Joshua M. Sharfstein (born 1969) is a physician and the current Vice Dean for Public Health Practice and Community Engagement at the Johns Hopkins Bloomberg School of Public Health. He was Secretary of the Maryland Department of Health from 2011 to 2014, and was principal deputy commissioner of the U.S Food and Drug Administration until he stepped down from his post on January 5, 2011. He is the former health commissioner of Baltimore, Maryland.