This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Email citation

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Review

. 2010 Apr;7(4):786-804.

doi: 10.1002/cbdv.201000005.

Peptide nucleic acids (PNA) in chemical biology and drug discovery

Peter E Nielsen¹

Affiliations

Affiliation

¹ Department of Cellular and Molecular Medicine, Faculty of Health Sciences, The Panum Institute, University of Copenhagen, Blegdamsvej 3c, DK-2200, Copenhagen. ptrn@sund.ku.dk

PMID: 20397216
DOI: 10.1002/cbdv.201000005

Review

Peptide nucleic acids (PNA) in chemical biology and drug discovery

Peter E Nielsen. Chem Biodivers. 2010 Apr.

. 2010 Apr;7(4):786-804.

doi: 10.1002/cbdv.201000005.

Author

Peter E Nielsen¹

Affiliation

¹ Department of Cellular and Molecular Medicine, Faculty of Health Sciences, The Panum Institute, University of Copenhagen, Blegdamsvej 3c, DK-2200, Copenhagen. ptrn@sund.ku.dk

PMID: 20397216
DOI: 10.1002/cbdv.201000005

No abstract available

PubMed Disclaimer

Similar articles

Versatility of peptide nucleic acids (PNAs): role in chemical biology, drug discovery, and origins of life.
Sharma C, Awasthi SK. Sharma C, et al. Chem Biol Drug Des. 2017 Jan;89(1):16-37. doi: 10.1111/cbdd.12833. Epub 2016 Sep 14. Chem Biol Drug Des. 2017. PMID: 27490868 Review.
Metal complex derivatives of peptide nucleic acids (PNA).
Krämer R, Mokhir A. Krämer R, et al. Met Ions Life Sci. 2012;10:319-40. doi: 10.1007/978-94-007-2172-2_12. Met Ions Life Sci. 2012. PMID: 22210345 Review.
Expanding the repertoire of pyrrolidyl PNA analogues for DNA/RNA hybridization selectivity: aminoethylpyrrolidinone PNA (aepone-PNA).
Sharma NK, Ganesh KN. Sharma NK, et al. Chem Commun (Camb). 2003 Oct 7;(19):2484-5. doi: 10.1039/b307362a. Chem Commun (Camb). 2003. PMID: 14587743
_targeted gene repair facilitated by peptide nucleic acids (PNA).
Nielsen PE. Nielsen PE. Chembiochem. 2010 Oct 18;11(15):2073-6. doi: 10.1002/cbic.201000346. Chembiochem. 2010. PMID: 20872391 Review. No abstract available.
PNA Technology.
Nielsen PE. Nielsen PE. Mol Biotechnol. 2004 Mar;26(3):233-48. doi: 10.1385/MB:26:3:233. Mol Biotechnol. 2004. PMID: 15004293 Review.

See all similar articles

Cited by

Pioneering role of RNA in the early evolution of life.
Muñoz-Velasco I, Cruz-González A, Hernández-Morales R, Campillo-Balderas JA, Cottom-Salas W, Jácome R, Vázquez-Salazar A. Muñoz-Velasco I, et al. Genet Mol Biol. 2024 Sep 2;47Suppl 1(Suppl 1):e20240028. doi: 10.1590/1678-4685-GMB-2024-0028. eCollection 2024. Genet Mol Biol. 2024. PMID: 39437147 Free PMC article.
A Convenient Oligonucleotide Conjugation via Tandem Staudinger Reaction and Amide Bond Formation at the Internucleotidic Phosphate Position.
Klabenkova KV, Zhdanova PV, Burakova EA, Bizyaev SN, Fokina AA, Stetsenko DA. Klabenkova KV, et al. Int J Mol Sci. 2024 Feb 7;25(4):2007. doi: 10.3390/ijms25042007. Int J Mol Sci. 2024. PMID: 38396686 Free PMC article.
Promising strategies employing nucleic acids as antimicrobial drugs.
Moreira L, Guimarães NM, Santos RS, Loureiro JA, Pereira MC, Azevedo NF. Moreira L, et al. Mol Ther Nucleic Acids. 2024 Jan 18;35(1):102122. doi: 10.1016/j.omtn.2024.102122. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2024. PMID: 38333674 Free PMC article. Review.
De Novo Potent Peptide Nucleic Acid Antisense Oligomer Inhibitors _targeting SARS-CoV-2 RNA-Dependent RNA Polymerase via Structure-Guided Drug Design.
Shehzadi K, Yu M, Liang J. Shehzadi K, et al. Int J Mol Sci. 2023 Dec 14;24(24):17473. doi: 10.3390/ijms242417473. Int J Mol Sci. 2023. PMID: 38139312 Free PMC article.
Peptide Nucleic Acids Containing Cationic/Amino-Alkyl Modified Bases Promote Enhanced Hybridization Kinetics and Thermodynamics with Single-Strand DNA.
Podlaski F, Cornwell S, Wong K, McKittrick B, Kim JH, Jung D, Jeon Y, Jung KB, Tolias P, Windsor WT. Podlaski F, et al. ACS Omega. 2023 Sep 6;8(37):33426-33436. doi: 10.1021/acsomega.3c03184. eCollection 2023 Sep 19. ACS Omega. 2023. PMID: 37744819 Free PMC article.

See all "Cited by" articles

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

LinkOut - more resources

Full Text Sources
- Wiley
Other Literature Sources
- The Lens - Patent Citations Database

NODES