The 2013 CME Group Titleholders was the third CME Group Titleholders, a women's professional golf tournament and the season-ending event on the U.S.-based LPGA Tour. It was played November 21–24 at the Gold Course of Tiburón Golf Club in Naples, Florida. The top three finishers who were LPGA members from each official LPGA tournament, not otherwise qualified, earned a spot in the Titleholders. If tied, the player with the lower final round score qualified.