Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking
- PMID: 17336279
- DOI: 10.1016/j.cca.2007.01.028
Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking
Abstract
Thiobarbituric acid reactive substances (TBARS) and malondialdehyde (MDA) have been used as biomarkers of lipid oxidation for more than thirty years. The validity of these biomarkers has been rightfully criticized for a lack of specificity and problems with post sampling formation. Numerous assays have been published for their analysis giving rise to reference intervals for healthy non-smoking humans varying more than to orders of magnitude. In spite of these problems, these biomarkers remain among the most commonly reported indices of oxidative damage and the present review focuses on the problems associated with MDA/TBARS analysis, their potential as biomarkers of oxidative stress and the effect of smoking on MDA status.
Similar articles
-
[Determination of selected biomarkers can be used in monitoring oxidative stress in the course of chronic failure].Pol Merkur Lekarski. 2005 Mar;18(105):358-61. Pol Merkur Lekarski. 2005. PMID: 15997653 Review. Polish.
-
[Evaluation of lipid peroxidation by measuring thiobarbituric acid reactive substances].Ann Biol Clin (Paris). 1998 May-Jun;56(3):305-19. Ann Biol Clin (Paris). 1998. PMID: 9754263 Review. French.
-
Cigarette smoke induced oxidative insult in local population of Pokhara.Kathmandu Univ Med J (KUMJ). 2007 Oct-Dec;5(4):511-7. Kathmandu Univ Med J (KUMJ). 2007. PMID: 18604085
-
Biomarkers for oxidative stress status of DNA, lipids, and proteins in vitro and in vivo cancer research.Toxicology. 2007 Jan 5;229(1-2):1-10. doi: 10.1016/j.tox.2006.10.013. Epub 2006 Oct 29. Toxicology. 2007. Retraction in: Toxicology. 2007 Nov 20;241(1-2):98. doi: 10.1016/j.tox.2007.08.093 PMID: 17118505 Retracted. Review.
-
The levels of lycopene, alpha-tocopherol and a marker of oxidative stress in healthy northeast Thai elderly.Asia Pac J Clin Nutr. 2007;16 Suppl 1:27-30. Asia Pac J Clin Nutr. 2007. PMID: 17392072
Cited by
-
Biomarkers of oxidative stress following continuous positive airway pressure withdrawal: data from two randomised trials.Eur Respir J. 2015 Oct;46(4):1065-71. doi: 10.1183/09031936.00023215. Epub 2015 May 28. Eur Respir J. 2015. PMID: 26022961 Free PMC article. Clinical Trial.
-
Smoking and red blood cell phospholipid membrane fatty acids.Prostaglandins Leukot Essent Fatty Acids. 2016 Sep;112:24-31. doi: 10.1016/j.plefa.2016.08.004. Epub 2016 Aug 16. Prostaglandins Leukot Essent Fatty Acids. 2016. PMID: 27637337 Free PMC article.
-
Urinary Malondialdehyde (MDA) Concentrations in the General Population-A Systematic Literature Review and Meta-Analysis.Toxics. 2022 Mar 29;10(4):160. doi: 10.3390/toxics10040160. Toxics. 2022. PMID: 35448421 Free PMC article. Review.
-
Effect of exogenous progesterone treatment on ovarian steroid hormones and oxidant and antioxidant biomarkers during peak and low breeding seasons in dromedary she-camel.Vet World. 2019;12(4):542-550. doi: 10.14202/vetworld.2019.542-550. Epub 2019 Apr 17. Vet World. 2019. PMID: 31190709 Free PMC article.
-
NOX1, 2, 4, 5: counting out oxidative stress.Br J Pharmacol. 2011 Oct;164(3):866-83. doi: 10.1111/j.1476-5381.2011.01249.x. Br J Pharmacol. 2011. PMID: 21323893 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
