Human monkeypox (hMPXV) re-emergence: Host immunity status and current vaccines landscape

doi:10.1002/jmv.28251

Review

. 2023 Jan;95(1):e28251.

doi: 10.1002/jmv.28251. Epub 2022 Nov 2.

Human monkeypox (hMPXV) re-emergence: Host immunity status and current vaccines landscape

Maryam Shafaati^{1

2}, Milad Zandi³

Affiliations

¹ Department of Microbiology, Faculty of Science, Jahrom Branch, Islamic Azad University, Jahrom, Iran.
² Occupational Sleep Research, Baharloo Hospital, Tehran University of Medical Science, Tehran, Iran.
³ Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

PMID: 36271768
DOI: 10.1002/jmv.28251

Review

Human monkeypox (hMPXV) re-emergence: Host immunity status and current vaccines landscape

Maryam Shafaati et al. J Med Virol. 2023 Jan.

. 2023 Jan;95(1):e28251.

doi: 10.1002/jmv.28251. Epub 2022 Nov 2.

Authors

Maryam Shafaati^{1

2}, Milad Zandi³

Affiliations

¹ Department of Microbiology, Faculty of Science, Jahrom Branch, Islamic Azad University, Jahrom, Iran.
² Occupational Sleep Research, Baharloo Hospital, Tehran University of Medical Science, Tehran, Iran.
³ Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

PMID: 36271768
DOI: 10.1002/jmv.28251

Abstract

Monkeypox virus is a member of the Orthopoxvirus genus and the Poxviridae family. Orthopoxviruses are among the most intricate animal viruses. The pathogenicity of human monkeypox infection has been emphasized in response to its recent emergence in non-endemic countries and the threat of bioterrorism. It is always necessary to take appropriate precautions in exposure to emerging or re-emerging infections. Here, we focus on the current state of the human monkeypox infection outbreak, research & development of immune responses, and clinical interventions to prevent and treat the human monkeypox virus and other human poxviruses.

Keywords: monkeypox virus; neutralizing antibodies; pathogenicity; vaccine.

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References

REFERENCES

1. WHO. Multi-country monkeypox outbreak in non-endemic countries 21 May 2022. 2022. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON385
1. Shafaati M, Zandi M. Monkeypox virus neurological manifestations in comparison to other orthopoxviruses. Travel Med Infect Dis. 2022;49:102414.
1. Shafaati M, Zandi M, Choudhary OP. Monkeypox virus crosstalk with HIV; where do we stand now? Int J Surg. 2022;105:106897.
1. Olivero J, Fa JE, Real R, et al. Recent loss of closed forests is associated with Ebola virus disease outbreaks. Sci Rep. 2017;7(1):14291.
1. Seang S, Burrel S, Todesco E, et al. Evidence of human-to-dog transmission of monkeypox virus. Lancet. 2022;400:658-659.

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[1] WHO. Multi-country monkeypox outbreak in non-endemic countries 21 May 2022. 2022. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON385

[2] WHO. Multi-country monkeypox outbreak in non-endemic countries 21 May 2022. 2022. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON385

[3] Shafaati M, Zandi M. Monkeypox virus neurological manifestations in comparison to other orthopoxviruses. Travel Med Infect Dis. 2022;49:102414.

[4] Shafaati M, Zandi M. Monkeypox virus neurological manifestations in comparison to other orthopoxviruses. Travel Med Infect Dis. 2022;49:102414.

[5] Shafaati M, Zandi M, Choudhary OP. Monkeypox virus crosstalk with HIV; where do we stand now? Int J Surg. 2022;105:106897.

[6] Shafaati M, Zandi M, Choudhary OP. Monkeypox virus crosstalk with HIV; where do we stand now? Int J Surg. 2022;105:106897.

[7] Olivero J, Fa JE, Real R, et al. Recent loss of closed forests is associated with Ebola virus disease outbreaks. Sci Rep. 2017;7(1):14291.

[8] Olivero J, Fa JE, Real R, et al. Recent loss of closed forests is associated with Ebola virus disease outbreaks. Sci Rep. 2017;7(1):14291.

[9] Seang S, Burrel S, Todesco E, et al. Evidence of human-to-dog transmission of monkeypox virus. Lancet. 2022;400:658-659.

[10] Seang S, Burrel S, Todesco E, et al. Evidence of human-to-dog transmission of monkeypox virus. Lancet. 2022;400:658-659.

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Human monkeypox (hMPXV) re-emergence: Host immunity status and current vaccines landscape

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Human monkeypox (hMPXV) re-emergence: Host immunity status and current vaccines landscape

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