About: Ixabepilone

Property	Value
dbo:abstract	يُعد عقار إكسابيبيلون (المعروف أيضًا باسم azaepothilone B، والذي يحمل الاسم الرمزي BMS-247550 )دواءًا صيدلانيًا طورته شركة بريستول-مايرز سكويب كدواء علاجي كيميائي للسرطان. (ar) Ixabepilone (INN; also known as azaepothilone B, codenamed BMS-247550) is a pharmaceutical drug developed by Bristol-Myers Squibb as a chemotherapeutic medication for cancer. (en) Iksabepilon – organiczny związek chemiczny, półsyntetyczny analog epotilonu B, należący do grupy epotilonów. Jest on substratem enzymu CYP3A4. (pl)
dbo:alternativeName	Ixempra (en)
dbo:casNumber	219989-84-1
dbo:chEMBL	1201752
dbo:drugbank	DB04845
dbo:fdaUniiCode	K27005NP0A
dbo:kegg	D04645
dbo:medlinePlus	a608042
dbo:pubchem	6445540
dbo:thumbnail	wiki-commons:Special:FilePath/Ixabepilone.svg?width=300
dbo:wikiPageExternalLink	http://www.ixempra.com/ https://web.archive.org/web/20160129134623/http:/packageinserts.bms.com/pi/pi_ixempra.pdf
dbo:wikiPageID	11979825 (xsd:integer)
dbo:wikiPageLength	8005 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1092789517 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Capecitabine dbr:Epothilone dbr:Non-Hodgkin's_lymphoma dbr:Breast_cancer dbr:Anthracycline dbr:Intravenous_therapy dbr:Structural_analog dbc:Epoxides dbc:Lactams dbr:Liver dbr:Bristol-Myers_Squibb dbc:Thiazoles dbr:European_Medicines_Agency dbr:Food_and_Drug_Administration dbc:Mitotic_inhibitors dbr:International_Nonproprietary_Name dbr:Taxane dbr:Taxol dbc:Bristol_Myers_Squibb dbr:Chemotherapy dbr:Kidney dbr:Sorangium_cellulosum dbr:CYP3A4 dbr:Metabolic_stability dbr:Metastasis dbr:Medicinal_chemistry dbr:Microtubule dbr:Pharmacokinetics dbr:Semi-synthetic
dbp:atcPrefix	L01 (en)
dbp:atcSuffix	DC04 (en)
dbp:bioavailability	N/A (en)
dbp:c	27 (xsd:integer)
dbp:casNumber	219989 (xsd:integer)
dbp:chembl	1201752 (xsd:integer)
dbp:chemspiderid	20145579 (xsd:integer)
dbp:drugbank	DB04845 (en)
dbp:eliminationHalfLife	187200.0
dbp:excretion	Fecal and renal (en)
dbp:h	42 (xsd:integer)
dbp:iupacName	-610 (xsd:integer) 99 (xsd:integer) heptadecane-8,12-dione (en)
dbp:iupharLigand	6824 (xsd:integer)
dbp:kegg	D04645 (en)
dbp:legalUs	Rx-only (en)
dbp:licenceUs	Ixabepilone (en)
dbp:medlineplus	a608042 (en)
dbp:metabolism	Extensive, hepatic, CYP3A4-mediated (en)
dbp:n	2 (xsd:integer)
dbp:o	5 (xsd:integer)
dbp:pregnancyUs	D (en)
dbp:proteinBound	67 (xsd:integer)
dbp:pubchem	6445540 (xsd:integer)
dbp:routesOfAdministration	dbr:Intravenous_therapy
dbp:s	1 (xsd:integer)
dbp:smiles	Cc3nccs3 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	FABUFPQFXZVHFB-PVYNADRNSA-N (en)
dbp:synonyms	Azaepothilone B (en)
dbp:tradename	Ixempra (en)
dbp:unii	K27005NP0A (en)
dbp:verifiedfields	changed (en)
dbp:verifiedrevid	477495917 (xsd:integer)
dbp:width	250 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Chemotherapeutic_agents dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Drugs.com
dcterms:subject	dbc:Epoxides dbc:Lactams dbc:Thiazoles dbc:Mitotic_inhibitors dbc:Bristol_Myers_Squibb
gold:hypernym	dbr:Analog
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAmides yago:Abstraction100002137 yago:Alcohol114708720 yago:Amide114724264 yago:Chemical114806838 yago:Compound114818238 yago:Diol114835980 yago:Fluid114939900 yago:Ketone114926294 yago:Liquid114940386 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 yago:WikicatKetones dbo:Drug yago:Substance100019613 yago:WikicatDiols umbel-rc:DrugProduct
rdfs:comment	يُعد عقار إكسابيبيلون (المعروف أيضًا باسم azaepothilone B، والذي يحمل الاسم الرمزي BMS-247550 )دواءًا صيدلانيًا طورته شركة بريستول-مايرز سكويب كدواء علاجي كيميائي للسرطان. (ar) Ixabepilone (INN; also known as azaepothilone B, codenamed BMS-247550) is a pharmaceutical drug developed by Bristol-Myers Squibb as a chemotherapeutic medication for cancer. (en) Iksabepilon – organiczny związek chemiczny, półsyntetyczny analog epotilonu B, należący do grupy epotilonów. Jest on substratem enzymu CYP3A4. (pl)
rdfs:label	إكسابيبيلون (ar) Ixabepilone (en) Iksabepilon (pl)
owl:sameAs	freebase:Ixabepilone yago-res:Ixabepilone wikidata:Ixabepilone dbpedia-ar:Ixabepilone dbpedia-fa:Ixabepilone dbpedia-pl:Ixabepilone dbpedia-ro:Ixabepilone dbpedia-sh:Ixabepilone dbpedia-sr:Ixabepilone dbpedia-vi:Ixabepilone https://global.dbpedia.org/id/E9C2
prov:wasDerivedFrom	wikipedia-en:Ixabepilone?oldid=1092789517&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Ixabepilone.svg
foaf:isPrimaryTopicOf	wikipedia-en:Ixabepilone
is dbo:wikiPageRedirects of	dbr:C27H42N2O5S dbr:Ixempra dbr:ATC_code_L01DC04 dbr:ATCvet_code_QL01DC04 dbr:BMS-247550
is dbo:wikiPageWikiLink of	dbr:Epothilone dbr:List_of_antineoplastic_agents dbr:Index_of_oncology_articles dbr:Chemotherapy-induced_peripheral_neuropathy dbr:Endometrial_cancer dbr:Myxobacteria dbr:Linezolid dbr:Post-chemotherapy_cognitive_impairment dbr:Bristol_Myers_Squibb dbr:C27H42N2O5S dbr:Diverted_total_synthesis dbr:Ixempra dbr:Causes_of_cancer_pain dbr:Kolliphor_EL dbr:ATC_code_L01DC04 dbr:ATCvet_code_QL01DC04 dbr:ATC_code_L01 dbr:Sorangium_cellulosum dbr:Porphyria dbr:Microtubule dbr:List_of_drugs:_Iq–Iv dbr:BMS-247550
is foaf:primaryTopic of	wikipedia-en:Ixabepilone