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In electrocardiography, during a cardiac cycle, once an action potential is initiated, there is a period of time that a new action potential cannot be initiated. This is termed the effective refractory period (ERP) of the tissue. This period is approximately equal to the absolute refractory period (ARP), it occurs because the fast sodium channels remain closed until the cell fully repolarizes.During this period, depolarization on adjacent cardiac muscles does not produce a new depolarization in the current cell as it has to refract back to phase 4 of the action potential before a new action potential can activate it. ERP acts as a protective mechanism and keeps the heart rate in check and prevents arrhythmias, and it helps coordinates muscle contraction. Anti-arrhythmic agents used for arr

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  • In electrocardiography, during a cardiac cycle, once an action potential is initiated, there is a period of time that a new action potential cannot be initiated. This is termed the effective refractory period (ERP) of the tissue. This period is approximately equal to the absolute refractory period (ARP), it occurs because the fast sodium channels remain closed until the cell fully repolarizes.During this period, depolarization on adjacent cardiac muscles does not produce a new depolarization in the current cell as it has to refract back to phase 4 of the action potential before a new action potential can activate it. ERP acts as a protective mechanism and keeps the heart rate in check and prevents arrhythmias, and it helps coordinates muscle contraction. Anti-arrhythmic agents used for arrhythmias usually prolong the ERP. For the treatment of atrial fibrillation, it is a problem that the prolongation of the ERP by these agents also affects the ventricles, which can induce other types of arrhythmias. (en)
  • El periodo refractario efectivo (ERP: Electric Refractory (Recovery) Period, por sus siglas en inglés. PRE en español.) es el intervalo de tiempo en el cual una célula excitable no puede volver a despolarizarse ni transmitir un nuevo potencial de acción a la siguiente célula. (es)
  • De refractaire periode is een tijd wanneer er geen tot weinig doorgiftekanalen aanwezig zijn in een zenuwcel. (nl)
  • In elettrocardiografia, durante il ciclo cardiaco, quando il potenziale d'azione si avvia, vi è un periodo di tempo nel quale un nuovo potenziale azione non può essere "riavviato". Questo è definito il periodo refrattario effettivo (PRE) del tessuto. Questo periodo è anche noto come periodo refrattario assoluto (PRA), che è successivo all'ingresso degli ioni calcio nel miocita. Durante questo periodo, non si può produrre una nuova depolarizzazione nelle cellule miocardiche se non si ritorna alla fase 4 del potenziale. Il PRE agisce come un meccanismo di protezione e mantiene la frequenza cardiaca sotto controllo, previene aritmie e aiuta a coordinare la contrazione muscolare. I farmaci antiaritmici utilizzati per le aritmie di solito prolungano il periodo refrattario effettivo. (it)
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  • El periodo refractario efectivo (ERP: Electric Refractory (Recovery) Period, por sus siglas en inglés. PRE en español.) es el intervalo de tiempo en el cual una célula excitable no puede volver a despolarizarse ni transmitir un nuevo potencial de acción a la siguiente célula. (es)
  • De refractaire periode is een tijd wanneer er geen tot weinig doorgiftekanalen aanwezig zijn in een zenuwcel. (nl)
  • In electrocardiography, during a cardiac cycle, once an action potential is initiated, there is a period of time that a new action potential cannot be initiated. This is termed the effective refractory period (ERP) of the tissue. This period is approximately equal to the absolute refractory period (ARP), it occurs because the fast sodium channels remain closed until the cell fully repolarizes.During this period, depolarization on adjacent cardiac muscles does not produce a new depolarization in the current cell as it has to refract back to phase 4 of the action potential before a new action potential can activate it. ERP acts as a protective mechanism and keeps the heart rate in check and prevents arrhythmias, and it helps coordinates muscle contraction. Anti-arrhythmic agents used for arr (en)
  • In elettrocardiografia, durante il ciclo cardiaco, quando il potenziale d'azione si avvia, vi è un periodo di tempo nel quale un nuovo potenziale azione non può essere "riavviato". Questo è definito il periodo refrattario effettivo (PRE) del tessuto. Questo periodo è anche noto come periodo refrattario assoluto (PRA), che è successivo all'ingresso degli ioni calcio nel miocita. Durante questo periodo, non si può produrre una nuova depolarizzazione nelle cellule miocardiche se non si ritorna alla fase 4 del potenziale. (it)
rdfs:label
  • Periodo refractario efectivo (es)
  • Effective refractory period (en)
  • Periodo refrattario effettivo (it)
  • Refractaire periode (neurobiologie) (nl)
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