Summary
The dose dependent effects of position-effect variegation (PEV) modifying genes were studied in chromosome arms2L, 2R and3R. Four groups of PEV modifying genes can be distinguished: haplo-abnormal suppressor and enhancer loci with or without a triplo-effect. using duplications four triplo-abnormal suppressor and four triplo-abnormal enhancer functions were localized. In two cases we proved that these functions correspond to a converse haplo-abnormal one. Altogether 43 modifier loci were identified. Most of these loci proved not to display significant triplo-effects (35). The group of haplo-abnormal loci with a triplo-effect may represent genes which play an important role in heterochromatin packaging.
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Communicated by J.A. Campos-Ortega
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Wustmann, G., Szidonya, J., Taubert, H. et al. The genetics of position — effect variegation modifying loci inDrosophila melanogaster . Molec. Gen. Genet. 217, 520–527 (1989). https://doi.org/10.1007/BF02464926
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DOI: https://doi.org/10.1007/BF02464926