MME

Protein sy'n cael ei godio yn y corff dynol gan y genyn MME yw MME a elwir hefyd yn Neprilysin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q25.2.

MME
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1DMT, 1R1H, 1R1I, 1R1J, 1Y8J, 2QPJ, 2YB9, 4CTH, 5JMY
Dynodwyr
Cyfenwau	MME, CALLA, CD10, NEP, SFE, membrane metallo-endopeptidase, membrane metalloendopeptidase, CMT2T, SCA43
Dynodwyr allanol	OMIM: 120520 HomoloGene: 5275 GeneCards: MME
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • zinc ion binding • exopeptidase activity • hydrolase activity • endopeptidase activity • metal ion binding • GO:0070122 peptidase activity • peptide binding • metalloendopeptidase activity • metallopeptidase activity • phosphatidylserine binding • protein homodimerization activity • oligopeptidase activity • cardiolipin binding Cydrannau o'r gell • brush border • focal adhesion • integral component of plasma membrane • cytoplasm • bilen • extracellular exosome • integral component of membrane • synaptic vesicle • Cellbilen • synapse • axon • dendrite • neuron projection terminus • secretory granule membrane • early endosome • trans-Golgi network • cell surface • GO:0016023 cytoplasmic vesicle • soma • membrane raft • presynapse Prosesau biolegol • angiotensin maturation • cellular response to UV-B • cellular response to cytokine stimulus • kidney development • replicative senescence • cellular response to UV-A • creatinine metabolic process • peptide metabolic process • amyloid-beta metabolic process • proteolysis • sensory perception of pain • neutrophil degranulation • placenta development • GO:0010260 heneiddio • learning or memory • lung development • positive regulation of neurogenesis • neuropeptide processing • amyloid-beta clearance • amyloid-beta clearance by cellular catabolic process • positive regulation of long-term synaptic potentiation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4311	n/a
Ensembl	ENSG00000196549	n/a
UniProt	P08473 Q3KQS6	n/a
RefSeq (mRNA)	NM_000902 NM_007287 NM_007288 NM_007289 NM_001354642 NM_001354643 NM_001354644	n/a
RefSeq (protein)	NP_000893 NP_009218 NP_009219 NP_009220 NP_001341571 NP_001341572 NP_001341573	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MME.

• NEP
• SFE
• CD10
• CALLA
• CMT2T
• SCA43

Llyfryddiaeth

• "CD10 down expression in follicular lymphoma correlates with gastrointestinal lesion involving the stomach and large intestine. ". Cancer Sci. 2016. PMID 27513891.
• "Mutations in MME cause an autosomal-recessive Charcot-Marie-Tooth disease type 2. ". Ann Neurol. 2016. PMID 26991897.
• "CD10-Equipped Melanoma Cells Acquire Highly Potent Tumorigenic Activity: A Plausible Explanation of Their Significance for a Poor Prognosis. ". PLoS One. 2016. PMID 26881775.
• "CD10 expression in the neuroendocrine carcinoma component of endometrial mixed carcinoma: association with long survival. ". Diagn Pathol. 2016. PMID 26830028.
• "Haematological profile of 21 patients with hairy cell leukaemia in a tertiary care centre of north India.". Indian J Med Res. 2015. PMID 26609034.