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The role of cyclin E in cell proliferation, development and cancer

  • Chapter
Progress in Cell Cycle Research

Part of the book series: Progress in Cell Cycle Research ((PCCR))

Abstract

Normal cell proliferation is under strict regulation governed by checkpoints located at distinct points in the cell cycle. The deregulation of these checkpoint events and the molecules associated with them may transform a normal cell into a cancer cell. One of these checkpoints whose deregulation results in transformation occurs at the Restriction point, near the G1/S boundary. The periodic appearance of one of the recently identified regulatory cyclins, cyclin E, coincides precisely with the timing of the Restriction point. The deregulation in the expression and activity of cyclin E has been associated with a number of cancers and is thought to be involved in the process of oncogenesis. In this chapter, we summarise the current knowledge on the regulation and apparent function of cyclin E in normal proliferating cells and in developing tissue and alterations of these processes in cancer.

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References

  1. Lew, D. J., Dulic, V., and Reed, S. I. (1991) Cell 66, 1197–1206.

    PubMed  CAS  Google Scholar 

  2. Koff, A., Cross, F., Fisher, A., Schumacher, J., Leguellec, K., Philippe, M., and Roberts, J. M. (1991) Cell 66, 1217–1228.

    PubMed  CAS  Google Scholar 

  3. Cross, F. (1988) Mol. Cell Biol. 8, 4675–4684.

    PubMed  CAS  Google Scholar 

  4. Nash, R., Tokiwa, G., Anand, S., Erickson, K., and Futcher, A. B. (1988) EMBO J. 7, 4335–4346.

    PubMed  CAS  Google Scholar 

  5. Hadwiger, J. A., Wittenberg, C., Richardson, H. E., de Barros Lopes, M., and Reed, S. I. (1989) Proc. Natl Acad. Sci. USA 86, 6255–6259.

    PubMed  CAS  Google Scholar 

  6. Koff, A., Giordano, A., Desiä, D., Yamashita, K., Harper, J. W., Elledge, S. J., Nishomoto, T., Morgan, D. O., Franza, R., and Roberts, J. M. (1992) Science 257, 1689–1694.

    PubMed  CAS  Google Scholar 

  7. Dulic, V., Lees, E., and Reed, S. I. (1992) Science 257, 1958–1961.

    PubMed  CAS  Google Scholar 

  8. Dou, Q.-P., Levin, A. H., Zhao, S., and Pardee, A. B. (1993) Cancer Res. 53, 1493–1497.

    PubMed  CAS  Google Scholar 

  9. Ohtsubo, M., and Roberts, J. M. (1993) Science 259, 1908–1912.

    PubMed  CAS  Google Scholar 

  10. Wimmel, A., Lucibello, F. C, Sewing, A., Adolf, S., and Muller, R. (1994) Oncogene 9, 995–997.

    PubMed  CAS  Google Scholar 

  11. Resnitzky, D., M., G., Bujard, H., and Reed, S. I. (1994) Mol. Cell Biol. 14, 1669–1679.

    PubMed  CAS  Google Scholar 

  12. Ohtsubo, M., Theodoras, A. M., Schumacher, J., Roberts, J. M., and Pagano, M. (1995) Mol. Cell. Biol. 15, 2612–2624.

    PubMed  CAS  Google Scholar 

  13. Tsai, L.-H., Lees, E., Faha, B., Harlow, E., and Riabowol, K. (1993) Oncogene 8, 1593–1602.

    PubMed  CAS  Google Scholar 

  14. Pagano, M., Pepper kok, R., Lukas, J., Baldin, V., Ansorge, W., Bartek, J., and Draetta, G. (1993) J. Cell Biol. 121, 101–111.

    PubMed  CAS  Google Scholar 

  15. van den Heuvel, S., and Harlow, E. (1993) Science 262, 2050–2054.

    PubMed  Google Scholar 

  16. Heichman, K. A., and Roberts, J. M. (1994) Cell 79, 557–562.

    PubMed  CAS  Google Scholar 

  17. Jackson, P. K., Chevalier, S., Philippe, M., and Kirschner, M. W. (1995) J. Cell Bio. 130, 755–769.

    CAS  Google Scholar 

  18. Knoblich, J., Sauer, K., Jones, L., Richardson, H., Saint, R., and Lehner, C. (1994) Cell 77, 107-121.

    PubMed  CAS  Google Scholar 

  19. Krude, T., Jackman, M., Pines, J., and Laskey, R. A. (1997) Cell 88, 109–119.

    PubMed  CAS  Google Scholar 

  20. Mumberg, D., Haas, K., Moroy, T., Niedenthal, R., Hegermann, J. H., Funk, M., and Muller, R. (1996) Oncogene 13, 2493–2497.

    PubMed  CAS  Google Scholar 

  21. Lucibello, F. C, Sewing, A., Brusselback, S., Burger, C, and Muller, R. (1993) J. Cell Science 105, 123–133.

    PubMed  CAS  Google Scholar 

  22. Stein, G. H., and Dulic, V. (1995) BioEssayz 17, 537–543.

    CAS  Google Scholar 

  23. Dulic, V., Drullinger, L., Lees, E., Reed, S., and Stein, G. (1993) Proc. Natl. Acad. Sci. 90, 11034–11038.

    PubMed  CAS  Google Scholar 

  24. Kanazawa, S., Fujiwara, Y., and Mizuno, K. (1994) Kobe J. Med. Sci. 40, 165–174.

    PubMed  CAS  Google Scholar 

  25. Noda, A. F., Ning, Y., Venable, S., Pereira-Smith, O. M., and Smith, J. R. (1994) Exp. Cell. Res. 211, 90–98.

    PubMed  CAS  Google Scholar 

  26. Afshari, C. A., Nichols, M. A., Xiong, Y., and Mudryj, M. (1996) Cell Growth and Diff. 7, 979–988.

    CAS  Google Scholar 

  27. Ohtani, K., DeGregori, J., and Nevins, J. R. (1995) Proc. Natl. Acad. Sci. 92, 12146–12150.

    PubMed  CAS  Google Scholar 

  28. Geng, Y., Eaton, E. N., Picon, M., Roberts, J. M., Lundberg, A. S., Gifford, A., Sardet, C., and Weinberg, R. A. (1996) Oncogene 12, 173–1180.

    Google Scholar 

  29. Herrera, R. E., Sah, V. P., Williams, B. O., Makela, T. P., Weinberg, R. A., and Jacks, T. (1996) Mol. Cell. Biol. 16, 2402–2407.

    PubMed  CAS  Google Scholar 

  30. Solomon, M. J., Lee, T., and Kirschner, M. W. (1992) Mol. Biol. Cell 3, 13–27.

    PubMed  CAS  Google Scholar 

  31. Morgan, D. O. (1995) Nature 374, 131–134.

    PubMed  CAS  Google Scholar 

  32. Desai, D., Wessling, H. C, Fisher, R. P., and Morgan, D. O. (1995) Mol. Cell. Biol. 15, 345–350.

    PubMed  CAS  Google Scholar 

  33. Sauer, K., Knoblich, J. A., Richardson, H., and Lehner, C. F. (1995) Genes & dev. 9, 1327–1339.

    CAS  Google Scholar 

  34. Gu, Y., Turck, C. W., and Morgan, D. O. (1993) Nature 366, 707–710.

    PubMed  CAS  Google Scholar 

  35. Hoffmann, I., Draetta, G., and Karsenti, E. (1994) EMBO J. 13, 4302–4310.

    PubMed  CAS  Google Scholar 

  36. Clurman, B. E., Sheaff, R. J., Thress, K., Groudine, M., and Roberts, J. M. (1996) Genes & Dev. 10, 1979–1990.

    CAS  Google Scholar 

  37. Won, K.-A., and Reed, S. I. (1996) EMBO J. 15, 4182–4193.

    PubMed  CAS  Google Scholar 

  38. El-Deiry, W. S., Harper, J. W., O’Connor, P. M., Velculescu, V. E., Canman, C. E., Jackman, J., Pietenpol, J. A., Burrell, M., Hill, D. E., Wang, Y., Wiman, K. G., Mercer, W. E., Kastan, M. B., Kohn, K. W., Elledge, S. J., Kinzler, K. W., and Vogelstein, B. (1994) Advances in Brieff, 1169–1173.

    Google Scholar 

  39. El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mrcer, W. E., Kinzler, K. W., and Vogelstein, B. (1993) Cell 75, 817–825.

    PubMed  CAS  Google Scholar 

  40. El-Deiry, W. S., T., T., Waldman, T., Oliner, J. D., Velculescu, V. E., Burrell, M., Hill, D. E., Healy, E., Rees, J. L., Hamilton, S. R., Kinzler, K. W., and Vogelstein, B. (1995) Cancer Res. 55, 2910–2919.

    PubMed  CAS  Google Scholar 

  41. Xiong, Y., Hannon, G. J., Zhang, G. J., Gasso, D., Kobayashi, R., and Beach, D. (1993) Nature 366, 710–704.

    Google Scholar 

  42. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., and Elledge, S. J. (1993) Cell 75, 805–816.

    PubMed  CAS  Google Scholar 

  43. Jiang, H., and Fisher, P. B. (1993) Molec. and Cell. Differen. 3, 285–299.

    Google Scholar 

  44. Xiong, Y., Zhang, H., and Beach, D. (1992) Genes & Dev. 7, 1572–1583.

    Google Scholar 

  45. Xiong, Y., Zhang, H., and Beach, D. (1993) Cell 71, 505–514.

    Google Scholar 

  46. Harper, J. W., Elledge, S. J., Keyomarsi, K., Dynlacht, B., Tsai, L.-H., Zhang, P., Dobrowolski, S., Bai, C., Connell-Crowley, L., Swindell, E., Fox, M. P., and Wei, N. (1995) Mol. Biol. Cell 6, 387–400.

    PubMed  CAS  Google Scholar 

  47. Wu, H., Wade, M., Krall, L., Grisham, J., Xiong, Y., and Van Dyke, T. (1996) Genes & Dev. 10, 24–260.

    Google Scholar 

  48. Dulic, V., Kaufman, W. K., Wilson, S., Tlisty, T. D., Lees, E., Harper, J. W., Elledge, S. J., and Reed, S. I. (1994) Cell 76, 1013–1023.

    PubMed  CAS  Google Scholar 

  49. Deng, C., Zhang, P., Harper, J. W., Elledge, S. J., and Leder, P. (1995) Cell 82, 675–684.

    PubMed  CAS  Google Scholar 

  50. Michieli, P., Chedid, M., Lin, D., Pierce, J. H., Mercer, W. E., and Givol, D. (1994) Cancer Res. 54, 3391–3395.

    PubMed  CAS  Google Scholar 

  51. Sheikh, M. S., X., L., Chen, J., Shao, Z., Ordonez, J. V., and Fontana, J. A. (1994), 3407–3415.

    Google Scholar 

  52. Elbendary, A., Berchuck, A., Davis, P., Havrilesky, L., Bast, J., R. C, Iglehart, J. D., and Marks, J. R. (1994) Cell Growth & Diff. 5, 1301–1307.

    CAS  Google Scholar 

  53. Jiang, H., Lin, J., Su, Z., Collart, F. R., Huberman, E., and Fisher, P. B. (1994) Oncogene 9, 3397–3406.

    PubMed  CAS  Google Scholar 

  54. Steinman, R. A., Hoffman, B., Iro, A., Guillouf, C., Liebermann, D. A., and El-Houseini, M. E. (1994) Oncogene 9, 3389–3396.

    PubMed  CAS  Google Scholar 

  55. Jiang, H., Lin, J., Su, A.-z., Collart, F. R., Huberman, E., and Fisher, P. B. (1994) Oncogene 9, 3397–3406.

    PubMed  CAS  Google Scholar 

  56. Zhang, W., Grasso, L., McClain, C. D., Gambel, A. M., Cha, Y., Travali, S., Deisseroth, A. B., and Mercer, W. E. (1995) Cancer Res. 55, 66–674.

    Google Scholar 

  57. Halevy, O., Novitch, B. G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., Beach, D., and Lasser, A. B. (1995) Science 267, 1018–1021.

    PubMed  CAS  Google Scholar 

  58. Parker, S. B., Eichele, G., Zhang, P., Rawls, A., Sands, A. T. Bradley, A., Olsen, E. N., Harper, J. W., and Elledge, S. J. (1995) Science 267, 1024–1027.

    PubMed  CAS  Google Scholar 

  59. Polyak, K., Kato, J.-y., Soloman, M. I., Sherr, C. J., Massague, J., Roberts, J. M., and Koff, A. (1994) Genes & Dev. 8, 9–22.

    CAS  Google Scholar 

  60. Polyak, K., Lee, M.-H., Erdjument-bromage, H., Tempst, P., and Massaague, J. (1994) Cell 78, 59–66.

    PubMed  CAS  Google Scholar 

  61. Toyoshima, H., and Hunter, T. (1994) Cell 78, 67-74.

    PubMed  CAS  Google Scholar 

  62. Hengst, L., Dulic, V., Slingerland, J. M., Lees, E., and Reed, S. I. (1994) Proc. Natl. Acad. Sci. 91, 5291–5295.

    PubMed  CAS  Google Scholar 

  63. Koff, A., Ohtsuki, M., Polyak, K., Roberts, J. M., and Massague, J. (1993) Science 260, 536–539.

    PubMed  CAS  Google Scholar 

  64. Kato, J., Matsuoka, M., Polyak, K., Massague, J., and Sherr, C. J. (1994) Cell 79, 487–496.

    PubMed  CAS  Google Scholar 

  65. Firpo, E. J., Koff, A., Solomon, M. J., and Roberts, J. M. (1994) Mol. Cell Biol. 14, 4889–4901.

    PubMed  CAS  Google Scholar 

  66. Nourse, J., Firpo, E., Flanagan, M., Coats, S., Polyak, C, Lee, M., Massague, J., Crabtree, G., and Roberts, J. (1994) Nature 372, 570–573.

    PubMed  CAS  Google Scholar 

  67. Chen, I., Akamatsu, M., Smith, M. L., Lung, F., Duba, D. Roller, P. P., Fornace, A. J., and O’Connor, P. M. (1996) Oncogene 12, 595–607.

    PubMed  CAS  Google Scholar 

  68. Chen, J., Saha, P., Kornbluth, S., Dynlacht, B. D., and Dutta, A. (1996) Mol. Cell. Biol. 16, 4673–4682.

    PubMed  CAS  Google Scholar 

  69. Adams, P. D., Sellers, W. R., Sharma, S. K., Wu, A. D., Nalin, C. M., and Kaelin, W. G. (1996) Mol. Cell. Biol. 16, 6623–6633.

    PubMed  CAS  Google Scholar 

  70. Lin, J., Reichner, C., Wu, X., and Levine, A. J. (1996) Mol. Cell. Biol. 16, 1786–1793.

    PubMed  CAS  Google Scholar 

  71. Reddy, K. B., Hocevar, B. A., and Howe, P. H. (1994) J. Cell. Biochem. 56, 418–425.

    PubMed  CAS  Google Scholar 

  72. Slingerland, J. M., Hengst, L., Pan, C.-H., Alexander, D., Stampfer, M. R., and Reed, S. I. (1994) Mol. Cell. Biol. 14, 3683–3694.

    PubMed  CAS  Google Scholar 

  73. Mazars, P., Barboule, N., Baldin, V., Vidal, S., Ducommun, B., and Valette, A. (1995) FEBS Lett. 362, 295–300.

    PubMed  CAS  Google Scholar 

  74. Ravitz, M. J., Yan, S., Herr, K. D., and Wenner, C. E. (1995) Can. Res. 55, 1413–1416.

    CAS  Google Scholar 

  75. Gagelin, C, Pierre, M., and Toru-Delbauffe, D. (1994) Biochem. Biophy. Res. Comm. 205, 923–929.

    CAS  Google Scholar 

  76. Watts, C. K., Brady, A., Sarcevic, B., deFazio, A., Musgrove, E. A., and Sutherland, R. L. (1995) Molec. Endoc. 9, 1804–1813.

    CAS  Google Scholar 

  77. Foster, J. S., and Wimalasena, J. (1996) Molec. Endro. 10, 488–498.

    CAS  Google Scholar 

  78. Fang, F., Orend, G., Watanabe, N., Hunter, T., and Ruoslahti, E. (1996) Science 271, 499–502.

    PubMed  CAS  Google Scholar 

  79. Carstens, C.-P., Kramer, A., and Fahl, W. E. (1996) Exp. Cell Res. 229, 86–92.

    PubMed  CAS  Google Scholar 

  80. Guadagno, T. M., Ohtsubo, M., Roberts, J. M., and Assoian, R. (1993) Science 262, 1572–1575.

    PubMed  CAS  Google Scholar 

  81. Schulze, A., Zerfass-Thome, K., Berges, J., Middendorp, S., Jansen-Durr, P., and Henglein, B. (1996) Mol. Cell Biol. 16, 4632–4638.

    PubMed  CAS  Google Scholar 

  82. Schulze, A., Zerfaß, K., Spitkovsky, D., Berges, J., Middendorp, S., Jansen-Durr, P., and Henglein, B. (1995) Proc. Natl Acad. Sci. 92, 11264–11268.

    PubMed  CAS  Google Scholar 

  83. Zhu, X., Ohtsubo, M., Böhmer, R. M., Roberts, J. M., and Assoian, R. K. (1996) J. Cell Biol. 133, 391–403.

    PubMed  CAS  Google Scholar 

  84. Tikoo, R., Casaccia-Bonnefil, P., Chao, M. V. and Koff, A. (1997) J. Biol Chem. 272, 442–447.

    PubMed  CAS  Google Scholar 

  85. Bruno, S., Ardelt, B., Skierski, J. S., Tragónos, F. and Darzynkiewicz, Z. (1992) Cancer Res. 52, 470–473.

    PubMed  CAS  Google Scholar 

  86. Abe, K., Yoshida, M., Usui, T., Horinouchi, S. and Beppu, T. (1991) Exp. Cell Res. 192, 1–6.

    Google Scholar 

  87. Crissman, H. A., Gadbois, D. M., Tobey, R. A., and Bradbury, E. M. (1991) Proc. Natl Acad. Sci. USA 88, 7580–7584.

    PubMed  CAS  Google Scholar 

  88. Schnier, J. B., Gadbois, D. M., Nishi, K., and Bradbury, E. M. (1994) Cancer Res. 54, 5959–5963.

    PubMed  CAS  Google Scholar 

  89. Gong, J., Tráganos, F., and Darznkiewicz, Z. (1994) Cancer Res. 54, 3136–3139.

    PubMed  CAS  Google Scholar 

  90. Kwon, T. K., Buchholz, M. A., Chrest, F. J., and Nordin, A. A. (1996) Cell Growth & Dif. 7, 1305–1313.

    CAS  Google Scholar 

  91. Schnier, J. B., Nishi, K., Goodrich, D. W., and Bradbury, E. M. (1996) Proc. Natl Acad. Sci. 93, 5941–5946.

    PubMed  CAS  Google Scholar 

  92. Kaur, G., Stetler-Stevenson, M., Sebers, S., Worland, P., Sedlacek, H., Myers, C., Czech, J., Naik, R., and Sausville, E. (1992) J. Natl. Can. Ins. 84, 1736–1740.

    CAS  Google Scholar 

  93. Carlson, B. A., Dubay, M. M., Sausville, E. A., Brizuela, L., and Worland, P. J. (1996) Cancer Res. 56, 2973–2978.

    PubMed  CAS  Google Scholar 

  94. Deazevedo, W. F., Leclerc, S., Meijer, L., Havlicek, L., Strnad, M., and Kim, S. H. (1997) Eur. J. Bioch. 243, 518–526.

    CAS  Google Scholar 

  95. Meijer, L., Borgne, A., Mulner, O., Chong, J. P. J., Blow, J. J., Inagaki, N., Inagaki, M., Delcros, J. G., and Moulinoux, J. P. (1997) Euor. J. Biochem. 243, 527–36.

    CAS  Google Scholar 

  96. Hatakeyama, M., Brill, J. A., Fink, G. R., and Weinberg, R. A. (1994) Genes & Dev. 8, 1759–1771.

    CAS  Google Scholar 

  97. Hinds, P. W., Mittnacht, S., Dulic, V., Arnold, A., Reed, S. I., and Weinberg, R. A. (1992) Cell 70, 993–1006.

    PubMed  CAS  Google Scholar 

  98. Chen, P.-L., Scullly, P., Shew, J.-Y., Wang, J. Y. J., and Lee, W.-H. (1989) Cell 58, 1193–1198

    PubMed  CAS  Google Scholar 

  99. Weinberg, R. A. (1995) Cell 81, 323–330.

    PubMed  CAS  Google Scholar 

  100. Dowdy, F. D., Hinds, P. W., Louie, K., Reed, S. I., and Weinberg, R. A. (1993) Cell 73, 499–511.

    PubMed  CAS  Google Scholar 

  101. Ewen, M. E., Sluss, H. K., Sherr, C. J., Natsushime, H., Kato, J.-Y., and Livingston, D. M. (1993) Cell 73, 487–497.

    PubMed  CAS  Google Scholar 

  102. Kato, J.-Y., Matsushime, H., Hiebert, S. W., Ewen, M. E., and Sherr, C. J. (1993) Genes Dev. 7, 331–342.

    PubMed  CAS  Google Scholar 

  103. Lukas, J., Bartkova, J., Rohde, M., Strauss, M., and Bartek, J. (1995) Mol. Cell Bio. 15, 2600–2611.

    CAS  Google Scholar 

  104. Resnitzky, D., and Reed, S. I. (1995) Mol. Cell Bio. 15, 3463–3469.

    CAS  Google Scholar 

  105. Bremner, R., Cohen, B. L., Sopta, M., Hamel, P. A., Ingles, C. J., Gallie, B. L., and Phillips, R. A. (1995) Mol. Cell. Biol. 15, 3256–3265.

    PubMed  CAS  Google Scholar 

  106. Lees, E., Faha, B., Dulic, V., Reed, S. I., and Harlow, E. (1992) Genes Dev. 6, 1874–1855.

    PubMed  CAS  Google Scholar 

  107. Beijersbergen, R. L., Carlee, L., Kerkhoven, R. M., and Bernards, R. (1995) Genes & Dev. 9, 1340–1353.

    CAS  Google Scholar 

  108. Xiao, Z.-X., Ginsberg, D., Ewen, M., and Livingston, D. M. (1996) Proc. Natl Acad. Sci. 93, 4633–4637.

    PubMed  CAS  Google Scholar 

  109. Zhu, L., Enders, G., Lees, J. A., Beijersbergen, R. L., Bernards, R., and Harlow, E. (1995) EMBO J. 14, 1904–1913.

    PubMed  CAS  Google Scholar 

  110. Li, Y., Graham, C, Lacy, S., Duncan, A. M. V., and Whyte, P. (1993) Genes & Dev. 7, 2366–2377.

    CAS  Google Scholar 

  111. Richardson, H., O’Keefe, L. V., Marty, T., and Saint, R. (1995) Development 121, 3371–3379.

    PubMed  CAS  Google Scholar 

  112. Lilly, M. A., and Spradling, A. C. (1996) Genes & Dev. 10, 2514–2526.

    CAS  Google Scholar 

  113. Edgar, B. (1995) Curr. Opin. Cell Biol. 7, 815–824.

    PubMed  CAS  Google Scholar 

  114. Edgar, B. A., Sprenger, F., Duronio, R. J., P., L., and O’Farrell, P. H. (1994) Genes & Dev. 8, 440–453.

    CAS  Google Scholar 

  115. Edgar, B. A., and O’Farrell, P. H. (1990) Cell 62, 469–480.

    PubMed  CAS  Google Scholar 

  116. Foe, V. E., O’Dell, G. M., and Edgar, B. A. (1993) in THe development of Drosophila melanogaster (Bate, M., and Martinez-Arias, A., eds), pp. 149–300, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, USA.

    Google Scholar 

  117. Richardson, H. E., O’Keefe, L. V., Reed, S. I., and Saint, R. (1993) Development 119, 673–690.

    PubMed  CAS  Google Scholar 

  118. Edgar, B. A. (1994) Current Biol. 4, 522–524.

    CAS  Google Scholar 

  119. Chevalier, S., Couturier, A., Chartrain, I., Le Guellec, R., Beckhelling, C., Le Guellec, K., Philippe, M., and Ford, C. C. (1996) J. Cell Science 109, 1173–1184.

    PubMed  CAS  Google Scholar 

  120. Botz, J., Zerfass-Thome, K., Spitkobvsky, D., Delius, H., Vogt, B., Eilers, M., Hatzigeorgiou, A., and Jansen-Durr, P. (1996) Mol. Cell. Biol. 16, 3401–3409.

    PubMed  CAS  Google Scholar 

  121. Yarden, A., and Geiger, B. (1996) Dev. Dynamics 206, 1–11.

    CAS  Google Scholar 

  122. Strausfeld, U. P., howell, M., Descombes, P., Chevalier, S., Rempel, R. E., Adamczewski, J., Mailer, J. L., Hunt, T., and Blow, J. J. (1996) J. Cell Science 109, 1555–1563.

    PubMed  CAS  Google Scholar 

  123. Duronio, R. J., and O’Farrell, P. H. (1994) Development 120, 1503–1515.

    PubMed  CAS  Google Scholar 

  124. Marini, N. J., and Reed, S. J. (1992) Genes & Dev. 6, 557–567.

    CAS  Google Scholar 

  125. Dirick, l., and Nasmyth, K. (1991) Nature 351, 754–757.

    PubMed  CAS  Google Scholar 

  126. Rempel, R. E., Sleight, S. B., and Mailer, J. L. (1995) J. Biol. Chem. 270, 6843–6855.

    PubMed  CAS  Google Scholar 

  127. Du, W., Vidal, M., Xie, J.-E., and Dyson, N. (1996) Genes & Dev. 10, 1206–1218.

    CAS  Google Scholar 

  128. Lane, M. E., Sauer, K., Wallace, K., Jan, Y. N., Lehner, C. F., and Vaessin, H. (1996) Cell 87, 1225–1235.

    PubMed  CAS  Google Scholar 

  129. De Nooij, J. C, Letendre, M. A., and Hariharan, I. K. (1996) Cell 87, 1237–1247.

    PubMed  Google Scholar 

  130. Follette, P. J., and OTarrell, P. H. (1997) Curr. Op. Gen. &Dev. 7, 17–22.

    CAS  Google Scholar 

  131. Howe, J. A., and Newport, J. W. (1996) Proc. Natl Acad. Sei 93, 2060–2064.

    CAS  Google Scholar 

  132. Ashworth, L. K., Batzer, M. A., Brandriff, B., Branscomb, E., de Jong, P., Garcia, E., Garnes, J. A., Gordon, L. A., Lamerdin, J. E., Lennon, G., Mohrenweiser, H., Olsen, A., Slezak, T., and Carraón, A. V. (1995) Nat. Genet. 11, 422–427.

    PubMed  CAS  Google Scholar 

  133. Li, H., Lahti, J. M., Valentine, M., Saito, M., Reed, S. I., Look, A. T., and Kidd, V. J. (1996) Genomics 32, 253–259.

    PubMed  CAS  Google Scholar 

  134. Demetrick, D. J., Matsumoto, S., Hannon, G. J., Okamoto, K., Xiong, Y., Zhang, H., and Beach, D. H. (1995) Cytogne. Cell Genet. 69, 19–192.

    Google Scholar 

  135. Johnson, D. K., Stubbs, L. J., and DeLoia, J. A. (1996) Mamm. Gen. 7, 245.

    CAS  Google Scholar 

  136. Keyomarsi, K., and Pardee, A. B. (1993) Proc. Natl Acad. Sci. USA 90, 1112–1116.

    PubMed  CAS  Google Scholar 

  137. Sewing, A., Ronicke, V., Burger, C, Funk, M., and Muller, R. (1994) J. Cell Science 107, 581–588.

    PubMed  CAS  Google Scholar 

  138. Keyomarsi, K., Conte, D., Toyofuku, W., and Fox, M. P. (1995) Oncogene 11, 941–950.

    PubMed  CAS  Google Scholar 

  139. Keyomarsi, K., O’Leary, N., Molnar, G., Lees, E., Fingert, H. J., and Pardee, A. B. (1994) Cancer Res. 54, 380–385.

    PubMed  CAS  Google Scholar 

  140. Buckley, M. F., Sweeney, K. J. E., Hamilton, J. A., Sini, R. L., Manning, D. L., Nicholson, R. I., deFazio, A., Watts, C. K. W., Musgrove, E. A., and Sutherland, R. L. (1993) Oncogene 8, 2127–2133.

    PubMed  CAS  Google Scholar 

  141. Dutta, A., Chandra, R., Leiter, L. M., and Lester, S. (1995) Proc. Natl. Acad. Sci. 92, 5386–5390.

    PubMed  CAS  Google Scholar 

  142. Nielsen, N. H., Arnerlov, C, Emdin, S. O., and Landberg, G. (1996) Brit. J. Cane. 74, 874–880.

    CAS  Google Scholar 

  143. Porter, P. L., Malone, K. E., Heagerty, P. J., Alexander, G. M., Gatti, L. A., Firpo, E. J., Daling, J. R., and Roberts, J. M. (1997) Nat. Med. 3, 222–225.

    PubMed  CAS  Google Scholar 

  144. Steeg, P. S., and Abrams, J. S. (1997) Nat. Med. 3, 152–154.

    PubMed  CAS  Google Scholar 

  145. Dou, Q.-P., Pardee, A. B., and Keyomarsi, K. (1996) Nature Med. 2, 254.

    PubMed  CAS  Google Scholar 

  146. Leach, S. F., Elledge, S. J., Sherr, C. J., Willson, J. K. V., Markowitz, S., Kinzler, K. W., and Vogelstein, B. (1993) Cancer Res. 53, 1986–1989.

    PubMed  CAS  Google Scholar 

  147. Akama, Y., Yasui, W., Yokozaki, H., Kuniyasu, H., Kitahara, K., Ishikawa, T., and Tahara, E. (1995) Jpn. J. Cancer res. 86, 617–621.

    PubMed  CAS  Google Scholar 

  148. Kitahara, K., Yasui, W., Kuniyasu, H., Yokozaki, H., Akama, Y., Yunotani, S., Hisatsugu, T., and Tahara, E. (1995) Int. J. Cancer 62, 25–28.

    PubMed  CAS  Google Scholar 

  149. Courjal, F., Louason, G., Speiser, P., Katsaros, D., Zeillinger, R., and Theillet, C. (1996) Int. J. Cancer 69, 247–253.

    PubMed  CAS  Google Scholar 

  150. Wang, A., Yoshimi, N., Suzui, M., Yamauchi, A., Tarao, M., and Mori, H. (1996) J. Cancer Res. Clin. Oncol. 122, 122–126.

    PubMed  CAS  Google Scholar 

  151. Scuderi, R., Palucka, K. A., Pokrovskaja, K., Björkholm, M., Wiman, K. G., and Pisa, P. (1996) Blood 8, 3360–3367.

    Google Scholar 

  152. Yasui, W., Kuniyasu, H., Yokozaki, H., Semba, S., Shimamoto, F., and Tahara, E. (1996) Virchows Arch. 429, 13–19.

    PubMed  CAS  Google Scholar 

  153. Mashal, R. D., Lester, S., Corless, C., Richie, J. P., Chandra, R., Propert, K. J., and Dutta, A. (1996) Cancer Res. 56, 4159–4163.

    PubMed  CAS  Google Scholar 

  154. Wolowiec, D., Benchaib, M., Pernas, P., Deviller, P., Souchier, C., Rimokh, R., Felman, P., Bryon, P. A., and Ffrench, M. (1995) Leukemia 9, 1382–1388.

    PubMed  CAS  Google Scholar 

  155. Wang, Q.-S., Sabourin, C. L. K., Wang, H., and Stoner, G. (1996) Cacinog. 17, 1583–1588.

    CAS  Google Scholar 

  156. Sgambato, A., Han, E. K., Zhang, Y., Moon, R. C, Santella, R. M., and Weinstein, I. B. (1995) Carcinogenesis 16, 2193–2198.

    PubMed  CAS  Google Scholar 

  157. Gray-Bablin, J., Zalvide, J., Fox, M. P., Knickerbocker, C. J., DeCaprio, J. A., and Keyomarsi, K. (1996) Proc. Natl. Acad. Sci. 93, 15215–15220.

    PubMed  CAS  Google Scholar 

  158. Shapiro, G. I., Edwards, C. D., Kobzik, L., Godleski, J., Richards, W., Sugarbaker, D. J., and Rollins, B. J. (1995) Cancer REs. 55, 505–509.

    PubMed  CAS  Google Scholar 

  159. Aagaard, L., Lukas, J., Bartkovva, J., Kjerulff, A.-A., Strauss, M., and Bartek, J. (1995) Int. J. Cancer 61, 115–120.

    PubMed  CAS  Google Scholar 

  160. Otterson, G. A., Kratzke, R. A., Coxoon, A., Kim, Y. W., and Kaye, F. J. (1994) Oncogene 9, 3375–3378.

    PubMed  CAS  Google Scholar 

  161. Parry, D., Bates, S., Mann, D. J., and Peters, G. (1995) EMBO J. 14, 503-511.

    PubMed  CAS  Google Scholar 

  162. Tarn, S. W., Shay, J. W., and Pagano, M. (1994) Cancer Res. 54, 5816–5820.

    Google Scholar 

  163. Nielsen, N. H., emdin, S. O., Cajander, J., and Landberg, G. (1997) Oncogene 14, 295–304.

    PubMed  CAS  Google Scholar 

  164. Bortner, D. M., and Rosenberg, M. P. (1996) Mol. Cell Bio. 17, 453–459.

    Google Scholar 

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  1. Wadsworth Center, New York State Department of Health, Empire State Plaza, P.O. Box 509, Albany, NY, 12201, USA

    Khandan Keyomarsi & Thaddeus W. Herliczek

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  1. Khandan Keyomarsi
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  1. Centre National de la Recherche Scientifique, Roscoff, France

    Laurent Meijer  & Silvana Guidet  & 

  2. Centre National de la Recherche Scientifique, Université de Rennes I, Rennes, France

    Michel Philippe

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Keyomarsi, K., Herliczek, T.W. (1997). The role of cyclin E in cell proliferation, development and cancer. In: Meijer, L., Guidet, S., Philippe, M. (eds) Progress in Cell Cycle Research. Progress in Cell Cycle Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5371-7_14

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