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Summary
| Description |
English: After initial binding of the ACE2 receptor, SARS-CoV spike is proteolytically activated and enzymatically cleaved at the S1/S2 level. S1 than dissociates from S2 and the truncated 2 subunit of the Spike protein facilitates fusion of viral and cellular membranes. |
| Date | |
| Source |
Rossi, G.A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020). https://doi.org/10.1007/s15010-020-01486-5 |
| Author | Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani, and Fabio Midulla |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 08:01, 1 February 2021 | | 1,502 × 612 (91 KB) | Guest2625 | Uploaded a work by Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani, and Fabio Midulla from Rossi, G.A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020). https://doi.org/10.1007/s15010-020-01486-5 with UploadWizard |
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