An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Methyllycaconitine (MLA) is a diterpenoid alkaloid found in many species of Delphinium (larkspurs). In common with many other diterpenoid alkaloids, it is toxic to animals, although the acute toxicity varies with species. Early research was focused on identifying, and characterizing the properties of methyllycaconitine as one of the principal toxins in larkspurs responsible for livestock poisoning in the mountain rangelands of North America. Methyllycaconitine has been explored as a possible therapeutic agent for the treatment of spastic paralyses in man, and it has been shown to have insecticidal properties. Most recently, it has become an important molecular probe for studying the pharmacology of the nicotinic acetylcholine receptor.

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dbo:abstract
  • Methyllycaconitine (MLA) is a diterpenoid alkaloid found in many species of Delphinium (larkspurs). In common with many other diterpenoid alkaloids, it is toxic to animals, although the acute toxicity varies with species. Early research was focused on identifying, and characterizing the properties of methyllycaconitine as one of the principal toxins in larkspurs responsible for livestock poisoning in the mountain rangelands of North America. Methyllycaconitine has been explored as a possible therapeutic agent for the treatment of spastic paralyses in man, and it has been shown to have insecticidal properties. Most recently, it has become an important molecular probe for studying the pharmacology of the nicotinic acetylcholine receptor. (en)
  • La méthyllycaconitine (MLA) est un très toxique que l'on trouve dans les plantes du genre Delphinium. C'est un composé de type N-(méthylsuccinyl)-anthranoyllycoctonine. (fr)
dbo:casNumber
  • 21019-30-7
dbo:chEMBL
  • 510275
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  • 8H7EX9Z9QE
dbo:pubchem
  • 5311278
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  • 21019 (xsd:integer)
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  • CCN1CC2COCC7=CC=CC=C7N8CCCC (en)
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  • Methyllycaconitine (MLA) is a diterpenoid alkaloid found in many species of Delphinium (larkspurs). In common with many other diterpenoid alkaloids, it is toxic to animals, although the acute toxicity varies with species. Early research was focused on identifying, and characterizing the properties of methyllycaconitine as one of the principal toxins in larkspurs responsible for livestock poisoning in the mountain rangelands of North America. Methyllycaconitine has been explored as a possible therapeutic agent for the treatment of spastic paralyses in man, and it has been shown to have insecticidal properties. Most recently, it has become an important molecular probe for studying the pharmacology of the nicotinic acetylcholine receptor. (en)
  • La méthyllycaconitine (MLA) est un très toxique que l'on trouve dans les plantes du genre Delphinium. C'est un composé de type N-(méthylsuccinyl)-anthranoyllycoctonine. (fr)
rdfs:label
  • Méthyllycaconitine (fr)
  • Methyllycaconitine (en)
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