Fumigaclavine B O-acetyltransferase (EC 2.3.1.205, FgaAT) is an enzyme with systematic name acetyl-CoA:fumigaclavine B O-acetyltransferase.[1] This enzyme catalyses the following chemical reaction
| Fumigaclavine B O-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.205 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- acetyl-CoA + fumigaclavine B CoA + fumigaclavine A
The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid.
References
edit- ^ Liu X, Wang L, Steffan N, Yin WB, Li SM (September 2009). "Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B". ChemBioChem. 10 (14): 2325–8. doi:10.1002/cbic.200900395. PMID 19672909.
External links
edit- Fumigaclavine+B+O-acetyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
