BY FREEMAN J. BUMSTEAD, M.D., Professor of Venereal Diseases at the College of Physicians and Surgeons, New York, etc. CAROLINE MEYER, German, æt. 24, was admitted into Charity Hospital, Blackwell's Island, in January, 1868. She reported that, three years before, she contracted a chancre upon the right labium majus, which was cauterized. In spite of reiterated questions, she affirmed that she had never had any eruption until three weeks ago, when the present erup- tion-one of ecthyma—appeared upon the scalp, face, arms, and breast. Cicatrices, however, of an older eruption were found upon various parts of the integument, and of what were proba- bly condylomata in the neighborhood of the genital organs. A year since an enlargement appeared at the upper commissure of the vulva, and continued to increase until two or three months ago, when it became stationary. The growth is larger or smaller, according to the length of time she has been standing or sitting. It is never painful except in warm weather, when