen\u00E9tica que puede afectar a varios \u00F3rganos y tiene un car\u00E1cter gen\u00E9tico. Consiste en una alineaci\u00F3n err\u00F3nea de los \u00F3rganos dentro del cuerpo, coloc\u00E1ndolos del lado opuesto (imagen de espejo). El t\u00E9rmino situs inversus es la forma abreviada de la frase en Lat\u00EDn, situs inversus viscerum, significando posici\u00F3n invertida de los \u00F3rganos internos. La Dextrocardia (el coraz\u00F3n situado en la parte derecha del t\u00F3rax) fue descrita por primera vez por en 1643. Sin embargo, situs inversus fue descrito un siglo m\u00E1s tarde por Matthew Baillie." , "lang" : "es" } ,
{ "type" : "literal", "value" : "\u0422\u0440\u0430\u043D\u0441\u043F\u043E\u0437\u0438\u0446\u0438\u044F \u0432\u043D\u0443\u0442\u0440\u0435\u043D\u043D\u0438\u0445 \u043E\u0440\u0433\u0430\u043D\u043E\u0432 (\u043B\u0430\u0442. situs inversus) (\u0442\u0430\u043A\u0436\u0435 \u043D\u0430\u0437\u044B\u0432\u0430\u0435\u043C\u0430\u044F \u0437\u0435\u0440\u043A\u0430\u043B\u044C\u043D\u044B\u043C [\u043E\u0431\u0440\u0430\u0442\u043D\u044B\u043C] \u0440\u0430\u0441\u043F\u043E\u043B\u043E\u0436\u0435\u043D\u0438\u0435\u043C \u0432\u043D\u0443\u0442\u0440\u0435\u043D\u043D\u0438\u0445 \u043E\u0440\u0433\u0430\u043D\u043E\u0432) \u2014 \u0440\u0435\u0434\u043A\u0438\u0439 \u0432\u0430\u0440\u0438\u0430\u043D\u0442 \u0431\u0438\u043E\u043B\u043E\u0433\u0438\u0447\u0435\u0441\u043A\u043E\u0439 \u0430\u043D\u043E\u043C\u0430\u043B\u0438\u0438, \u0432 \u043A\u043E\u0442\u043E\u0440\u043E\u043C \u043E\u0441\u043D\u043E\u0432\u043D\u044B\u0435 \u0432\u043D\u0443\u0442\u0440\u0435\u043D\u043D\u0438\u0435 \u043E\u0440\u0433\u0430\u043D\u044B \u0438\u043C\u0435\u044E\u0442 \u0437\u0435\u0440\u043A\u0430\u043B\u044C\u043D\u043E\u0435 \u0440\u0430\u0441\u043F\u043E\u043B\u043E\u0436\u0435\u043D\u0438\u0435 \u043F\u043E \u0441\u0440\u0430\u0432\u043D\u0435\u043D\u0438\u044E \u0441 \u043E\u0431\u044B\u0447\u043D\u044B\u043C \u043D\u043E\u0440\u043C\u0430\u043B\u044C\u043D\u044B\u043C \u043F\u043E\u043B\u043E\u0436\u0435\u043D\u0438\u0435\u043C: \u0432\u0435\u0440\u0445\u0443\u0448\u043A\u0430 \u0441\u0435\u0440\u0434\u0446\u0430 \u043E\u0431\u0440\u0430\u0449\u0435\u043D\u0430 \u0432\u043F\u0440\u0430\u0432\u043E (\u0442\u043E \u0435\u0441\u0442\u044C \u0441\u0435\u0440\u0434\u0446\u0435 \u043D\u0430\u0445\u043E\u0434\u0438\u0442\u0441\u044F \u0441 \u043F\u0440\u0430\u0432\u043E\u0439 \u0441\u0442\u043E\u0440\u043E\u043D\u044B), \u043F\u0435\u0447\u0435\u043D\u044C \u0440\u0430\u0441\u043F\u043E\u043B\u043E\u0436\u0435\u043D\u0430 \u0441\u043B\u0435\u0432\u0430, \u0436\u0435\u043B\u0443\u0434\u043E\u043A \u2014 \u0441\u043F\u0440\u0430\u0432\u0430.\u041E\u0431\u044B\u0447\u043D\u043E\u0435 \u043D\u043E\u0440\u043C\u0430\u043B\u044C\u043D\u043E\u0435 \u0440\u0430\u0441\u043F\u043E\u043B\u043E\u0436\u0435\u043D\u0438\u0435 \u043E\u0440\u0433\u0430\u043D\u043E\u0432 \u043D\u0430 \u043B\u0430\u0442\u044B\u043D\u0438 \u043D\u0430\u0437\u044B\u0432\u0430\u0435\u0442\u0441\u044F situs solitus. \u0412 \u0440\u0435\u0434\u043A\u0438\u0445 \u0441\u043B\u0443\u0447\u0430\u044F\u0445 \u0432\u0441\u0442\u0440\u0435\u0447\u0430\u0435\u0442\u0441\u044F \u043D\u0435\u043E\u043F\u0440\u0435\u0434\u0435\u043B\u0451\u043D\u043D\u043E\u0435 \u043F\u043E\u043B\u043E\u0436\u0435\u043D\u0438\u0435 \u0432\u043D\u0443\u0442\u0440\u0435\u043D\u043D\u0438\u0445 \u043E\u0440\u0433\u0430\u043D\u043E\u0432, \u043A\u043E\u0442\u043E\u0440\u043E\u0435 \u043D\u0430\u0437\u044B\u0432\u0430\u0435\u0442\u0441\u044F \u0433\u0435\u0442\u0435\u0440\u043E\u0442\u0430\u043A\u0441\u0438\u044F, \u0438\u043B\u0438 situs ambiguous (\u0431\u0438\u043E\u043B\u043E\u0433\u0438\u0447\u0435\u0441\u043A\u0430\u044F \u043D\u043E\u0440\u043C\u0430\u043B\u044C\u043D\u043E\u0441\u0442\u044C \u0433\u0435\u0442\u0435\u0440\u043E\u0442\u0430\u043A\u0441\u0438\u0438 [\u0432 \u043E\u0442\u043B\u0438\u0447\u0438\u0435 \u043E\u0442 situs solitus \u0438 situs inversus] \u0443\u0436\u0435 \u0441\u043F\u043E\u0440\u043D\u0430)." , "lang" : "ru" } ] ,
"http://www.w3.org/2000/01/rdf-schema#seeAlso" : [ { "type" : "uri", "value" : "http://dbpedia.org/resource/List_of_fictional_characters_with_situs_inversus" } ] ,
"http://xmlns.com/foaf/0.1/name" : [ { "type" : "literal", "value" : "Situs inversus" , "lang" : "en" } ] ,
"http://xmlns.com/foaf/0.1/depiction" : [ { "type" : "uri", "value" : "http://commons.wikimedia.org/wiki/Special:FilePath/Situs_inversus_-_Mirrored_heart_and_lungs.jpg" } ,
{ "type" : "uri", "value" : "http://commons.wikimedia.org/wiki/Special:FilePath/Primary_ciliary_dyskinesia_7.jpg" } ,
{ "type" : "uri", "value" : "http://commons.wikimedia.org/wiki/Special:FilePath/Primary_ciliary_dyskinesia-10.jpg" } ,
{ "type" : "uri", "value" : "http://commons.wikimedia.org/wiki/Special:FilePath/Autorecessive.svg" } ] ,
"http://purl.org/dc/terms/subject" : [ { "type" : "uri", "value" : "http://dbpedia.org/resource/Category:Autosomal_recessive_disorders" } ,
{ "type" : "uri", "value" : "http://dbpedia.org/resource/Category:Congenital_disorders" } ,
{ "type" : "uri", "value" : "http://dbpedia.org/resource/Category:Motor_skills" } ,
{ "type" : "uri", "value" : "http://dbpedia.org/resource/Category:Rare_diseases" } ] ,
"http://dbpedia.org/ontology/abstract" : [ { "type" : "literal", "value" : "\u5185\u81D3\u9006\u4F4D\uFF08\u306A\u3044\u305E\u3046\u304E\u3083\u304F\u3044\u3001Situs inversus\uFF09\u306F\u3001\u5185\u81D3\u306E\u4E00\u90E8\u914D\u7F6E\u304C\u3001\u93E1\u306B\u6620\u3057\u305F\u3088\u3046\u306B\u53CD\u5BFE\u306B\u306A\u308B\u75C7\u72B6\u3092\u3044\u3046\u3002\u5168\u3066\u304C\u53CD\u8EE2\u3057\u3066\u3044\u308B\u5834\u5408\u306F\u5B8C\u5168\u5185\u81D3\u9006\u4F4D\u3068\u306A\u308B\u3002 \u307E\u305F\u3001\u5FC3\u81D3\u306A\u3069\u3001\u975E\u5BFE\u79F0\u3067\u3042\u308B\u81D3\u5668\u304C\u5DE6\u53F3\u5BFE\u79F0\u306B\u306A\u308B\u75C7\u72B6(\u6240\u8B02\u3001\u53F3\u5FC3\u81D3)\u306F\u3001\u5185\u81D3\u932F\u4F4D\uFF08Situs ambiguus\u3001\u30D8\u30C6\u30ED\u30BF\u30AD\u30B7\u30FC heterotaxy\u3068\u3082\uFF09\u3068\u3057\u3066\u533A\u5225\u3055\u308C\u308B\u3002 \u5FC3\u81D3\u306E\u307F\u3001\u307E\u305F\u306F\u5185\u81D3\u304C\u3059\u3079\u3066\u5DE6\u53F3\u9006\u306B\u914D\u7F6E\u3055\u308C\u3066\u3044\u308B\u3060\u3051\u3067\u3042\u308C\u3070\u6A5F\u80FD\u7684\u306B\u306F\u554F\u984C\u306A\u3044\u304C\u30011\u90E8\u306E\u81D3\u5668\u306E\u307F\u306E\u9006\u4F4D\u3067\u3042\u308B\u5834\u5408\u306F\u5947\u5F62\u3084\u75C5\u6C17\u3082\u591A\u304F\u3001\u624B\u8853\u3059\u308B\u4E8B\u306B\u306A\u308B\u4E8B\u304C\u591A\u3044\u3002 \u4F46\u3057\u3001\u307B\u3068\u3093\u3069\u306E\u533B\u5E2B\u304C\u9006\u4F4D\u306E\u60A3\u8005\u306E\u8A3A\u7642\u7D4C\u9A13\u3092\u6301\u305F\u306A\u3044\u305F\u3081\u3001\u75C5\u6C17\u3084\u4E8B\u6545\u306A\u3069\u306B\u3088\u308B\u8A3A\u7642\u3084\u624B\u8853\u306A\u3069\u3067\u3001\u5224\u65AD\u304C\u56F0\u96E3\u3068\u306A\u308B\u5834\u5408\u3082\u3042\u308B\u3002 \u5185\u81D3\u932F\u4F4D\u306B\u3082\u5FC3\u6A5F\u80FD\u4E0D\u5168\u306A\u3069\u91CD\u7BE4\u306A\u75C7\u72B6\u304C\u73FE\u308C\u308B\u3053\u3068\u304C\u591A\u3044\u3002\u4E73\u515022000\u4EBA\u306B1\u4EBA\u306E\u5272\u5408\u3067\u767A\u751F\u3059\u308B\u304C\u3001\u5FC3\u81D3\u306E\u307B\u304B\u4ED6\u306E\u81D3\u5668\u306B\u3064\u306A\u304C\u308B\u8840\u7BA1\u304C\u591A\u304B\u3063\u305F\u308A\u5C11\u306A\u304B\u3063\u305F\u308A\u3059\u308B\u305F\u3081\u3001\u5148\u5929\u6027\u306E\u91CD\u3044\u5FC3\u81D3\u75BE\u60A3\u306A\u3069\u3092\u4F34\u3046\u3053\u3068\u304C\u591A\u304F\u30015\u6B73\u307E\u3067\u751F\u5B58\u3067\u304D\u308B\u306E\u306F5 - 13%\u7A0B\u5EA6\u3068\u3055\u308C\u3066\u3044\u308B\u3002" , "lang" : "ja" } ,
{ "type" : "literal", "value" : "\u0623\u062D\u0634\u0627\u0621 \u0645\u0639\u0643\u0648\u0633\u0629 \u0627\u0644\u0645\u0648\u0636\u0639 \u0623\u0648 \u0627\u0644\u0627\u0646\u0639\u0643\u0627\u0633 \u0627\u0644\u062C\u0630\u0639\u064A \u0623\u0648 \u0627\u0646\u0642\u0644\u0627\u0628 \u0648\u0636\u0639 \u0627\u0644\u0623\u062D\u0634\u0627\u0621 (\u0628\u0627\u0644\u0625\u0646\u062C\u0644\u064A\u0632\u064A\u0629: Situs inversus) \u0647\u0648 \u062D\u0627\u0644\u0629 \u062E\u0650\u0644\u0642\u064A\u0629 \u064A\u062A\u0645 \u0641\u064A\u0647\u0627 \u0639\u0643\u0633 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062D\u0634\u0648\u064A\u0629 \u0627\u0644\u0631\u0626\u064A\u0633\u064A\u0629 \u0645\u0646 \u0645\u0648\u0627\u0642\u0639\u0647\u0627 \u0627\u0644\u0637\u0628\u064A\u0639\u064A\u0629. \u0648\u0639\u0644\u0649 \u0627\u0644\u0631\u063A\u0645 \u0645\u0646 \u0634\u064A\u0648\u0639 \u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u0642\u0644\u0628\u064A\u0629 \u0641\u064A \u0647\u0630\u0647 \u0627\u0644\u062D\u0627\u0644\u0629\u060C \u0644\u0643\u0646 \u0645\u0639\u0638\u0645 \u0627\u0644\u0630\u064A\u0646 \u064A\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u0623\u062D\u0634\u0627\u0621 \u0645\u0642\u0644\u0648\u0628\u0629 \u0627\u0644\u0645\u0648\u0636\u0639 \u0644\u064A\u0633 \u0644\u062F\u064A\u0647\u0645 \u0623\u064A \u0623\u0639\u0631\u0627\u0636 \u0637\u0628\u064A\u0629 \u0623\u0648 \u0645\u0636\u0627\u0639\u0641\u0627\u062A \u0646\u0627\u062C\u0645\u0629 \u0639\u0646 \u0647\u0630\u0647 \u0627\u0644\u062D\u0627\u0644\u0629\u060C \u062D\u062A\u0649 \u0623\u0646\u0647\u0627 \u0644\u0645 \u062A\u064F\u0634\u062E\u064E\u0651\u0635 \u062D\u062A\u0649 \u0638\u0647\u0648\u0631 \u0627\u0644\u0637\u0628 \u0627\u0644\u062D\u062F\u064A\u062B. \u0648\u064F\u062C\u0650\u062F \u0627\u0644\u0627\u0646\u0639\u0643\u0627\u0633 \u0627\u0644\u062C\u0630\u0639\u064A \u0641\u064A \u062D\u0648\u0627\u0644\u064A 0.01% \u0645\u0646 \u0627\u0644\u0628\u0634\u0631\u060C \u0623\u0648 \u0641\u064A \u062D\u0648\u0627\u0644\u064A \u0634\u062E\u0635 \u0645\u0646 \u0643\u0644 10,000. \u0641\u064A \u0627\u0644\u062D\u0627\u0644\u0629 \u0627\u0644\u0623\u0643\u062B\u0631 \u0634\u064A\u0648\u0639\u064B\u0627\u060C \u0627\u0644\u0627\u0646\u0639\u0643\u0627\u0633 \u0627\u0644\u062C\u0630\u0639\u064A \u0643\u0644\u064A\u064B\u0627\u060C \u064A\u0643\u0648\u0646 \u0647\u0646\u0627\u0643 \u062A\u0628\u062F\u064A\u0644 \u0643\u0627\u0645\u0644 \u0644\u062C\u0645\u064A\u0639 \u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u0628\u0637\u0646. \u0644\u0627 \u064A\u0643\u0648\u0646 \u0627\u0644\u0642\u0644\u0628 \u0641\u064A \u0645\u0648\u0636\u0639\u0647 \u0627\u0644\u0645\u0639\u062A\u0627\u062F \u0623\u064A\u0633\u0631 \u0627\u0644\u0635\u062F\u0631 \u0648\u0644\u0643\u0646 \u0639\u0644\u0649 \u0627\u0644\u064A\u0645\u064A\u0646\u060C \u0648\u0647\u064A \u062D\u0627\u0644\u0629 \u062A\u0639\u0631\u0641 \u0628\u0627\u0633\u0645 \u0642\u0644\u0628\u064C \u064A\u0645\u064A\u0646\u064A\u0651. \u0648\u0644\u0623\u0646 \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u064A\u0646 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0644\u0627 \u062A\u062A\u063A\u064A\u0631\u060C \u0641\u0644\u0627 \u064A\u0639\u0627\u0646\u064A \u0627\u0644\u0623\u0634\u062E\u0627\u0635 \u0645\u0646 \u0623\u064A \u0623\u0639\u0631\u0627\u0636 \u0623\u0648 \u0645\u0636\u0627\u0639\u0641\u0627\u062A \u0637\u0628\u064A\u0629\u060C \u0639\u0644\u0649 \u0627\u0644\u0631\u063A\u0645 \u0645\u0646 \u0648\u062C\u0648\u0628 \u062A\u0639\u0631\u064A\u0641 \u0648\u062A\u062D\u0630\u064A\u0631 \u0627\u0644\u0637\u0627\u0642\u0645 \u0627\u0644\u0637\u0628\u064A \u0641\u064A \u062D\u0627\u0644\u0627\u062A \u0627\u0644\u0637\u0648\u0627\u0631\u0626 \u0645\u0646 \u0623\u0646 \u0627\u0644\u0623\u0639\u0636\u0627\u0621 \u0627\u0644\u062F\u0627\u062E\u0644\u064A\u0629 \u0644\u0644\u0645\u0631\u064A\u0636 \u0645\u0646\u0639\u0643\u0633\u0629 \u0639\u0646 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{ "type" : "literal", "value" : "Situs inversus (lat. invertierte Lage) ist der medizinische Ausdruck f\u00FCr das Vollbild einer Heterotaxie, eine seltene, an sich nicht krankhafte Besonderheit der Anatomie, bei der sich die einzelnen Organe spiegelverkehrt jeweils auf der anderen Seite des K\u00F6rpers befinden. Das Antonym ist der Situs solitus, also die normgerechte Position der Organe im K\u00F6rper. Synonyme des Situs inversus sind: Inversio viscerum, Situs inversus viscerum, Situs inversus totalis, Situs perversus, Situs transversus, Situs rarior, Situs transversus viscerum, Situs oppositus, Situs inversus completus. Beim Situs inversus partialis sind nur entweder die Thoraxorgane (also die Herzh\u00E4lften und die Lungenfl\u00FCgel) oder die Bauchorgane spiegelbildlich quer vertauscht. Beim Situs inversus incompletus besteht keine Dextrokardie. Beim seltenen Situs inversus viscerum specularis ist nur einer von beiden eineiigen Zwillingen betroffen. Der Situs ambiguus bildet einen dritten Typ des Organsitus, also weder Situs inversus noch Situs solitus. Alle diese Lagebezeichnungen sind nicht in den offiziellen Listen der medizinischen Nomenklatur enthalten. In Analogie zur Chemie spricht man beim Situs inversus auch von einer Chiralit\u00E4t der inneren Organe. Bei keinem h\u00F6heren Lebewesen f\u00FChrt eine Drehspiegelung zur Selbstabbildung, wohl aber eine Achsenspiegelung. Diese Lebewesen sind asymmetrisch aufgebaut. Die betroffenen Zwillinge, von denen einer einen Situs inversus viscerum specularis hat, k\u00F6nnten dagegen durch eine Drehspiegelung, nicht aber durch eine Achsenspiegelung, mit dem jeweils anderen Geschwister (wie die zueinander symmetrischen H\u00E4nde, F\u00FC\u00DFe oder Ohren eines Menschen) zur Deckung gebracht werden." , "lang" : "de" } ,
{ "type" : "literal", "value" : "Situs inversus (also called situs transversus or oppositus) is a congenital condition in which the major visceral organs are reversed or mirrored from their normal positions. The normal arrangement of internal organs is known as situs solitus. Although cardiac problems are more common, many people with situs inversus have no medical symptoms or complications resulting from the condition, and until the advent of modern medicine, it was usually undiagnosed. Situs inversus is found in about 0.01% of the population, or about 1 person in 10,000. In the most common situation, situs inversus totalis, it involves complete transposition (right to left reversal) of all of the viscera. The heart is not in its usual position in the left chest, but is on the right, a condition known as dextrocardia (literally, \"right-hearted\"). Because the relationship between the organs is not changed, most people with situs inversus have no associated medical symptoms or complications. An uncommon form of situs inversus is isolated levocardia, in which the position of the heart is not mirrored alongside the other organs. Isolated levocardia carries a risk of heart defects, and so patients with the condition may require surgery to correct them. In rarer cases such as situs ambiguus or heterotaxy, situs cannot be determined. In these patients, the liver may be midline, the spleen absent or multiple, and the bowel malrotated. Often, structures are duplicated or absent altogether. This is more likely to cause medical problems than situs inversus totalis." , "lang" : "en" } ,
{ "type" : "literal", "value" : "\uB0B4\uC7A5 \uC5ED\uC704\uC99D(\u5167\u81DF\u9006\u4F4D\u75C7, situs inversus, situs transversus, oppositus)\uC740 \uC8FC\uC694 \uAE30\uAD00\uB4E4\uC774 \uC815\uC0C1 \uC704\uCE58\uAC00 \uC544\uB2CC \uBC18\uB300\uB85C, \uC989 \uAC70\uC6B8 \uC704\uCE58\uC5D0 \uC788\uB294 \uC120\uCC9C\uC131 \uC9C8\uBCD1\uC774\uB2E4." , "lang" : "ko" } ,
{ "type" : "literal", "value" : "El Situs inversus es una extra\u00F1a malformaci\u00F3n gen\u00E9tica que puede afectar a varios \u00F3rganos y tiene un car\u00E1cter gen\u00E9tico. Consiste en una alineaci\u00F3n err\u00F3nea de los \u00F3rganos dentro del cuerpo, coloc\u00E1ndolos del lado opuesto (imagen de espejo). El t\u00E9rmino situs inversus es la forma abreviada de la frase en Lat\u00EDn, situs inversus viscerum, significando posici\u00F3n invertida de los \u00F3rganos internos. La Dextrocardia (el coraz\u00F3n situado en la parte derecha del t\u00F3rax) fue descrita por primera vez por en 1643. Sin embargo, situs inversus fue descrito un siglo m\u00E1s tarde por Matthew Baillie. Generalmente va asociado a otras malformaciones, tales como poliesplenia, S\u00EDndrome de Kartagener, etc. Suele representar un serio riesgo para la vida pues en la mayor\u00EDa de los casos va acompa\u00F1ado de malformaciones card\u00EDacas (v\u00E9ase Dextrocardia). Tambi\u00E9n representa un problema en cuanto a la presentaci\u00F3n de s\u00EDntomas de algunas enfermedades, por ejemplo la apendicitis en un paciente con situs inversus presenta el dolor en el lado izquierdo, al igual que en el caso de un infarto al coraz\u00F3n en el cual el dolor caracter\u00EDstico se ubica en el brazo derecho. Lo m\u00E1s recomendable, en el caso de que se opte por una cirug\u00EDa, es recopilar la mayor cantidad de informaci\u00F3n posible, debido a posibles complicaciones que pueden no haber sido descubiertas con ex\u00E1menes demasiados superficiales. Es posible que el intercambio de lateralidad cerebral psicomotriz sea tambi\u00E9n un caso com\u00FAn de Situs Inversus. Se sabe que la \"discinesia ciliar primaria\" genera con frecuencia situs inversus. Adem\u00E1s de los cilios con el patr\u00F3n de microt\u00FAbulos 9+2 se han encontrado otro tipo ciliar con una organizaci\u00F3n microtubular 9+0. Los cilios con este patr\u00F3n carecen de un par central de microt\u00FAbulos. Estos cilios aparecen en una gran variedad de c\u00E9lulas y reciben el nombre de monocilios o cilios primarios, porque cada c\u00E9lula solamente posee uno solo. Antes los monociolios se clasificaban como vestigios no funcinales de cilios 9+2 resultante de un desarrollo an\u00F3malo. Sin embargo, varios estudios recientes indican que algunos monocilios son m\u00F3viles y cumplen una funci\u00F3n en el desarrollo embrionario inicial al generar la simetr\u00EDa bilateral (derecha-izquierda) de los \u00F3rganos internos. Estos monocilios contienen prote\u00EDnas motoras asociadas con los microt\u00FAbulos (dine\u00EDnas) y son capaces de realizar un movimiento rotatorio. Durante la gastrulaci\u00F3n en la superficie ventral del disco embrionario bilaminar se ha observado una rotaci\u00F3n de los monocilios en el sentido de las agujas del reloj. El movimiento de los monocilios en la regi\u00F3n conocida como nodo o n\u00F3dulo primario genera un flujo hacia la izquierda o \u201Cflujo nodal\u201D. Este flujo es detectado por receptores sensitivos en el lado izquierdo del cuerpo; luego esos receptores inician mecanismos de se\u00F1alizaci\u00F3n que difieren de los del lado derecho del embri\u00F3n. Cuando los cilios nodales son inm\u00F3viles o el flujo nodal no se produce, esto conduce a una ubicaci\u00F3n aleatoria de los \u00F3rganos internos del cuerpo. Por lo tanto la discinesia ciliar primaria (s\u00EDndrome de los cilios inm\u00F3viles) con frecuencia genera situs inversus.\u200B" , "lang" : "es" } ,
{ "type" : "literal", "value" : "Il situs inversus \u00E8 una condizione congenita dove gli organi sono invertiti in modo speculare rispetto alla loro usuale posizione, che \u00E8 detta invece , ed \u00E8 caratterizzata da destrocardia, fegato a sinistra e milza a destra. La dineina \u00E8 la proteina determinante per l'induzione della lateralizzazione: essa \u00E8 infatti costituente dei flagelli che creano, nell'embrione, le correnti attraverso le quali gli ormoni inerenti allo sviluppo dell'individuo vengono direzionati secondo un ordine preciso. Se il gene codificante la proteina, e la proteina stessa, sono funzionanti, l'organismo sar\u00E0 \"destro\". Altrimenti si ha il situs inversus, che pu\u00F2 essere globale, speculare (situs viscerum inversus), o parziale (situs ambiguus). La prevalenza del situs inversus varia all'interno delle diverse popolazioni, ma \u00E8 comunque meno di 1 caso ogni 10 000 persone." , "lang" : "it" } ,
{ "type" : "literal", "value" : "\u81DF\u5668\u9006\u4F4D\uFF08situs inversus\uFF09\u4EA6\u7A31\u5167\u81DF\u53CD\u4F4D\uFF0C\u662F\u4E00\u7A2E\u5148\u5929\u6027\u7684\u7D50\u69CB\u7F3A\u9677\uFF0C\u75C7\u72C0\u662F\u60A3\u8005\u7684\u5167\u81DF\u5404\u5668\u5B98\u7684\u4F4D\u7F6E\u8207\u4E00\u822C\u4EBA\u6B63\u597D\u5DE6\u53F3\u76F8\u53CD\uFF08\u93E1\u50CF\u5C0D\u7A31\uFF09\uFF0C\u8B6C\u5982\u60A3\u8005\u7684\u5FC3\u81DF\u4F4D\u5728\u53F3\u624B\u908A\uFF0C\u809D\u81DF\u4F4D\u5728\u5DE6\u624B\u908A\u3002\u9019\u7A2E\u5148\u5929\u7F3A\u9677\u73FE\u8C61\u8F03\u7F55\u898B\uFF0C\u5927\u7EA6\u767E\u842C\u4EBA\u88E1\u624D\u6709\u4E00\u500B\uFF081/1000000\uFF09\u3002 \u81DF\u5668\u9006\u4F4D\u4E00\u822C\u8207\u5E38\u67D3\u8272\u9AD4\u96B1\u6027\u57FA\u56E0\u6709\u95DC\uFF0C\u6B64\u5916\uFF0C\u60A3\u6709\u5148\u5929\u6027\u5FC3\u81DF\u75C5\u60A3\u75C5\u7684\u6BD4\u7387\u76F8\u5C0D\u504F\u9AD8\uFF0C\u60A3\u8005\u7684\u5065\u5EB7\u72C0\u6CC1\u4E00\u822C\u8207\u666E\u901A\u4EBA\u7121\u751A\u660E\u986F\u5340\u5225\uFF0C\u8A31\u591A\u60A3\u8005\u662F\u4E00\u76F4\u5230\u81EA\u5DF1\u7684X\u5149\u7247\u624D\u77E5\u9053\u81EA\u5DF1\u7684\u5167\u81DF\u4F4D\u7F6E\u8207\u5176\u4ED6\u4EBA\u4E0D\u4E00\u6A23\uFF0C\u4E14\u5448\u73FE\u93E1\u50CF\u5C0D\u7A31\u73FE\u8C61\u3002" , "lang" : "zh" } ,
{ "type" : "literal", "value" : "Situs Inversus (tamb\u00E9m conhecido por situs transversus ou situs oppositus) \u00E9 uma condi\u00E7\u00E3o em que alguns \u00F3rg\u00E3os ficam localizados no lado oposto em rela\u00E7\u00E3o ao local onde eles seriam normalmente encontrados. Basicamente consiste numa invers\u00E3o de posi\u00E7\u00E3o dos \u00F3rg\u00E3os dentro do corpo, ficando localizados do lado oposto (como uma imagem de espelho). Cerca de 0,01% das pessoas s\u00E3o atingidas por essa anomalia, que \u00E9 uma heran\u00E7a transmitida por genes autoss\u00F4micos recessivos, sem predile\u00E7\u00E3o por sexo. Em muitos casos, a invers\u00E3o de \u00F3rg\u00E3os n\u00E3o diminui a expectativa de vida da pessoa, nem prejudica sua qualidade de vida. Assim, algumas pessoas nem sabem que apresentam o problema, e s\u00F3 acabam descobrindo acidentalmente." , "lang" : "pt" } ,
{ "type" : "literal", "value" : "\u0397 \u03B1\u03BD\u03B1\u03C3\u03C4\u03C1\u03BF\u03C6\u03AE \u03BF\u03C1\u03B3\u03AC\u03BD\u03C9\u03BD (situs inversus, \u03B1\u03C0\u03BF\u03BA\u03B1\u03BB\u03B5\u03AF\u03C4\u03B1\u03B9 \u03B5\u03C0\u03AF\u03C3\u03B7\u03C2 situs transversus \u03AE oppositus) \u03B5\u03AF\u03BD\u03B1\u03B9 \u03C3\u03C5\u03B3\u03B3\u03B5\u03BD\u03AE\u03C2 \u03BA\u03B1\u03C4\u03AC\u03C3\u03C4\u03B1\u03C3\u03B7, \u03C3\u03C4\u03B7\u03BD \u03BF\u03C0\u03BF\u03AF\u03B1 \u03C4\u03B1 \u03BA\u03CD\u03C1\u03B9\u03B1 \u03C3\u03C0\u03BB\u03B1\u03C7\u03BD\u03B9\u03BA\u03AC \u03CC\u03C1\u03B3\u03B1\u03BD\u03B1 \u03B1\u03BD\u03C4\u03B9\u03C3\u03C4\u03C1\u03AD\u03C6\u03BF\u03BD\u03C4\u03B1\u03B9 \u03AE \u03B1\u03BD\u03C4\u03B9\u03BA\u03B1\u03C4\u03BF\u03C0\u03C4\u03C1\u03AF\u03B6\u03BF\u03BD\u03C4\u03B1\u03B9 \u03B1\u03C0\u03CC \u03C4\u03B9\u03C2 \u03BA\u03B1\u03BD\u03BF\u03BD\u03B9\u03BA\u03AD\u03C2 \u03C4\u03BF\u03C5\u03C2 \u03B8\u03AD\u03C3\u03B5\u03B9\u03C2. \u0397 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\u03C3\u03C4\u03B1 10.000. \u03A3\u03C4\u03B7\u03BD \u03C0\u03B9\u03BF \u03C3\u03C5\u03BD\u03B7\u03B8\u03B9\u03C3\u03BC\u03AD\u03BD\u03B7 \u03BA\u03B1\u03C4\u03AC\u03C3\u03C4\u03B1\u03C3\u03B7, \u03B7 \u03BF\u03BB\u03B9\u03BA\u03AE \u03B1\u03BD\u03B1\u03C3\u03C4\u03C1\u03BF\u03C6\u03AE \u03BF\u03C1\u03B3\u03AC\u03BD\u03C9\u03BD (situs inversus totalis), \u03C0\u03B5\u03C1\u03B9\u03BB\u03B1\u03BC\u03B2\u03AC\u03BD\u03B5\u03B9 \u03C0\u03BB\u03AE\u03C1\u03B7 \u03BC\u03B5\u03C4\u03B1\u03C6\u03BF\u03C1\u03AC (\u03B1\u03BD\u03C4\u03B9\u03C3\u03C4\u03C1\u03BF\u03C6\u03AE \u03B1\u03C0\u03CC \u03B4\u03B5\u03BE\u03B9\u03AC \u03C0\u03C1\u03BF\u03C2 \u03C4\u03B1 \u03B1\u03C1\u03B9\u03C3\u03C4\u03B5\u03C1\u03AC) \u03CC\u03BB\u03C9\u03BD \u03C4\u03C9\u03BD \u03C3\u03C0\u03BB\u03AC\u03C7\u03BD\u03C9\u03BD . \u0397 \u03BA\u03B1\u03C1\u03B4\u03B9\u03AC \u03B4\u03B5\u03BD \u03B2\u03C1\u03AF\u03C3\u03BA\u03B5\u03C4\u03B1\u03B9 \u03C3\u03C4\u03B7 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\u03AC\u03BB\u03BB\u03B1 \u03CC\u03C1\u03B3\u03B1\u03BD\u03B1. \u0397 \u03B1\u03C0\u03BF\u03BC\u03BF\u03BD\u03C9\u03BC\u03AD\u03BD\u03B7 \u03BB\u03B5\u03B2\u03BF\u03BA\u03B1\u03C1\u03B4\u03AF\u03B1 \u03B5\u03BD\u03AD\u03C7\u03B5\u03B9 \u03BA\u03AF\u03BD\u03B4\u03C5\u03BD\u03BF \u03BA\u03B1\u03C1\u03B4\u03B9\u03B1\u03BA\u03CE\u03BD \u03B5\u03BB\u03B1\u03C4\u03C4\u03C9\u03BC\u03AC\u03C4\u03C9\u03BD \u03BA\u03B1\u03B9 \u03AD\u03C4\u03C3\u03B9 \u03BF\u03B9 \u03B1\u03C3\u03B8\u03B5\u03BD\u03B5\u03AF\u03C2 \u03BC\u03B5 \u03C4\u03B7\u03BD \u03C0\u03AC\u03B8\u03B7\u03C3\u03B7 \u03BC\u03C0\u03BF\u03C1\u03B5\u03AF \u03BD\u03B1 \u03C7\u03C1\u03B5\u03B9\u03B1\u03C3\u03C4\u03BF\u03CD\u03BD \u03C7\u03B5\u03B9\u03C1\u03BF\u03C5\u03C1\u03B3\u03B9\u03BA\u03AE \u03B5\u03C0\u03AD\u03BC\u03B2\u03B1\u03C3\u03B7 \u03B3\u03B9\u03B1 \u03BD\u03B1 \u03C4\u03B1 \u03B4\u03B9\u03BF\u03C1\u03B8\u03CE\u03C3\u03BF\u03C5\u03BD. \u03A3\u03B5 \u03C3\u03C0\u03B1\u03BD\u03B9\u03CC\u03C4\u03B5\u03C1\u03B5\u03C2 \u03C0\u03B5\u03C1\u03B9\u03C0\u03C4\u03CE\u03C3\u03B5\u03B9\u03C2 \u03CC\u03C0\u03C9\u03C2 \u03B7 \u03B1\u03C3\u03B1\u03C6\u03AE\u03C2 \u03B1\u03BD\u03B1\u03C3\u03C4\u03C1\u03BF\u03C6\u03AE \u03BF\u03C1\u03B3\u03AC\u03BD\u03C9\u03BD \u03AE \u03B7 \u03B5\u03C4\u03B5\u03C1\u03BF\u03C4\u03B1\u03BE\u03AF\u03B1, \u03B7 \u03B1\u03BD\u03B1\u03C3\u03C4\u03C1\u03BF\u03C6\u03AE \u03B4\u03B5\u03BD \u03BC\u03C0\u03BF\u03C1\u03B5\u03AF \u03BD\u03B1 \u03C0\u03C1\u03BF\u03C3\u03B4\u03B9\u03BF\u03C1\u03B9\u03C3\u03C4\u03B5\u03AF. \u03A3\u03B5 \u03B1\u03C5\u03C4\u03BF\u03CD\u03C2 \u03C4\u03BF\u03C5\u03C2 \u03B1\u03C3\u03B8\u03B5\u03BD\u03B5\u03AF\u03C2, \u03C4\u03BF \u03AE\u03C0\u03B1\u03C1 \u03BC\u03C0\u03BF\u03C1\u03B5\u03AF \u03BD\u03B1 \u03B5\u03AF\u03BD\u03B1\u03B9 \u03BC\u03B5\u03C3\u03B1\u03AF\u03B1 \u03B3\u03C1\u03B1\u03BC\u03BC\u03AE, \u03BF \u03C3\u03C0\u03BB\u03AE\u03BD\u03B1\u03C2 \u03BD\u03B1 \u03B1\u03C0\u03BF\u03C5\u03C3\u03B9\u03AC\u03B6\u03B5\u03B9 \u03AE \u03BD\u03B1 \u03B5\u03AF\u03BD\u03B1\u03B9 \u03C0\u03BF\u03BB\u03BB\u03B1\u03C0\u03BB\u03CC\u03C2 \u03BA\u03B1\u03B9 \u03C4\u03BF \u03AD\u03BD\u03C4\u03B5\u03C1\u03BF \u03BD\u03B1 \u03AD\u03C7\u03B5\u03B9 \u03C5\u03C0\u03BF\u03C3\u03C4\u03B5\u03AF \u03BA\u03B1\u03BA\u03AF\u03B1. \u03A3\u03C5\u03C7\u03BD\u03AC, \u03BF\u03B9 \u03B4\u03BF\u03BC\u03AD\u03C2 \u03B1\u03BD\u03C4\u03B9\u03B3\u03C1\u03AC\u03C6\u03BF\u03BD\u03C4\u03B1\u03B9 \u03AE \u03B1\u03C0\u03BF\u03C5\u03C3\u03B9\u03AC\u03B6\u03BF\u03C5\u03BD \u03B5\u03BD\u03C4\u03B5\u03BB\u03CE\u03C2. \u0391\u03C5\u03C4\u03CC \u03B5\u03AF\u03BD\u03B1\u03B9 \u03C0\u03B9\u03BF \u03C0\u03B9\u03B8\u03B1\u03BD\u03CC \u03BD\u03B1 \u03C0\u03C1\u03BF\u03BA\u03B1\u03BB\u03AD\u03C3\u03B5\u03B9 \u03B9\u03B1\u03C4\u03C1\u03B9\u03BA\u03AC \u03C0\u03C1\u03BF\u03B2\u03BB\u03AE\u03BC\u03B1\u03C4\u03B1 \u03B1\u03C0\u03CC \u03C4\u03B7\u03BD \u03BF\u03BB\u03B9\u03BA\u03AE \u03B1\u03BD\u03B1\u03C3\u03C4\u03C1\u03BF\u03C6\u03AE \u03BF\u03C1\u03B3\u03AC\u03BD\u03C9\u03BD." , "lang" : "el" } ,
{ "type" : "literal", "value" : "Situs inversus (ICD-10 Q89.3) is een zeldzame verstoring van de links-rechtsconfiguratie binnen het lichaam. Met andere woorden, de organen zijn in spiegelbeeld gepositioneerd in het lichaam. De lever zit dan bijvoorbeeld links in plaats van rechts. De normale positionering van de organen heet situs solitus. Er kan sprake zijn van een totale situs inversus (situs inversus totalis) of een parti\u00EBle. Het komt voor bij minder dan 1 op de 10.000 mensen. De verstoring gaat in ongeveer een kwart van de gevallen gepaard met structurele afwijkingen in de cilia (trilhaartjes). Dit heet het syndroom van Kartagener. Dit leidt tot een verstoring van het mucociliaire transport (het transport van slijm over de slijmvliezen, dat door de cilia wordt verzorgd). Voor de desbetreffende personen is het belangrijk dat hun artsen dit weten en dat zij dit ook doorgeven aan hun omgeving, dit voor noodgevallen. Bij het maken van een ECG moeten er kabeltjes verwisseld worden vanwege de in spiegelbeeld gepositioneerde organen, en dan met name het hart." , "lang" : "nl" } ,
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{ "type" : "literal", "value" : "Situs inversus, kortform av det latinska situs inversus viscerum, \u00E4ven situs transverses \u00E4r ett \u00E4rftligt tillst\u00E5nd med omv\u00E4nd eller spegelv\u00E4nd plats f\u00F6r organen i br\u00F6st och bukh\u00E5la. Hj\u00E4rtat och magen \u00E4r placerade till h\u00F6ger och mj\u00E4lten kan vara p\u00E5 h\u00F6ger sida av buken, medan lever, gallbl\u00E5sa och appendix ligger till v\u00E4nster. Lungor, lymfk\u00E4rl, nerver och tarmar \u00E4r omv\u00E4nda j\u00E4mf\u00F6rt med det normala. Personer som f\u00F6ds med situs inversus lever sannolikt ett normalt liv, om organen i \u00F6vrigt \u00E4r utan anm\u00E4rkning. Ibland uppt\u00E4cks avvikelsen f\u00F6rst vid l\u00E4karunders\u00F6kning av andra sk\u00E4l. Helt spegelv\u00E4nda organ utan missbildningar kallas situs inversus totalis. Alla f\u00F6r\u00E4ndringar mellan det och normal placering och asymmetri av organen (situs solitus) ing\u00E5r i heterotaxisyndromet. Den h\u00E4r artikeln \u00E4r helt eller delvis baserad p\u00E5 material fr\u00E5n norska Wikipedia (bokm\u00E5l/riksm\u00E5l), Situs inversus, 10 januari 2012." , "lang" : "sv" } ,
{ "type" : "literal", "value" : "Situs inversus (\u00E9galement appel\u00E9 situs transversus ou oppositus) est un terme de m\u00E9decine d\u00E9signant une anomalie cong\u00E9nitale dans laquelle les principaux visc\u00E8res et organes sont invers\u00E9s dans une position en miroir par rapport \u00E0 leur disposition normale (le plan sagittal). La disposition normale est appel\u00E9e . Elle est d\u00E9finie par la position des oreillettes : \u00E0 droite pour l'oreillette droite et \u00E0 gauche pour l'oreillette gauche. Dans le situs inversus, l'oreillette droite est \u00E0 gauche et l'oreillette gauche \u00E0 droite. Dans d'autres cas plus rares, le situs ne peut pas \u00EAtre d\u00E9termin\u00E9, affection connue sous le nom de situs ambiguus. Ces affections sont regroup\u00E9es sous le terme g\u00E9n\u00E9rique d'h\u00E9t\u00E9rotaxie. Le terme situs inversus est une abr\u00E9viation de la formule latine \u00AB situs inversus viscerum \u00BB, qui signifie \u00AB position invers\u00E9e des organes internes \u00BB. La dextrocardie (c\u0153ur situ\u00E9 sur le c\u00F4t\u00E9 droit de la cavit\u00E9 thoracique) a d'abord \u00E9t\u00E9 identifi\u00E9e par Marco Aurelio Severino en 1643. Toutefois, le situs inversus proprement dit n\u2019a \u00E9t\u00E9 d\u00E9crit pour la premi\u00E8re fois que plus d'un si\u00E8cle apr\u00E8s par Matthew Baillie. La pr\u00E9valence du situs inversus varie suivant les groupes de populations, mais est inf\u00E9rieure \u00E0 1 sur 10 000 personnes. Des recherches portant sur les mutations g\u00E9n\u00E9tiques associ\u00E9es ont \u00E9t\u00E9 effectu\u00E9es et certains g\u00E8nes isol\u00E9s, tel que DNAH5 (auparavant appel\u00E9 HL1, PCD, ou encore CILD3), responsable de la dyskin\u00E9sie ciliaire primitive qui est pr\u00E9sente dans 50 % des cas de situs inversus. Ce g\u00E8ne code une prot\u00E9ine : la cha\u00EEne lourde 5 de la dyn\u00E9ine axon\u00E9male. La dyn\u00E9ine a un r\u00F4le essentiel dans le fonctionnement des cils et des flagelles. Cependant, lors d\u2019un situs inversus, une mutation du g\u00E8ne DNAH5 va avoir des r\u00E9percussions sur la biochimie de la dyn\u00E9ine : souvent, la dyn\u00E9ine sera pr\u00E9sente en quantit\u00E9 insuffisante, ou ne fonctionnera pas correctement, par cons\u00E9quent les cils ne seront pas assez efficaces et ne pourront donc pas se mouvoir. Une carence en dyn\u00E9ines dans les cils des voies respiratoires est associ\u00E9e au syndrome de Kartagener. De plus, des cils immobiles ou dyskin\u00E9tiques lors du d\u00E9veloppement embryonnaire entra\u00EEnent une lat\u00E9ralisation al\u00E9atoire. Cela sugg\u00E8re que des mutations de DNAH5 interviendraient \u00E0 la fois dans la dyskin\u00E9sie ciliaire primitive et dans l\u2019h\u00E9t\u00E9rotaxie.D'autres g\u00E8nes sont associ\u00E9s au situs inversus comme DNAH11, DNAI1 et DNAI2." , "lang" : "fr" } ] ,
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