ZG16

Zimogeni zrnasti protein 16, znan i kao ZG16, je ljudski gen.

ZG16
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 3APA, 3VY6, 3VY7, 3VZE, 3VZF, 3VZG
Identifikatori
Aliasi	ZG16
Vanjski ID-jevi	OMIM: 617311 MGI: 1916286 HomoloGene: 12296 GeneCards: ZG16
Lokacija gena (čovjek) Hrom. Hromosom 16 (čovjek) Bend 16p11.2 Početak 29,778,256 bp Kraj 29,782,973 bp
Lokacija gena (miš) Hrom. Hromosom 7 (miš) Bend 7|7 F3 Početak 126,649,328 bp Kraj 126,686,500 bp
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine • carbohydrate binding Ćelijska komponenta • Golgi lumen • cytoplasmic vesicle lumen • extracellular region • GO:0005578 Vanćelijski matriks • Golđijev aparat • GO:0016023 citoplazmatska vezikula • zymogen granule membrane • collagen-containing extracellular matrix • Vanćelijsko Biološki proces • protein transport Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	653808	69036
Ensembl	ENSG00000174992	ENSMUSG00000049350
UniProt	O60844	Q8K0C5
RefSeq (mRNK)	NM_152338	NM_026918
RefSeq (bjelančevina)	NP_689551	NP_081194
Lokacija (UCSC)	Chr 16: 29.78 – 29.78 Mb	Chr 7: 126.65 – 126.69 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 167 aminokiselina, a molekulska težina 18.147 Da..

10		20		30		40		50
MLTVALLALL		CASASGNAIQ		ARSSSYSGEY		GGGGGKRFSH		SGNQLDGPIT
ALRVRVNTYY		IVGLQVRYGK		VWSDYVGGRN		GDLEEIFLHP		GESVIQVSGK
YKWYLKKLLF		VTDKGRYLSF		GKDSGTSFNA		VPLHPNTVLR		FISGRSGSLI
DAIGLHWDVY		PSSCSRC

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

Dopunska literatura

• Zhou YB, Cao JB, Yang HM, et al. (2007). "hZG16, a novel human secreted protein expressed in liver, was down-regulated in hepatocellular carcinoma". Biochem. Biophys. Res. Commun. 355 (3): 679–86. doi:10.1016/j.bbrc.2007.02.020. PMID 17307141.
• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
• Cronshagen U, Voland P, Kern HF (1995). "cDNA cloning and characterization of a novel 16 kDa protein located in zymogen granules of rat pancreas and goblet cells of the gut". Eur. J. Cell Biol. 65 (2): 366–77. PMID 7720729.