About: Scoulerine

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Scoulerine, also known as discretamine and aequaline, is a benzylisoquinoline alkaloid (BIA) that is derived directly from (S)-reticuline through the action of berberine bridge enzyme. It is a precursor of other BIAs, notably berberine, noscapine, (S)-tetrahydropalmatine, and (S)-stylopine, as well as the alkaloids protopine, and sanguinarine. It is found in many plants, including opium poppy, , and certain plants in the genus Erythrina.

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  • Scoulerine, also known as discretamine and aequaline, is a benzylisoquinoline alkaloid (BIA) that is derived directly from (S)-reticuline through the action of berberine bridge enzyme. It is a precursor of other BIAs, notably berberine, noscapine, (S)-tetrahydropalmatine, and (S)-stylopine, as well as the alkaloids protopine, and sanguinarine. It is found in many plants, including opium poppy, , and certain plants in the genus Erythrina. Studies show that scoulerine is an antagonist in vitro at the α2-adrenoceptor, α1D-adrenoceptor and 5-HT receptor. It has also been found to be a GABAA receptor agonist in vitro. (en)
dbo:alternativeName
  • (S)-Scoulerin; Discretamine; Aequaline (en)
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  • (13aS)-3,10-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline-2,9-diol (en)
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  • 6552196 (xsd:integer)
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  • 5138 (xsd:nonNegativeInteger)
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  • 1023750338 (xsd:integer)
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  • Scoulerine-S.png (en)
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  • Scoulerine (en)
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  • Scoulerine (en)
dbp:othernames
  • -Scoulerin; Discretamine; Aequaline (en)
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  • -310 (xsd:integer)
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  • changed (en)
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  • 464388032 (xsd:integer)
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  • Scoulerine, also known as discretamine and aequaline, is a benzylisoquinoline alkaloid (BIA) that is derived directly from (S)-reticuline through the action of berberine bridge enzyme. It is a precursor of other BIAs, notably berberine, noscapine, (S)-tetrahydropalmatine, and (S)-stylopine, as well as the alkaloids protopine, and sanguinarine. It is found in many plants, including opium poppy, , and certain plants in the genus Erythrina. (en)
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  • Scoulerine (en)
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foaf:name
  • Scoulerine (en)
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