{"id":"https://openalex.org/W2073939393","doi":"https://doi.org/10.1186/s12859-015-0562-8","title":"IPO: a tool for automated optimization of XCMS parameters","display_name":"IPO: a tool for automated optimization of XCMS parameters","publication_year":2015,"publication_date":"2015-04-15","ids":{"openalex":"https://openalex.org/W2073939393","doi":"https://doi.org/10.1186/s12859-015-0562-8","mag":"2073939393","pmid":"https://pubmed.ncbi.nlm.nih.gov/25888443","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4404568"},"language":"en","primary_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-015-0562-8","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-015-0562-8","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310320256"],"host_organization_lineage_names":["Springer Nature","BioMed Central"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},"type":"article","type_crossref":"journal-article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-015-0562-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034928211","display_name":"Gunnar Libiseller","orcid":null},"institutions":[{"id":"https://openalex.org/I13402291","display_name":"Joanneum Research","ror":"https://ror.org/049bdss47","country_code":"AT","type":"facility","lineage":["https://openalex.org/I13402291"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Gunnar Libiseller","raw_affiliation_strings":["Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, Austria","institution_ids":["https://openalex.org/I13402291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086332463","display_name":"Michaela Dvorzak","orcid":null},"institutions":[{"id":"https://openalex.org/I13402291","display_name":"Joanneum Research","ror":"https://ror.org/049bdss47","country_code":"AT","type":"facility","lineage":["https://openalex.org/I13402291"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Michaela Dvorzak","raw_affiliation_strings":["Joanneum Research Forschungsgesellschaft m.b.H., POLICIES, Institute for Economic and Innovation Research, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Joanneum Research Forschungsgesellschaft m.b.H., POLICIES, Institute for Economic and Innovation Research, Graz, Austria","institution_ids":["https://openalex.org/I13402291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053123958","display_name":"Ulrike Kleb","orcid":null},"institutions":[{"id":"https://openalex.org/I13402291","display_name":"Joanneum Research","ror":"https://ror.org/049bdss47","country_code":"AT","type":"facility","lineage":["https://openalex.org/I13402291"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Ulrike Kleb","raw_affiliation_strings":["Joanneum Research Forschungsgesellschaft m.b.H., POLICIES, Institute for Economic and Innovation Research, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Joanneum Research Forschungsgesellschaft m.b.H., POLICIES, Institute for Economic and Innovation Research, Graz, Austria","institution_ids":["https://openalex.org/I13402291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088430222","display_name":"Edgar Gander","orcid":null},"institutions":[{"id":"https://openalex.org/I13402291","display_name":"Joanneum Research","ror":"https://ror.org/049bdss47","country_code":"AT","type":"facility","lineage":["https://openalex.org/I13402291"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Edgar Gander","raw_affiliation_strings":["Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, Austria","institution_ids":["https://openalex.org/I13402291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018303103","display_name":"Tobias Eisenberg","orcid":"https://orcid.org/0000-0003-3559-1130"},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]},{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Tobias Eisenberg","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, 8010, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, 8010, Graz, Austria","institution_ids":["https://openalex.org/I15766117","https://openalex.org/I4210108044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078054009","display_name":"Frank Madeo","orcid":"https://orcid.org/0000-0002-5070-1329"},"institutions":[{"id":"https://openalex.org/I4210108044","display_name":"Nawi Graz","ror":"https://ror.org/01mm16571","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210108044"]},{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Frank Madeo","raw_affiliation_strings":["Institute of Molecular Biosciences, NAWI Graz, University of Graz, 8010, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Institute of Molecular Biosciences, NAWI Graz, University of Graz, 8010, Graz, Austria","institution_ids":["https://openalex.org/I4210108044","https://openalex.org/I15766117"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038786156","display_name":"Steffen Neumann","orcid":"https://orcid.org/0000-0002-7899-7192"},"institutions":[{"id":"https://openalex.org/I4210110463","display_name":"Leibniz Institute of Plant Biochemistry","ror":"https://ror.org/01mzk5576","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210110463"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffen Neumann","raw_affiliation_strings":["Department of Stress- and Developmental Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Stress- and Developmental Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany","institution_ids":["https://openalex.org/I4210110463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043805180","display_name":"Gert Trausinger","orcid":null},"institutions":[{"id":"https://openalex.org/I13402291","display_name":"Joanneum Research","ror":"https://ror.org/049bdss47","country_code":"AT","type":"facility","lineage":["https://openalex.org/I13402291"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Gert Trausinger","raw_affiliation_strings":["Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, Austria","institution_ids":["https://openalex.org/I13402291"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002136055","display_name":"Frank Sinner","orcid":"https://orcid.org/0000-0002-9292-4512"},"institutions":[{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Frank Sinner","raw_affiliation_strings":["Department of Internal Medicine, Medical University of Graz, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023877066","display_name":"Thomas R. Pieber","orcid":"https://orcid.org/0000-0003-3554-0405"},"institutions":[{"id":"https://openalex.org/I202276237","display_name":"Medical University of Graz","ror":"https://ror.org/02n0bts35","country_code":"AT","type":"education","lineage":["https://openalex.org/I202276237"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Thomas Pieber","raw_affiliation_strings":["Department of Internal Medicine, Medical University of Graz, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Medical University of Graz, Graz, Austria","institution_ids":["https://openalex.org/I202276237"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022216027","display_name":"Christoph Magnes","orcid":"https://orcid.org/0000-0002-5153-7444"},"institutions":[{"id":"https://openalex.org/I13402291","display_name":"Joanneum Research","ror":"https://ror.org/049bdss47","country_code":"AT","type":"facility","lineage":["https://openalex.org/I13402291"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Christoph Magnes","raw_affiliation_strings":["Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, Austria"],"affiliations":[{"raw_affiliation_string":"Joanneum Research Forschungsgesellschaft m.b.H., HEALTH, Institute for Biomedicine and Health Sciences, Graz, Austria","institution_ids":["https://openalex.org/I13402291"]}]}],"institution_assertions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1690,"currency":"GBP","value_usd":2072,"provenance":"doaj"},"apc_paid":{"value":2076,"currency":"EUR","value_usd":2238,"provenance":"openapc"},"fwci":8.975,"has_fulltext":true,"fulltext_origin":"pdf","cited_by_count":299,"citation_normalized_percentile":{"value":0.999985,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"16","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"primary_topic":{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9798,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.9738,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/data-set","display_name":"Data set","score":0.4917803},{"id":"https://openalex.org/keywords/isotopologue","display_name":"Isotopologue","score":0.4586681},{"id":"https://openalex.org/keywords/design-of-experiments","display_name":"Design of experiments","score":0.44323045},{"id":"https://openalex.org/keywords/sample","display_name":"Sample (material)","score":0.429349}],"concepts":[{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.61353666},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5377026},{"id":"https://openalex.org/C58489278","wikidata":"https://www.wikidata.org/wiki/Q1172284","display_name":"Data set","level":2,"score":0.4917803},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4826439},{"id":"https://openalex.org/C129848803","wikidata":"https://www.wikidata.org/wiki/Q2564360","display_name":"Sample size determination","level":2,"score":0.47163603},{"id":"https://openalex.org/C13934619","wikidata":"https://www.wikidata.org/wiki/Q2198720","display_name":"Isotopologue","level":3,"score":0.4586681},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.45480272},{"id":"https://openalex.org/C34559072","wikidata":"https://www.wikidata.org/wiki/Q2334061","display_name":"Design of experiments","level":2,"score":0.44323045},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.429349},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.3348547},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2446819},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.23907253},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.13774592},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.10891032},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002853","descriptor_name":"Chromatography, Liquid","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002250","descriptor_name":"Carbon Radioisotopes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011381","descriptor_name":"Programming Languages","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":"","qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":"","qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-015-0562-8","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-015-0562-8","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310320256"],"host_organization_lineage_names":["Springer Nature","BioMed Central"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404568","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true},{"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25888443","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":["National Institutes of Health"],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false}],"best_oa_location":{"is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12859-015-0562-8","pdf_url":"https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/s12859-015-0562-8","source":{"id":"https://openalex.org/S19032547","display_name":"BMC Bioinformatics","issn_l":"1471-2105","issn":["1471-2105"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310319965","https://openalex.org/P4310320256"],"host_organization_lineage_names":["Springer Nature","BioMed Central"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true},"sustainable_development_goals":[],"grants":[],"datasets":[],"versions":[],"referenced_works_count":22,"referenced_works":["https://openalex.org/W143096088","https://openalex.org/W1607252236","https://openalex.org/W1964010911","https://openalex.org/W1965258535","https://openalex.org/W1989299822","https://openalex.org/W1995543670","https://openalex.org/W2012660994","https://openalex.org/W2022067114","https://openalex.org/W2038866778","https://openalex.org/W2038872823","https://openalex.org/W2043451976","https://openalex.org/W2053300710","https://openalex.org/W2080046774","https://openalex.org/W2082706597","https://openalex.org/W2087597413","https://openalex.org/W2098667036","https://openalex.org/W2130319566","https://openalex.org/W2143481724","https://openalex.org/W2146095608","https://openalex.org/W2158447287","https://openalex.org/W2168590651","https://openalex.org/W2322461740"],"related_works":["https://openalex.org/W4388813866","https://openalex.org/W4236933217","https://openalex.org/W3047225376","https://openalex.org/W2999104021","https://openalex.org/W2850804095","https://openalex.org/W2800688113","https://openalex.org/W2162280767","https://openalex.org/W2057598446","https://openalex.org/W1570799877","https://openalex.org/W1481656249"],"abstract_inverted_index":{"Un_targeted":[0],"metabolomics":[1],"generates":[2],"a":[3,70],"huge":[4],"amount":[5],"of":[6,23,31,79],"data.":[7,20],"Software":[8],"packages":[9,26],"for":[10,73],"automated":[11],"data":[12,32],"processing":[13,33],"are":[14,42],"crucial":[15],"to":[16,52],"successfully":[17],"process":[18],"these":[19],"A":[21],"variety":[22],"such":[24],"software":[25,71],"exist,":[27],"but":[28,69],"the":[29],"outcome":[30],"strongly":[34],"depends":[35],"on":[36],"algorithm":[37],"parameter":[38,47,56,62,74],"settings.":[39],"If":[40],"they":[41],"not":[43],"carefully":[44],"chosen,":[45],"suboptimal":[46],"settings":[48,57],"can":[49],"easily":[50],"lead":[51],"biased":[53],"results.":[54],"Therefore,":[55],"also":[58],"require":[59],"optimization.":[60],"Several":[61],"optimization":[63,75],"approaches":[64],"have":[65],"already":[66],"been":[67],"proposed,":[68],"package":[72],"which":[76],"is":[77,88],"free":[78],"intricate":[80],"experimental":[81],"labeling":[82],"steps,":[83],"fast":[84],"and":[85],"widely":[86],"applicable":[87],"still":[89],"missing.":[90]},"cited_by_api_url":"https://api.openalex.org/works?filter=cites:W2073939393","counts_by_year":[{"year":2024,"cited_by_count":25},{"year":2023,"cited_by_count":36},{"year":2022,"cited_by_count":34},{"year":2021,"cited_by_count":46},{"year":2020,"cited_by_count":51},{"year":2019,"cited_by_count":36},{"year":2018,"cited_by_count":33},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":21},{"year":2015,"cited_by_count":2}],"updated_date":"2024-12-31T11:07:07.376337","created_date":"2016-06-24"}
  NODES
innovation 4
INTERN 4