doi: 10.1248/cpb.53.1423.
Biotransformation of citrus aromatics nootkatone and valencene by microorganisms
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- PMID: 16272725
- DOI: 10.1248/cpb.53.1423
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Biotransformation of citrus aromatics nootkatone and valencene by microorganisms
Chem Pharm Bull (Tokyo).
2005 Nov.
Free article
Abstract
Biotransformations of the sesquiterpene ketone nootkatone from the crude drug Alpiniae Fructus and grapefruit oil, and the sesquiterpene hydrocarbon valencene from Valencia orange oil were carried out with microorganisms such as Aspergillus niger, Botryosphaeria dothidea, and Fusarium culmorum to afford structurally interesting metabolites. Their stereostructures were established by a combination of high-resolution NMR spectral and X-ray crystallographic analysis and chemical reaction. Metabolic pathways of compounds and by A. niger are proposed.
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