Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 May 17:9:88.
doi: 10.1186/1749-8090-9-88.

Long-term outcomes after video-assisted thoracic surgery (VATS) lobectomy versus lobectomy via open thoracotomy for clinical stage IA non-small cell lung cancer

Mitsunori Higuchi  1 , Hiroshi Yaginuma, Atsushi Yonechi, Ryuzo Kanno, Akio Ohishi, Hiroyuki Suzuki, Mitsukazu Gotoh
Affiliations

Long-term outcomes after video-assisted thoracic surgery (VATS) lobectomy versus lobectomy via open thoracotomy for clinical stage IA non-small cell lung cancer

Mitsunori Higuchi et al. J Cardiothorac Surg. .

Abstract

Background: Video-assisted thoracic surgery (VATS) lobectomy is a standard treatment for lung cancer. This study retrospectively compared long-term outcomes after VATS lobectomy versus lobectomy via open thoracotomy for clinical stage IA non-small cell lung cancer (NSCLC).

Methods: From July 2002 to June 2012, 160 patients were diagnosed with clinical stage IA NSCLC and underwent lobectomy. Of these, 114 underwent VATS lobectomy and 46 underwent lobectomy via open thoracotomy.

Results: The 5-year disease-free survival (DFS) rate was 88.0% in the VATS group and 77.1% in the thoracotomy group for clinical stage IA NSCLC (p = 0.1504), and 91.5% in the VATS group and 93.8% in the thoracotomy group for pathological stage IA NSCLC (p = 0.2662). The 5-year overall survival (OS) rate was 94.1% in the VATS group and 81.8% in the thoracotomy group for clinical stage IA NSCLC (p = 0.0268), and 94.8% in the VATS group and 96.2% in the thoracotomy group for pathological stage IA NSCLC (p = 0.5545). The rate of accurate preoperative staging was 71.9% in the VATS group and 56.5% in the thoracotomy group (p = 0.2611). Inconsistencies between the clinical and pathological stages were mainly related to tumor size, nodal status, and pleural invasion. Local recurrence occurred for one lesion in the VATS group and six lesions (five patients) in the thoracotomy group (p = 0.0495).

Conclusions: The DFS and OS were not inferior after VATS compared with thoracotomy. Local control was significantly better after VATS than after thoracotomy. Preoperative staging lacked sufficient accuracy.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Five-year disease-free survival (DFS) (a) and overall survival (OS) (b) for patients with clinical stage IA non-small-cell lung cancer (NSCLC). The 5-year DFS rate was 88.0% in the VATS group and 77.1% in the thoracotomy group (p = 0.1504), and the 5-year OS rate was 94.1% in the VATS group and 81.8% in the thoracotomy group (p = 0.0268).
Figure 2
Figure 2
Five-year DFS (a) and OS (b) for patients with pathological stage IA NSCLC. The 5-year DFS rate was 91.5% in the VATS group and 93.8% in the thoracotomy group (p = 0.2662), and the 5-year OS rate was 94.8% in the VATS group and 96.2% in the thoracotomy group (p = 0.5545).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Surveillance, Epidemiology, and End Results (SEER) Cancer Statistics Review, 1975–2010. http://seer.cancer.gov/csr/1975_2010. Accessed 14 June 2013.
    1. McKenna RJ Jr. Lobectomy by video-assisted thoracic surgery with mediastinal node sampling for lung cancer. J Thorac Cardiovasc Surg. 1994;9:879–882. - PubMed
    1. Flores RM, Park BJ, Dycoco J, Aronova A, Hirth Y, Rizk NP, Bains M, Downey RJ, Rusch VW. Lobectomy by video-assisted thoracic surgery (VATS) versus thoracotomy for lung cancer. J Thorac Cardiovasc Surg. 2009;9:11–18. doi: 10.1016/j.jtcvs.2009.03.030. - DOI - PubMed
    1. McKenna RJ Jr, Houck W, Fuller CB. Video-assisted thoracic surgery lobectomy: experience with 1,100 cases. Ann Thorac Surg. 2006;9:421–425. doi: 10.1016/j.athoracsur.2005.07.078. - DOI - PubMed
    1. Onaitis MW, Petersen RP, Balderson SS, Toloza E, Burfeind WR, Harpole DH Jr, D’Amico TA. Thoracoscopic lobectomy is a safe and versatile procedure: experience with 500 consecutive patients. Ann Surg. 2006;9:420–425. - PMC - PubMed

MeSH terms

  NODES
chat 2
twitter 2