Perspectives [2]

• Genetic basis of kidney cancer: Role of genomics for the development of disease-based therapeutics

  W. Marston Linehan
• Translating genomic information into clinical medicine: Lung cancer as a paradigm

  Mia A. Levy ... William Pao

Research [11]

• The transcriptional landscape and mutational profile of lung adenocarcinoma

  Jeong-Sun Seo ... Young Tae Kim
• Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

  Han Liang ... Gordon B. Mills
• A functional methylome map of ulcerative colitis

  Robert Häsler ... Philip Rosenstiel
• Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans

  Huriya Beyan ... Vardhman K. Rakyan
• Nurture trumps nature in a longitudinal survey of salivary bacterial communities in twins from early adolescence to early adulthood

  Simone S. Stahringer ... Kenneth S. Krauter
• Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner

  Jason Gertz ... Richard M. Myers
• Cohesin regulates tissue-specific expression by stabilizing highly occupied cis -regulatory modules

  Andre J. Faure ... Paul Flicek
• Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains

  Kevin Van Bortle ... Victor G. Corces
• Nature and function of insulator protein binding sites in the Drosophila genome

  Yuri B. Schwartz ... Vincenzo Pirrotta
• The BEAF-32 insulator coordinates genome organization and function during the evolution of Drosophila species

  Jingping Yang ... Victor G. Corces
• Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting

  Claudia Fritsch ... Mario Brosch

Methods [8]

• Observation of dually decoded regions of the human genome using ribosome profiling data

  Audrey M. Michel ... Pavel V. Baranov
• Ultrafast genome-wide scan for SNP–SNP interactions in common complex disease

  Snehit Prabhu, Itsik Pe'er
• Paired-end sequencing of Fosmid libraries by Illumina

  Louise J.S. Williams ... Andreas Gnirke
• nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing

  Andrew McPherson ... S. Cenk Sahinalp
• Spark: A navigational paradigm for genomic data exploration

  Cydney B. Nielsen ... Steven J.M. Jones
• Finished bacterial genomes from shotgun sequence data

  Filipe J. Ribeiro ... David B. Jaffe
• Systematic elucidation and in vivo validation of sequences enriched in hindbrain transcriptional control

  Grzegorz M. Burzynski ... Andrew S. McCallion
• Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes

  David U. Gorkin ... Andrew S. McCallion

Resource [1]

• A miRNA-regulatory network explains how dysregulated miRNAs perturb oncogenic processes across diverse cancers

  Christopher L. Plaisier ... Nitin S. Baliga