About: Butriptyline

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Butriptyline, sold under the brand name Evadyne among others, is a tricyclic antidepressant (TCA) that has been used in the United Kingdom and several other European countries for the treatment of depression but appears to no longer be marketed. Along with trimipramine, iprindole, and amoxapine, it has been described as an "atypical" or "second-generation" TCA due to its relatively late introduction and atypical pharmacology. It was very little-used compared to other TCAs, with the number of prescriptions dispensed only in the thousands.

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dbo:abstract
  • Butriptylin ist ein Arzneistoff aus der Gruppe der trizyklischen Antidepressiva. Vom Wirkmechanismus ähnelt es Amitriptylin. Es soll aber bei gleicher Dosis eine effektivere antidepressive Wirkung entfalten als Amitriptylin, ohne dabei mehr Nebenwirkungen zu haben.Die maximale Wirkung (Tmax) entfaltet es nach 2,6 (unretardiert) bis 7,5 Stunden (retardiert). Die Plasmahalbwertszeit liegt bei 20 Stunden. (de)
  • Butriptyline, sold under the brand name Evadyne among others, is a tricyclic antidepressant (TCA) that has been used in the United Kingdom and several other European countries for the treatment of depression but appears to no longer be marketed. Along with trimipramine, iprindole, and amoxapine, it has been described as an "atypical" or "second-generation" TCA due to its relatively late introduction and atypical pharmacology. It was very little-used compared to other TCAs, with the number of prescriptions dispensed only in the thousands. (en)
  • La butriptilina es un medicamento antidepresivo de la clase de tricíclicos de primera generación, con propiedades sedantes similares a la amitriptilina.​ En casos de sobredosis, la butriptilina puede causar la muerte del individuo.​ (es)
  • Butriptilina (evadene) é um antidepressivo tricíclico (ADT), que foi usado na Europa desde 1974. É um homólogo da amitriptilina. (pt)
dbo:alternativeName
  • Evadyne, others (en)
dbo:casNumber
  • 35941-65-2
  • 5585-73-9
dbo:chEBI
  • 135227
dbo:chEMBL
  • 2110816
dbo:drugbank
  • DB09016
dbo:fdaUniiCode
  • LIJ2H8658W
  • Z22441975X
dbo:kegg
  • D07601
dbo:pubchem
  • 21772
dbo:thumbnail
dbo:wikiPageExternalLink
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  • 19789 (xsd:nonNegativeInteger)
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  • 1078843289 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • N06 (en)
dbp:atcSuffix
  • AA15 (en)
dbp:bioavailability
  • ? (en)
dbp:c
  • 21 (xsd:integer)
dbp:casNumber
  • 5585 (xsd:integer)
  • 35941 (xsd:integer)
dbp:chebi
  • 135227 (xsd:integer)
dbp:chembl
  • 2110816 (xsd:integer)
dbp:chemspiderid
  • 20462 (xsd:integer)
dbp:chirality
dbp:drugbank
  • DB09016 (en)
dbp:eliminationHalfLife
  • 72000.0 (dbd:second)
dbp:h
  • 27 (xsd:integer)
dbp:index2Label
  • HCl (en)
dbp:iupacName
  • -3 (xsd:integer)
dbp:kegg
  • D07601 (en)
dbp:legalStatus
  • Rx-only (en)
dbp:metabolism
  • Hepatic (en)
dbp:metabolites
  • Norbutriptyline (en)
dbp:n
  • 1 (xsd:integer)
dbp:proteinBound
  • >90% (en)
dbp:pubchem
  • 21772 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • c1cc3cCCc2cC3CCCNC (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • ALELTFCQZDXAMQ-UHFFFAOYSA-N (en)
dbp:synonyms
  • AY-62014 (en)
dbp:title
dbp:titlestyle
  • background:#ccccff (en)
dbp:tradename
  • Evadyne, others (en)
dbp:unii
  • LIJ2H8658W (en)
  • Z22441975X (en)
dbp:verifiedfields
  • changed (en)
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  • 447573132 (xsd:integer)
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  • 200 (xsd:integer)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:comment
  • Butriptylin ist ein Arzneistoff aus der Gruppe der trizyklischen Antidepressiva. Vom Wirkmechanismus ähnelt es Amitriptylin. Es soll aber bei gleicher Dosis eine effektivere antidepressive Wirkung entfalten als Amitriptylin, ohne dabei mehr Nebenwirkungen zu haben.Die maximale Wirkung (Tmax) entfaltet es nach 2,6 (unretardiert) bis 7,5 Stunden (retardiert). Die Plasmahalbwertszeit liegt bei 20 Stunden. (de)
  • Butriptyline, sold under the brand name Evadyne among others, is a tricyclic antidepressant (TCA) that has been used in the United Kingdom and several other European countries for the treatment of depression but appears to no longer be marketed. Along with trimipramine, iprindole, and amoxapine, it has been described as an "atypical" or "second-generation" TCA due to its relatively late introduction and atypical pharmacology. It was very little-used compared to other TCAs, with the number of prescriptions dispensed only in the thousands. (en)
  • La butriptilina es un medicamento antidepresivo de la clase de tricíclicos de primera generación, con propiedades sedantes similares a la amitriptilina.​ En casos de sobredosis, la butriptilina puede causar la muerte del individuo.​ (es)
  • Butriptilina (evadene) é um antidepressivo tricíclico (ADT), que foi usado na Europa desde 1974. É um homólogo da amitriptilina. (pt)
rdfs:label
  • Butriptylin (de)
  • Butriptyline (en)
  • Butriptilina (es)
  • Butriptilina (pt)
rdfs:seeAlso
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
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