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Table of contents

January 2023 - Volume 2 - 1

Research

9 November 2023open access icon
Diet in the management of type 2 diabetes: umbrella review of systematic reviews with meta-analyses of randomised controlled trials
Edyta Szczerba, Janett Barbaresko, Tim Schiemann, Anna Stahl-Pehe, Lukas Schwingshackl, Sabrina Schlesinger
28 November 2023open access icon
Transgender identity in young people and adults recorded in UK primary care electronic patient records: retrospective, dynamic, cohort study
Douglas Gordon John McKechnie, Elizabeth O'Nions, Julia Bailey, Lorna Hobbs, Frank Gillespie, Irene Petersen
27 October 2023open access icon
Use of covid-19 convalescent plasma to treat patients admitted to hospital for covid-19 with or without underlying immunodeficiency: open label, randomised clinical trial
Karine Lacombe, Thomas Hueso, Raphael Porcher, Arsene Mekinian, Thibault Chiarabini, Sophie Georgin-Lavialle, Florence Ader, Julien Saison, Guillaume Martin-Blondel, Nathalie De Castro, Fabrice Bonnet, Charles Cazanave, Anne Francois, Pascal Morel, Olivier Hermine, Valerie Pourcher, Marc Michel, Xavier Lescure, Nora Soussi, Phillipe Brun, Fanny Pommeret, Pierre Sellier, Stella Rousset, Lionel Piroth, Jean-Marie Michot, Gabriel Baron, Xavier de Lamballerie, Xavier Mariette, Pierre-Louis Tharaux, Matthieu Resche-Rigon, Philippe Ravaud, Tabassome Simon, Pierre Tiberghien
17 October 2023open access icon
Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog
Aroon D Hingorani, Jasmine Gratton, Chris Finan, A Floriaan Schmidt, Riyaz Patel, Reecha Sofat, Valerie Kuan, Claudia Langenberg, Harry Hemingway, Joan K Morris, Nicholas J Wald
7 November 2023open access icon
Effect of national guidance on survival for babies born at 22 weeks’ gestation in England and Wales: population based cohort study
Lucy K Smith, Emily van Blankenstein, Grenville Fox, Sarah E Seaton, Mario Martínez-Jiménez, Stavros Petrou, Cheryl Battersby, , , Elizabeth S Draper, Alan C Fenton, Ian Gallimore, Jennifer J Kurinczuk, Bradley N Manktelow, Ruth J Matthews, , Matthew Babirecki, Rebecca Kettle, Anand Kamalanathan, Clare Cane, Kavi Aucharaz, Rathod Poorva, Maninder Bal, LM Wong, Anita Mittal, Penny Broggio, Pinki Surana, Matt Nash, Sam Wallis, Ahmed Hassan, Karin Schwarz, Shu-Ling Chuang, Penelope Young, Ramona Onita, Mani Kandasamy, Stephen Brearey, Dr Morris, Dr Siramhatia, Yee Aung, Bharath Gowda, Mehdi Garbash, Alex Allwood, Pauline Adiotomre, Nigel Brooke, Claire Hollinsworh, Toria Klutse, Sonia Spathis, Sathish Krishnan, Samar Sen, Alaa Ghoneem, Jennifer Holman, Daniel Dogar, Girish Gowda, Karen Turnock, Sobia Balal, Cath Seagrave, Tristan Bate, Hilary Dixon, Narendra Aladangady, Hassan Gaili, Matthew James, M Lal, Oluseun Tayo, Abraham Isaac, Carolina Zorro, Dhaval Dave, Jonathan Filkin, Savi Sivashankar, Hannah Shore, Jo Behrsin, Michael Grosdenier, Ruchika Gupta, Ather Ahmed, Nim Subhedar, Jennifer Birch, Surendran Chandrasekaran, Ashok Karupaiah, Ghada Ramadan, I Misra, Chris Knight, Richard Heaver, Mohammad Alam, Prakash Thiagarajan, Tiziana Fragapane Muthukumar, Bivan Saha, Cheentan Singh, Nick Barnes, Sangeeta Tiwary, Richard Nicholl, Dush Batra, Victoria Nesbitt, Amit Gupta, Katharine McDevitt, Ruchika Gupta, David Gibson, Peter Mcewan, Sanath Reddy, Mark Johnson, Aesha Mohammedi, Patricia Cowley, Rashmi Gandhi, Charlotte Groves, Lidia Tyszcuzk, Shilpa Ramesh, Salamatu Jalloh, Julia Croft, Bushra Abdul-Malik, Dominic Muogbo, Ambalika Das, Khalid Mannan, Rajiv Chaudhary, Soma Sengupta, Christos Zipitis, Kemy Naidoo, Archana Mishra, Chris Warren, Nigel Ruggins, Chrissie Oliver, Lucinda Winckworth, Joanne Fedee, Anitha Vayalakkad, Richa Gupta, Lee Abbott, Jo MacLeod, Aesha Mohammedi, Rebecca Winterson, Naveen Athiraman, Anjali Pektar, Jim Baird, Adedayo Owoeye, Umapathee Majuran, Richard Lindley, Vineet Gupta, Faith Emery, Donovan Duffy, Salim Yasin, Hannah Shore, Akinsola Ogundiya, Lidia Tyszcuzk, Arin Mukherjee, Pamela Cairns, Vennila Ponnusamy, Victoria Sharp, Carrie Heal, Sanjay Salgia, Imran Ahmed, Helen Purves, Porus Bastani, Eleanor Bond, Divyen Shah, Esther Morris, Se-Yeon Park, Giles Kendall, Puneet Nath, Igor Fierens, Mehdi Garbash, Hari Kumar, Peter Curtis, Delyth Webb, Dr Bird, Sankara Narayanan, Yee Mon Aung, Elizabeth Eyre, Tayyaba Aamir, Angela Yannoulias, Caroline Sullivan, Ros Garr, Wynne Leith, Shaveta Mulla, Anna Gregory, Edward Yates, Abijeet Godhamgaonkar, Megan Eaton, Sundeep Sandhu, Saulius Satas, Clare Irving, Andrew Eccleston, S Kinmond, Shelagh Parkinson, Dominic O'Reilly, Dr Bhushan, Andrew Powls, P Van Der Heide, Hilary Conetta, J Coutts, AM Heuchan, Helen Rhodes Ben Stenson, Laura Stewart, Caroline Delahunty, Arun Ramachandran, Abby Parish, Anitha James, Ambrose Onibere, Artur Abelian, Shakir Saeed, Nitin Goel, David Deekollu, Prem Pitchaikani, Stan Craig, Sanjeev Bali, Nita Saxena, Alison Verner, Damien Armstrong
6 October 2023open access icon
Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM
Rohan Khera, Lovedeep Singh Dhingra, Arya Aminorroaya, Kelly Li, Jin J Zhou, Faaizah Arshad, Clair Blacketer, Mary G Bowring, Fan Bu, Michael Cook, David A Dorr, Talita Duarte-Salles, Scott L DuVall, Thomas Falconer, Tina E French, Elizabeth E Hanchrow, Scott Horban, Wallis CY Lau, Jing Li, Yuntian Liu, Yuan Lu, Kenneth KC Man, Michael E Matheny, Nestoras Mathioudakis, Michael F McLemore, Evan Minty, Daniel R Morales, Paul Nagy, Akihiko Nishimura, Anna Ostropolets, Andrea Pistillo, Jose D Posada, Nicole Pratt, Carlen Reyes, Joseph S Ross, Sarah Seager, Nigam Shah, Katherine Simon, Eric YF Wan, Jianxiao Yang, Can Yin, Seng Chan You, Martijn J Schuemie, Patrick B Ryan, George Hripcsak, Harlan Krumholz, Marc A Suchard
13 September 2023open access icon
Sensitivity, specificity, and diagnostic accuracy of WHO 2013 criteria for diagnosis of gestational diabetes mellitus in low risk early pregnancies: international, prospective, multicentre cohort study
Evelyn A Huhn, Christian S Göbl, Thorsten Fischer, Monya Todesco Bernasconi, Martina Kreft, Mirjam Kunze, Deborah R Vogt, Eva Dölzlmüller, Heidi Jaksch-Bogensperger, Sandra Heldstab, Wolfgang Eppel, Peter Husslein, Nicole Ochsenbein Kölble, Anne Richter, Elke Bäz, Bettina Winzeler, Irene Hoesli
11 September 2023open access icon
Preconception contraceptive use and miscarriage: prospective cohort study
Jennifer J Yland, Amelia K Wesselink, Sonia Hernandez-Diaz, Krista Huybrechts, Elizabeth E Hatch, Tanran R Wang, David Savitz, Wendy Kuohung, Kenneth J Rothman, Lauren A Wise
30 August 2023open access icon
Association between perinatal mortality and morbidity and customised and non-customised birthweight centiles in Denmark, Finland, Norway, Wales, and England: comparative, population based, record linkage study
Fanny Kilpi, Hayley E Jones, Maria Christine Magnus, Gillian Santorelli, Lise Kristine Højsgaard Schmidt, Stine Kjaer Urhoj, Scott M Nelson, Derek Tuffnell, Robert French, Per Minor Magnus, Anne-Marie Nybo Andersen, Pekka Martikainen, Kate Tilling, Deborah A Lawlor
21 September 2023open access icon
Quality of reporting of adverse events in clinical trials of covid-19 drugs: systematic review
Karima Madi, Clara Flumian, Pascale Olivier, Agnès Sommet, François Montastruc
9 August 2023open access icon
Comparative effectiveness of second line glucose lowering drug treatments using real world data: emulation of a _target trial
Yihong Deng, Eric C Polley, Joshua D Wallach, Jeph Herrin, Joseph S Ross, Rozalina G McCoy
14 July 2023open access icon
Familial aggregation of multimorbidity in Sweden: national explorative family study
Bengt Zöller, MirNabi Pirouzifard, Björn Holmquist, Jan Sundquist, Anders Halling, Kristina Sundquist
11 July 2023open access icon
Pregnancy, fetal, and neonatal outcomes after a first booster dose of covid-19 vaccine during pregnancy in Ontario, Canada: population based, retrospective cohort study
Deshayne B Fell, Sheryll Dimanlig-Cruz, Eszter Török, Siri E Håberg, Annette K Regan, Jay S Kaufman, Robert W Platt, Christopher A Gravel, Liam Bruce, Prakesh S Shah, Kumanan Wilson, Ann E Sprague, Gillian D Alton, Tavleen Dhinsa, Darine El-Chaâr, Sarah A Buchan, Jeffrey C Kwong, Sarah E Wilson, Sandra I Dunn, Shannon E MacDonald, Jon Barrett, Nannette Okun, Mark C Walker
10 July 2023open access icon
Vaccine effectiveness for prevention of covid-19 related hospital admission during pregnancy in England during the alpha and delta variant dominant periods of the SARS-CoV-2 pandemic: population based cohort study
Matthew L Bosworth, Ryan Schofield, Daniel Ayoubkhani, Loes Charlton, Vahé Nafilyan, Kamlesh Khunti, Francesco Zaccardi, Clare Gillies, Ashley Akbari, Marian Knight, Rachael Wood, Pia Hardelid, Luisa Zuccolo, Camille Harrison
25 June 2023open access icon
Association between adiposity after diagnosis of prostate cancer and mortality: systematic review and meta-analysis
Margarita Cariolou, Georgios Markozannes, Nerea Becerra-Tomás, Rita Vieira, Katia Balducci, Dagfinn Aune, David C Muller, Doris S M Chan, Konstantinos K Tsilidis
6 June 2023open access icon
Risk of admission to hospital with arterial or venous thromboembolism among patients diagnosed in the ambulatory setting with covid-19 compared with influenza: retrospective cohort study
Vincent Lo Re, Sarah K Dutcher, John G Connolly, Silvia Perez-Vilar, Dena M Carbonari, Terese A DeFor, Djeneba Audrey Djibo, Laura B Harrington, Laura Hou, Sean Hennessy, Rebecca A Hubbard, Maria E Kempner, Jennifer L Kuntz, Cheryl N McMahill-Walraven, Jolene Mosley, Pamala A Pawloski, Andrew B Petrone, Allyson M Pishko, Meighan Rogers Driscoll, Claudia A Steiner, Yunping Zhou, Noelle M Cocoros
24 May 2023open access icon
Association between SARS-CoV-2 infection and newly diagnosed hypertension during pregnancy: prospective, population based cohort study
Anne K. Örtqvist, Maria C. Magnus, Elisabeth Dahlqvist, Jonas Söderling, Kari Johansson, Anna Sandström, Siri E. Håberg, Olof Stephansson
19 May 2023open access icon
Changes in medication safety indicators in England throughout the covid-19 pandemic using OpenSAFELY: population based, retrospective cohort study of 57 million patients using federated analytics
Louis Fisher, Lisa EM Hopcroft, Sarah Rodgers, James Barrett, Kerry Oliver, Anthony J Avery, Dai Evans, Helen Curtis, Richard Croker, Orla Macdonald, Jessica Morley, Amir Mehrkar, Sebastian Bacon, Simon Davy, Iain Dillingham, David Evans, George Hickman, Peter Inglesby, Caroline E Morton, Becky Smith, Tom Ward, William Hulme, Amelia Green, Jon Massey, Alex J Walker, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Shaun O’Hanlon, Alex Eavis, Richard Jarvis, Dima Avramov, Paul Griffiths, Aaron Fowles, Nasreen Parkes, Ben Goldacre, Brian MacKenna
16 May 2023open access icon
Changes in the care of acute cerebrovascular and cardiovascular conditions during the first year of the covid-19 pandemic in 746 hospitals in the USA: retrospective analysis
Raul G Nogueira, Katherine Etter, Thanh N Nguyen, Shelly Ikeme, Charlene Wong, Michael Frankel, Diogo C Haussen, Carlos Del Rio, Michael McDaniel, Rajesh Sachdeva, Chandan M Devireddy, Alhamza R Al-Bayati, Mahmoud H Mohammaden, Mohamed F Doheim, Agostinho C Pinheiro, Bernardo Liberato, Dinesh V Jillella, Nirav R Bhatt, Rahul Khanna
12 April 2023open access icon
Impact of work schedules of senior resident physicians on patient and resident physician safety: nationwide, prospective cohort study
Laura K Barger, Matthew D Weaver, Jason P Sullivan, Salim Qadri, Christopher P Landrigan, Charles A Czeisler
3 April 2023open access icon
Inequalities in SARS-CoV-2 case rates by ethnicity, religion, measures of socioeconomic position, English proficiency, and self-reported disability: cohort study of 39 million people in England during the alpha and delta waves
Tim Larsen, Matthew L Bosworth, Daniel Ayoubkhani, Ryan Schofield, Raghib Ali, Kamlesh Khunti, Ann Sarah Walker, Myer Glickman, Camille Harrison, Vahé Nafilyan
24 March 2023open access icon
Vascular thrombosis after single dose Ad26.COV2.S vaccine in healthcare workers in South Africa: open label, single arm, phase 3B study (Sisonke study)
Barry Frank Jacobson, Elise Schapkaitz, Azwi Takalani, Pradeep Rowji, Vernon Johan Louw, Jessica Opie, Linda-Gail Bekker, Nigel Garrett, Ameena Goga, Tarylee Reddy, Nonhlanhla Yende-Zuma, Ian Sanne, Ishen Seocharan, Jonny Peter, Michelle Robinson, Shirley Collie, Amber Khan, Simbarashe Takuva, Glenda Gray
14 March 2023open access icon
Reproductive outcomes in women and men conceived by assisted reproductive technologies in Norway: prospective registry based study
Ellen Øen Carlsen, Allen J Wilcox, Maria Christine Magnus, Hans Ivar Hanevik, Siri Eldevik Håberg
28 February 2023open access icon
Effect of covid-19 vaccination on long covid: systematic review
Oyungerel Byambasuren, Paulina Stehlik, Justin Clark, Kylie Alcorn, Paul Glasziou
14 February 2023open access icon
The interplay between inflammatory cytokines and cardiometabolic disease: bi-directional mendelian randomisation study
Ville Karhunen, Dipender Gill, Jian Huang, Emmanouil Bouras, Rainer Malik, Mark J Ponsford, Ari Ahola-Olli, Areti Papadopoulou, Saranya Palaniswamy, Sylvain Sebert, Matthias Wielscher, Juha Auvinen, Juha Veijola, Karl-Heinz Herzig, Markku Timonen, Sirkka Keinänen-Kiukaanniemi, Martin Dichgans, Marko Salmi, Sirpa Jalkanen, Terho Lehtimäki, Veikko Salomaa, Olli Raitakari, Simon A Jones, G Kees Hovingh, Konstantinos K Tsilidis, Marjo-Riitta Järvelin, Abbas Dehghan
13 February 2023open access icon
Sex differences in cardiovascular complications and mortality in hospital patients with covid-19: registry based observational study
Carinna Hockham, Marijke Linschoten, Folkert W Asselbergs, Chahinda Ghossein, Mark Woodward, Sanne A E Peters, , AK Al-Ali, FA Al-Muhanna, NYY Al-Windy, YA Almubarak, AN Alnafie, M Alshahrani, AM Alshehri, RL Anthonio, FW Asselbergs, A Aujayeb, JM ten Berg, AJM van Boxem, G Captur, M Caputo, N Charlotte, P Dark, J De Sutter, CE Delsing, HGR Dorman, JT Drost, ME Emans, JB Ferreira, L Gabriel, WH van Gilst, BE Groenemeijer, HE Haerkens-Arends, P van der Harst, B Hedayat, DJ van der Heijden, E Hellou, RS Hermanides, JF Hermans-van Ast, MWJ van Hessen, SRB Heymans, ICC van der Horst, SH van Ierssel, LS Jewbali, MT Kearney, HAM van Kesteren, Kietselaer BLJH, AMH Koning, PY Kopylov, AFM Kuijper, JM Kwakkel-vanErp, van der Linden MMJM, M Linschoten, GCM Linssen, Macias Ruiz R, FJH Magdelijns, Martens FMAC, GP McCann, P van der Meer, MFL Meijs, P Messiaen, PS Monraats, L Montagna, A Moriarty, A Mosterd, PR Nierop, CEE van Ofwegen-Hanekamp, YM Pinto, H Poorhosseini, S Prasad, J Redón, AC Reidinga, MIA Ribeiro, DP Ripley, R Salah, E Saneei, M Saxena, J Schaap, Schellings DAAM, A Schut, A Shafiee, AC Shore, HJ Siebelink, M van Smeden, PC Smits, R Pisters, E Tessitore, RG Tieleman, P Timmermans, RA Tio, FVY Tjong, CA den Uil, EM Van Craenenbroeck, van Veen HPAA, T Veneman, DO Verschure, JK de Vries, RMA van de Wal, DJ van de Watering, ICD Westendorp, PHM Westendorp, C Weytjens, E Wierda, B Williams, P Woudstra, KW Wu, R Zaal, AG Zaman, PM van derZee
1 February 2023open access icon
Clinical outcomes of myocarditis after SARS-CoV-2 mRNA vaccination in four Nordic countries: population based cohort study
Anders Husby, Hanne Løvdal Gulseth, Petteri Hovi, Jørgen Vinsløv Hansen, Nicklas Pihlström, Nina Gunnes, Tommi Härkänen, Jesper Dahl, Øystein Karlstad, Tiina Heliö, Lars Køber, Rickard Ljung, Anders Hviid
30 January 2023open access icon
Association between coeliac disease and cardiovascular disease: prospective analysis of UK Biobank data
Megan Conroy, Naomi Allen, Ben Lacey, Elizabeth Soilleux, Thomas Littlejohns
13 January 2023open access icon
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY
Amelia C A Green, Helen J Curtis, Rose Higgins, Linda Nab, Viyaasan Mahalingasivam, Rebecca M Smith, Amir Mehrkar, Peter Inglesby, Henry Drysdale, Nicholas J DeVito, Richard Croker, Christopher T Rentsch, Krishnan Bhaskaran, John Tazare, Bang Zheng, Colm D Andrews, Sebastian C J Bacon, Simon Davy, Iain Dillingham, David Evans, Louis Fisher, George Hickman, Lisa E M Hopcroft, William J Hulme, Jon Massey, Orla MacDonald, Jessica Morley, Caroline E Morton, Robin Y Park, Alex J Walker, Tom Ward, Milan Wiedemann, Christopher Bates, Jonathan Cockburn, John Parry, Frank Hester, Sam Harper, Ian J Douglas, Stephen J W Evans, Ben Goldacre, Laurie A Tomlinson, Brian MacKenna
5 January 2023open access icon
Metrics, baseline scores, and a tool to improve sponsor performance on clinical trial diversity: retrospective cross sectional study
Tanvee Varma, Michelle Mello, Joseph S Ross, Cary Gross, Jennifer Miller

Research methods and reporting

4 May 2023open access icon
Quantifying the impact of unmeasured confounding in observational studies with the E value
Tobias Gaster, Christine Marie Eggertsen, Henrik Støvring, Vera Ehrenstein, Irene Petersen
16 May 2023open access icon
Defining representativeness of study samples in medical and population health research
Jacqueline E Rudolph, Yongqi Zhong, Priya Duggal, Shruti H Mehta, Bryan Lau
19 September 2023open access icon
Transparent reporting of adaptive clinical trials using concurrently randomised cohorts
Ian C Marschner, Mark Jones, James A Totterdell, Robert K Mahar, Thomas L Snelling, Steven Y C Tong, , Bhupendra Basnet, Asha Bowen, Joshua Davis, Justin Denholm, Naomi Hammond, Vivekanand Jha, Grace McPhee, Zoe McQuilten, Susan Morpeth, Matthew O’Sullivan, David Paterson, David Price, Megan Rees, Jason Roberts, Nanette Trask, Balasubramanian Venkatesh, Sanjeev Chunilal, Jennifer Curnow, Joseph John, James McFadyen, Robert Medcalf, Eileen Merriman, Huyen Tran, Todd Cooper, Julie Marsh, Tim Spelman, James McGree

Reviews

4 September 2023open access icon
Advances in the management of type 2 diabetes in adults
Rodolfo J Galindo, Jennifer M Trujillo, Cecilia C Low Wang, Rozalina G McCoy
9 August 2023open access icon
Advances in mechanical thrombectomy for acute ischaemic stroke
Oishik Raha, Charles Hall, Abid Malik, Lucio D'Anna, Kyriakos Lobotesis, Joseph Kwan, Soma Banerjee
27 June 2023open access icon
Stillbirth: prevention and supportive bereavement care
Bethany Atkins, Lindsay Kindinger, Muhammad Pradhiki Mahindra, Zoe Moatti, Dimitrios Siassakos
25 June 2023open access icon
Advances in the pathogenesis and personalised treatment of paediatric asthma
Elizabeth Scotney, Louise Fleming, Sejal Saglani, Samatha Sonnappa, Andrew Bush
20 July 2023open access icon
Post-viral olfactory loss and parosmia
Zhen Yu Liu, Luigi Angelo Vaira, Paolo Boscolo-Rizzo, Abigail Walker, Claire Hopkins
24 March 2023open access icon
Pathophysiology and new advances in pulmonary hypertension
Simon Bousseau, Rafael Sobrano Fais, Sue Gu, Andrea Frump, Tim Lahm
5 January 2023open access icon
Role of precision medicine in obstructive sleep apnoea
Yu Liu, Ali Abdul Ghafoor, Mohammadreza Hajipour, Najib Ayas

Specialist reviews

22 November 2023open access icon
T cell immune memory after covid-19 and vaccination
Lulu Wang, Alex Nicols, Lance Turtle, Alex Richter, Christopher JA Duncan, Susanna J Dunachie, Paul Klenerman, Rebecca P Payne

Opinion

Education

7 August 2023open access icon
New and emerging treatments for myasthenia gravis
Mckenzye DeHart-McCoyle, Shital Patel, Xinli Du

Methods primers

20 January 2023open access icon
Non-linear predictor outcome associations
Frederick K Ho, Tim J Cole
  NODES
Association 6
COMMUNITY 1
INTERN 1