Abstract
Over the years, external beam radiotherapy (EBRT) has been used in the treatment management of many malignancies, including head and neck squamous cell carcinomas (HNSCC). Hypoxia is a common feature in HNSCC. Hypoxic segments in HNSCC have proven to be more resistant to radiotherapy. The ability to identify hypoxia using SPECT and PET tracers has been investigated since the late 1970s. Nitroimidazole-based compounds labelled with positron emitters have been developed to more specifically image hypoxia. This article reviews the current data from research publications on18F–FMISO, 18F-FAZA, 18F-EF5 and 64Cu-ATSM.
Keywords: Head and neck cancers, hypoxia, PET/CT tracers, radiotherapy planning.
Graphical Abstract
Call for Papers in Thematic Issues
Federated Learning for Secure Medical Imaging Data Sharing in Healthcare Networks.
Decentralised machine learning model training is known as federated learning. Instead of sharing the original data, federated learning shares model changes, such as gradient information, which inherently safeguards the data kept on each device. But since model updates are dependent on the original data, they may expose private information. For ...read more
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