Fluoroacetamide is an organic compound with the chemical formula FCH2CONH2. It is a compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. It is very toxic.[1] It is a metabolic poison which disrupts the citric acid cycle and was used as a rodenticide.[2] May cause reproductive disorders. If swallowed or in contact with skin, it can cause serious damage and death. Can cause serious eye damage.[1]
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| Names | |
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| IUPAC name
2-Fluoroacetamide
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.010.331 |
| KEGG | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| FCH2CONH2 | |
| Molar mass | 77.058 g·mol−1 |
| Appearance | Colorless crystals |
| Melting point | 107 to 109 °C (225 to 228 °F; 380 to 382 K) |
| Soluble | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
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Very toxic |
| GHS labelling: | |
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| Danger | |
| H300+H310 | |
| P262, P264, P270, P280, P301+P310+P330, P302, P350, P362, P405, P501 | |
| NFPA 704 (fire diamond) | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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80 mg/kg (dermal, rat) |
LC50 (median concentration)
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550 mg/m3(mouse, inhalation, dust/mist) |
| Safety data sheet (SDS) | [1] |
| Related compounds | |
Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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See also
editReferences
edit- ^ a b c https://www.sigmaaldrich.com/US/en/sds/aldrich/128341?userType=anonymous [bare URL]
- ^ MATSUMURA F, O'BRIEN RD. A COMPARATIVE STUDY OF THE MODES OF ACTION OF FLUOROACETAMIDE AND FLUOROACETATE IN THE MOUSE AND AMERICAN COCKROACH. Biochem Pharmacol. 1963 Oct;12:1201-5.doi:10.1016/0006-2952(63)90095-9 PMID 14074120
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