Sini Jose (Malayalam: സിനി ജോസ്) (born 25 May 1987) is an Indian sprint athlete from Ernakulam district, Kerala who specializes in 400 metres. Sini won the Gold Medal at the 2010 Commonwealth Games and 2010 Asian Games in 4x400 m relay event with Manjeet Kaur, A. C. Ashwini, and Mandeep Kaur.