Abstract
A HIGHLY sensitive radioimmunoassay has been developed for human spectrin, one of the major components of the erythrocyte membrane1–6. We report here use of this assay on cells of human, monkey and rat origin and show that spectrin is absent from all cell lines studied, with the exception of erythrocytes. These findings seem important when models which invoke spectrin to regulate membrane fluidity,7,8 or membrane-cytoskeletal interaction9,10 are considered.
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HILLER, G., WEBER, K. Spectrin is absent in various tissue culture cells. Nature 266, 181–183 (1977). https://doi.org/10.1038/266181a0
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DOI: https://doi.org/10.1038/266181a0
