About: Ribosome display

An Entity of Type: topical concept, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Ribosome display is a technique used to perform in vitro protein evolution to create proteins that can bind to a desired ligand. The process results in translated proteins that are associated with their mRNA progenitor which is used, as a complex, to bind to an immobilized ligand in a selection step. The mRNA-protein hybrids that bind well are then reverse transcribed to cDNA and their sequence amplified via PCR. The result is a nucleotide sequence that can be used to create tightly binding proteins.

Property Value
dbo:abstract
  • Das Ribosomen-Display ist eine biochemische Methode zum Nachweis von Protein-Protein-Interaktionen oder zur Identifikation der DNA-Sequenz eines Proteinliganden. Es ist eine Variante des molekularen Displays. (de)
  • Ribosome display is a technique used to perform in vitro protein evolution to create proteins that can bind to a desired ligand. The process results in translated proteins that are associated with their mRNA progenitor which is used, as a complex, to bind to an immobilized ligand in a selection step. The mRNA-protein hybrids that bind well are then reverse transcribed to cDNA and their sequence amplified via PCR. The result is a nucleotide sequence that can be used to create tightly binding proteins. (en)
dbo:wikiPageID
  • 1952693 (xsd:integer)
dbo:wikiPageLength
  • 7391 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1123484061 (xsd:integer)
dbo:wikiPageWikiLink
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Das Ribosomen-Display ist eine biochemische Methode zum Nachweis von Protein-Protein-Interaktionen oder zur Identifikation der DNA-Sequenz eines Proteinliganden. Es ist eine Variante des molekularen Displays. (de)
  • Ribosome display is a technique used to perform in vitro protein evolution to create proteins that can bind to a desired ligand. The process results in translated proteins that are associated with their mRNA progenitor which is used, as a complex, to bind to an immobilized ligand in a selection step. The mRNA-protein hybrids that bind well are then reverse transcribed to cDNA and their sequence amplified via PCR. The result is a nucleotide sequence that can be used to create tightly binding proteins. (en)
rdfs:label
  • Ribosomen-Display (de)
  • Ribosome display (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageDisambiguates of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License
  NODES