C-type lectin domain family 9 member A is a protein that in humans is encoded by the CLEC9A gene.[5]
| CLEC9A | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | CLEC9A, DNGR1, UNQ9341, CD370, DNGR-1, C-type lectin domain family 9 member A, C-type lectin domain containing 9A | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 612252; MGI: 2444608; HomoloGene: 52106; GeneCards: CLEC9A; OMA:CLEC9A - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
editCLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[6]
References
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000197992 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046080 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: C-type lectin domain family 9 member A". Retrieved 2016-06-02.
- ^ Zanders, Edward D. (2015-11-09). Human Drug _targets: A Compendium for Pharmaceutical Discovery. John Wiley & Sons. ISBN 978-1-118-84985-9.
Further reading
edit- Huysamen C, Willment JA, Dennehy KM, Brown GD (2008). "CLEC9A is a novel activation C-type lectin-like receptor expressed on BDCA3+ dendritic cells and a subset of monocytes". J. Biol. Chem. 283 (24): 16693–701. doi:10.1074/jbc.M709923200. PMC 2562446. PMID 18408006.
External links
edit- PDBe-KB provides an overview of all the structure information available in the PDB for Human C-type lectin domain family 9 member A (CLEC9A)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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