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English: Figure 1. Source of “inflammaging”. Among the main causes of inflammaging, the accumulation of cell senescence, pro-coagulation factors, cell debris such as circulating mitochondrial DNA (cmtDNA), gut dysbiosis, and immune senescence is known to be the main causes of inflammaging. Inflammaging can also be influenced by many other factors, including age itself, reactive oxygen species (ROS), and those not directly related to inflammation, such as microRNAs (miRs) and agalactosylated N-glycans.
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Source https://www.frontiersin.org/articles/10.3389/fcvm.2018.00012/full
Author Fumihiro Sanada, Yoshiaki Taniyama, Jun Muratsu, Rei Otsu, Hideo Shimizu, Hiromi Rakugi and Ryuichi Morishita

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