Abstract
Trans fatty acids have the presence of one or more double bonds in the trans configuration instead of the usual cis configuration. They are desired by Vanaspati industry as they impart firmness to margarines and plasticity as well as emulsion stability to shortenings. Research has proved the direct connection of trans fatty acids with cardiovascular diseases, breast cancer, shortening of pregnancy period, risks of preeclampsia, disorders of nervous system and vision in infants, colon cancer, diabetes, obesity and allergy. In light of these new findings trans fatty intake should be zero and new technology of hydrogenation of oils is to be developed which produce zero trans fatty acids at the same time preserve the desirable properties contributed by trans fatty acids to the hydrogenated oils. Presently in India there is no system to monitor and regulate the amount of trans fats in processed foods and hence a stringent food law is immediately required.
Similar content being viewed by others
References
Aggarwal A, Gupta R, Varma K, Mathur B (2008) High trans fatty acid content in common Indian fast foods. Nutr Food Sci 38(6):564–569
Aro A, Jauhiainen M, Partanen R, Salminen I, Mutanen M (1997) Stearic acid, trans fatty acids, and dairy fat: effects on serum and lipoprotein lipids, apolipoproteins, lipoprotein (a), and lipid transfer proteins in health subjects. Am J Clin Nutr 65:1419–1426
Ascherio A, Hennekens CH, Buring JE, Master C, Stampfer MJ, Willett WC (1994) Trans fatty acid intake and risk of myocardial infarction. Circulation 89:94–101
Berghaus TM, Demmelmair H, Koletzko B (1998) Fatty acid composition of lipid classes in maternal and cord Plasma at birth. Eur J Pediatr 157:763–768
Caggiula AW, Mustad VA (1997) Effects of dietary fat and fatty acids on coronary artery disease risk and total and lipoprotein cholesterol concentrations: epidemiologic studies. Am J Clin Nutr 65:1597S–1610S
Elias SL, Innis SM (2001) Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. Am J Clin Nutr 73:807–814
FSSA (2010) Food Safety and Standards Authority of India Proposes Regulation of Trans Fatty Acids (TFAs) in Partially Hydrogenated Vegetable Oils (PHVOs) http://www.fssai.gov.in/Website/LinkClick.aspx?fileticket=SvU1nfLZRrc%3D&tabid=94. Accessed 10 November 2010
Ghafoorunissa G (2008) Role of trans fatty acids in health and challenges to their reduction in Indian foods. Asia Pac J Clin Nutr 17:212–215
Gould AL, Rossouw JE, Santanello NC, Heyse FJ, Furberg CD (1998) Cholesterol reduction yields clinical benefit: impact of stain trials. Circulation 97:946–952
Hornstra G (2000) Essential fatty acids in mothers and their neonates. Am J Clin Nutr 71:1262S–1269S
Hunter JE (2001) Studies on effects of dietary fatty acids as related to their position on triglycerides. Lipids 36:655–668
Judd JT, Clevidence BA, Muesing RA, Wittes J, Sunkin ME, Podczasy JJ (1994) Dietary trans fatty acids: effects of plasma lipids and lipoproteins on healthy men and women. Am J Clin Nutr 59:861–868
Kavanagh K, Jones KL, Sawyer J, Kelley K, Carr JJ, Wagner JD, Rudel LL (2007) Trans fat diet induces abdominal obesity and changes in insulin sensitivity in monkeys. Obes Res 15:1675–1684
Keys A (1980) Coronary heart disease, serum cholesterol, and the diet. Acta Med Scand 207:153–160
Kohlmeier L, Simonsen N, Van’t Veer P et al (1997) Adipose tissue trans fatty acids and breast cancer in the European community multicenter study on antioxidants, myocardial infarction, and breast cancer. Cancer Epidemiol Biomark Prev 6(9):705–710
Koletzko B (1992) Trans fatty acids may impair biosynthesis of long-chain polyunsaturates and growth in man. Acta Paediatr 81:302–306
Kromhout D, Lezenne CC (1984) Diet, prevalence and 10-year mortality from coronary heart disease in 871 middle-aged men Zutphen Study. Am J Epidemiol 119:733–741
Lichtenstein AH, Ausman LM, Jalbert SM, Schaefer EJ (1999) Effects of different forms of dietary hydrogenated fats on serum lipoprotein cholesterol levels. N Engl J Med 340:1933–1940
Liu WH, Stephen Inbaraj B, Chen BH (2007) Analysis and formation of trans fatty acids in hydrogenated soyabean oil during heating. Food Chem 104(4):1740–1749
Meijer GW, Weststrate JA (1997) Interesterification of fats in margarine: effect on blood lipids, blood enzymes, and hemostasis parameters. Eur J Clin Nutr 51:527–534
Mensink RP (2005) Metabolic and health effects of isomeric fatty acids. Curr Opin Lipidol 16:27–30
Mensink RP, Katan MB (1990) Effect of dietary trans fatty acids on high-density and low density lipoprotein cholesterol levels in healthy subjects. N Engl J Med 323:439–445
Meyer KA, Kushi LH, Jacobs DR, Folsom AR (2001) Dietary fat and incidence of type II diabetes in older Iowa women. Diabetes Care 24:1528–1535
Mozaffarian D, Katan MB, Ascherio A, Stampfer MJ, Willett WC (2006) Trans fatty acids and cardiovascular disease. N Engl J Med 354:1601–1613
Mozaffarian D, Aro A, Willett WC (2009) Health effects of trans-fatty acids: experimental and observational evidence. Eur J Clin Nutr 63(2):S5–S21
Nestel PJ, Noakes M, Belling GB, McArthur R, Clifton PM (1995) Effect on plasma lipids of interesterifying a mix of edible oils. Am J Clin Nutr 62:950–955
Olsen SF, Sørensen JD, Secher NJ, Hedegaard M, Henriksen TB, Hansen HS, Grant A (1992) Randomised controlled trial of effect of fish-oil supplementation on pregnancy duration. Lancet 339:1003–1007
Pax J, Douglass L, Sampugna J (1992) Effects of linolenic and trans-fattyadics on neonatal survival of C57BL/6 Mice. J Nutr Biochem 3(7):342–348
Ricerus U, Arner P, Brismar K, Vessby B (2002) Treatment with dietary trans10- cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome. Diabetes Care 25:1516–1521
Salmeron J, Hu FB, Manson JE, Stampfer MJ, Colditz GA, Rimm EB, Willett WC (2001) Dietary fat intake and risk of type II diabetes in women. Am J Clin Nutr 73:1019–1026
Skeaff CM (2009) Feasibility of recommending certain replacement or alternative fats. Eur J Clin Nutr 63:S34–S49
Slattery ML, Benson J, Ma KN, Schaffer D, Potter JD (2001) Trans-fatty acids and colon cancer. Nutr Cancer 39(2):170–175
Stender S, Dyerberg J, Hølmer G, Ovesen L, Sandström B (1994) Transfedtsyrers betydning for sundheden. A report from the Danish Nutrition Council. Publ No. 2. Copenhagen 1994
Sugano M, Ikeda I (1996) Metabolic interactions between essential and trans-fatty acids. Curr Opin Lipidol 7:38–42
Tsuzuki W (2010) Cis–trans isomerization of carbon double bonds in monounsaturated triacylglycerols via generation of free radicals. Chem Phys Lipids 163:741–745
Wahle KWJ, James WPT (1993) Isomeric fatty acids and human health. Eur J Clin Nutr 47:828–839
Weggemans RM, Rudrum M, Trautwein EA (2004) Intake of ruminant versus industrial trans fatty acids and risk of coronary heart disease—what is the evidence? Eur J Lipid Sci Technol 106:390–397
Weiland SK, von Mutius E, Hüsing A, Asher MI (1999) On behalf of the ISAAC Steering Committee. Intake of trans fatty acids and prevalence of childhood asthma and allergies in Europe. Lancet 353:2040–2041
Willett WC, Stampfer MJ, Manson JE, Colditz GA, Speizer FE, Rosner BA, Sampson LA, Hennekens CH (1993) Intake of trans fatty acids and risk of coronary heart disease among women. Lancet 341:581–585
Williams MA, King IB, Sorensen TK, Zingheim RW, Troyer BL, Zebelman AM, Luthy DA (1998) Risk of preeclampsia in relation to elaidic acid (Trans Fatty Acid) in maternal erythrocytes. Gynecol Obstet Investig 46:84–87
Yli-Jama P, Meyer HE, Ringstad J, Pedersen JI (2002) Serum free fatty acid pattern and risk of myocardial infarction: a case-control study. J Intern Med 251:19–28
Zock PL, Vries JHM, Fouw NJ, Katan MB (1995) Positional distribution of fatty acids in dietary triglycerides: effects on fasting blood lipoprotein concentrations in humans. Am J Clin Nutr 61:48–55
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Dhaka, V., Gulia, N., Ahlawat, K.S. et al. Trans fats—sources, health risks and alternative approach - A review. J Food Sci Technol 48, 534–541 (2011). https://doi.org/10.1007/s13197-010-0225-8
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13197-010-0225-8