File:ΔFosB.svg
Original file (SVG file, nominally 935 × 965 pixels, file size: 238 KB)
Captions
Summary
editDescriptionΔFosB.svg |
English: The finished, wikilink annotated version is currently located at en:Template:Psychostimulant addiction; a more detailed image caption is located there as well. For external (off-wiki) use, a screenshot of the annotated version is located at File:Annotated ΔFosB.svg screenshot.png. This image shows the signal transduction that occurs in nucleus accumbens D1-type medium spiny neurons that gives rise to psychostimulant addiction. This signaling cascade occurs during chronic high-dose use of certain dopaminergic stimulants (e.g., phenethylamine, methamphetamine, amphetamine, etc.). Cocaine induces a slightly different signaling cascade than the one shown here.
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Date | |
Source | Own work |
Author | Joseph Mickel (Seppi333) |
Other versions | File:Annotated ΔFosB.svg screenshot.png - labeled version |
Associated ΔFosB expression graph InfoField | File:ΔFosB accumulation.svg – shows how ΔFosB is induced following acute and repeated drug exposure and how it accumulates in neurons with repeated exposure to addictive drugs. |
Presynaptic diagram InfoField | File:TAAR1 Dopamine.svg – illustrates the other side of the synaptic cleft for amphetamine and endogenous phenethylamine. |
Licensing
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Annotations InfoField | This image is annotated: View the annotations at Commons |
Top: ΔFosB
Bottom: JunD
This complex is the activator protein 1 transcription factor.
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 19:41, 9 November 2016 | 935 × 965 (238 KB) | Seppi333 (talk | contribs) | added 1 gene product box for AC in the cAMP pathway | |
23:29, 21 July 2014 | 935 × 965 (238 KB) | Seppi333 (talk | contribs) | g protein color | ||
23:15, 21 July 2014 | 935 × 965 (238 KB) | Seppi333 (talk | contribs) | changes to membrane structures | ||
00:53, 21 July 2014 | 935 × 965 (223 KB) | Seppi333 (talk | contribs) | last recoloring | ||
00:02, 21 July 2014 | 935 × 965 (228 KB) | Seppi333 (talk | contribs) | +1 upload | ||
23:46, 20 July 2014 | 935 × 965 (228 KB) | Seppi333 (talk | contribs) | Reverted to version as of 04:45, 20 July 2014 | ||
23:45, 20 July 2014 | 935 × 965 (229 KB) | Seppi333 (talk | contribs) | recolor | ||
23:34, 20 July 2014 | 935 × 965 (228 KB) | Seppi333 (talk | contribs) | recolor | ||
23:22, 20 July 2014 | 935 × 965 (228 KB) | Seppi333 (talk | contribs) | tweaks and color coding | ||
04:45, 20 July 2014 | 935 × 965 (228 KB) | Seppi333 (talk | contribs) | wider boxes for sirt1/hdac1 again |
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- Amphetamine
- Dextroamphetamine
- Adderall
- Protein c-Fos
- Methamphetamine
- FOSB
- Addiction
- Behavioral epigenetics
- User:Seppi333/sandbox
- Template talk:Annotated image 4
- User talk:Boghog/Archive 8
- Wikipedia talk:WikiProject Molecular Biology/Molecular and Cell Biology/Archive 5
- Wikipedia talk:WikiProject Medicine/Archive 51
- Template:Psychostimulant addiction
- Wikipedia:Featured picture candidates/August-2014
- Wikipedia:Featured picture candidates/ΔFosB
- User:IDidThisForSchool/sandbox
- Talk:MDMA/Archive 5
- Template talk:Addiction glossary
- Wikipedia talk:WikiProject Pharmacology/Archive 8
- Wikipedia talk:Image use policy/Archive 15
- Template:Annotated image 4/transclusions
- User talk:Seppi333/Archive 1
- Talk:Alcoholism/Archive 8
- User:Gallina x/Gather lists/19635 – History of IDEAS
- User:Gallina x/Gather lists/25316 – Madonna
- User:Gallina x/Gather lists/26649 – Female feelings: "To die for" thesis
- User:Gallina x/Gather lists
- User talk:Seppi333/Archive 2
- User:It's gonna be awesome/amphetamines-related
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Width | 935 |
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Height | 965 |