APOD

Protein sy'n cael ei godio yn y corff dynol gan y genyn APOD yw APOD a elwir hefyd yn Apolipoprotein D (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q29.

APOD
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2HZQ, 2HZR
Dynodwyr
Cyfenwau	APOD, Apod, apolipoprotein D
Dynodwyr allanol	OMIM: 107740 HomoloGene: 1246 GeneCards: APOD
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • lipid transporter activity • transporter activity • cholesterol binding • GO:0001948, GO:0016582 protein binding • small molecule binding • lipid binding Cydrannau o'r gell • cytosolic ribosome • intracellular anatomical structure • soma • dendrite • Reticwlwm endoplasmig • perinuclear region of cytoplasm • extracellular exosome • extracellular space • extracellular region • cytoplasm Prosesau biolegol • negative regulation of T cell migration • negative regulation of platelet-derived growth factor receptor signaling pathway • negative regulation of monocyte chemotactic protein-1 production • negative regulation of smooth muscle cell proliferation • tissue regeneration • lipid metabolism • GO:0001315 response to reactive oxygen species • negative regulation of smooth muscle cell-matrix adhesion • GO:0010260 heneiddio • negative regulation of lipoprotein lipid oxidation • brain development • peripheral nervous system axon regeneration • response to axon injury • angiogenesis • glucose metabolic process • negative regulation of focal adhesion assembly • negative regulation of protein import into nucleus • negative regulation of cytokine production involved in inflammatory response • lipid transport • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	347	n/a
Ensembl	ENSG00000189058	n/a
UniProt	P05090	n/a
RefSeq (mRNA)	NM_001647	n/a
RefSeq (protein)	NP_001638	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Llyfryddiaeth

• "ApoD mediates binding of HDL to LDL and to growing T24 carcinoma. ". PLoS One. 2014. PMID 25513803.
• "Lifelong expression of apolipoprotein D in the human brainstem: correlation with reduced age-related neurodegeneration. ". PLoS One. 2013. PMID 24167586.
• "Apolipoprotein D expression does not predict breast cancer recurrence among tamoxifen-treated patients. ". PLoS One. 2017. PMID 28301514.
• "Production of a soluble and functional recombinant apolipoproteinD in the Pichia pastoris expression system. ". Protein Expr Purif. 2016. PMID 26826316.
• "Apolipoprotein D subcellular distribution pattern in neuronal cells during oxidative stress.". Acta Histochem. 2015. PMID 25953740.