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Michael Eisenbach (Hebrew: מיכאל אייזנבך), Ph.D., is an Israeli biochemist who specializes in the navigation mechanisms of bacterial and sperm cells. He is a professor emeritus at the Weizmann Institute of Science, Department of Biomolecular Sciences, Rehovot, Israel. He discovered that sperm cells (spermatozoa) of mammals are actively guided to the egg. This opened the research field of mammalian sperm navigation (also termed sperm guidance). He demonstrated that the active navigation entails chemotaxis and thermotaxis. He made seminal contributions to the understanding of these two processes at the molecular, physiological and behavioural levels, as well as contributing to our understanding of the molecular mechanism of bacterial chemotaxis.