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- Le rapacuronium est un curare non dépolarisant de la famille des stéroïdes commercialisé au début des années 2000 aux États-Unis sous forme de bromure de rapacuronium (Raplon). Il s'est révélé pourvoyeur de bronchospasmes dont certains ont été mortels : le médicament a été retiré du marché en mars 2001. (fr)
- Rapacuronium bromide (brand name Raplon) is a rapidly acting, non-depolarizing aminosteroid neuromuscular blocker formerly used in modern anaesthesia, to aid and enable endotracheal intubation, which is often necessary to assist in the controlled ventilation of unconscious patients during surgery and sometimes in intensive care. As a non-depolarizing agent it did not cause initial stimulation of muscles before weakening them. Due to risk of fatal bronchospasm it was withdrawn from the United States market by Organon on March 27, 2001, less than 2 years after its FDA approval in 1999. (en)
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- 4289 (xsd:nonNegativeInteger)
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- Rapacuronium bromide (en)
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- CYP system not involved (en)
- Hydrolyzed to active metabolites (en)
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- LVQTUXZKLGXYIU-GWSNJHLMSA-M (en)
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- ([-3-acetyloxy-10,13-dimethyl-2--16--2 ,3 ,4 ,5 ,6 ,7 ,8 ,9 ,11 ,12 ,14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate) (en)
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- Le rapacuronium est un curare non dépolarisant de la famille des stéroïdes commercialisé au début des années 2000 aux États-Unis sous forme de bromure de rapacuronium (Raplon). Il s'est révélé pourvoyeur de bronchospasmes dont certains ont été mortels : le médicament a été retiré du marché en mars 2001. (fr)
- Rapacuronium bromide (brand name Raplon) is a rapidly acting, non-depolarizing aminosteroid neuromuscular blocker formerly used in modern anaesthesia, to aid and enable endotracheal intubation, which is often necessary to assist in the controlled ventilation of unconscious patients during surgery and sometimes in intensive care. As a non-depolarizing agent it did not cause initial stimulation of muscles before weakening them. Due to risk of fatal bronchospasm it was withdrawn from the United States market by Organon on March 27, 2001, less than 2 years after its FDA approval in 1999. (en)
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- Rapacuronium (fr)
- Rapacuronium bromide (en)
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