Morgan Hwa-Tze Sheng is a professor of neurobiology and a Core Institute Member at the Broad Institute, where he is a co-director of the Stanley Center for Psychiatric Research at Broad Institute.[1] He is a professor of neuroscience in the Department of Brain and Cognitive Sciences as well as the Menicon Professor of Neuroscience at Massachusetts Institute of Technology.[2] He is also an associate member at both The Picower Institute for Learning and McGovern Institute for Brain Research.[3] He has served on the editorial boards of Current Opinions in Neurobiology, Neuron, and The Journal of Neuroscience.[4]
PhD Morgan Sheng | |
|---|---|
 | |
| Born | February 23, 1958 |
| Education | PhD in molecular genetics |
| Alma mater | Harvard University |
| Scientific career | |
| Fields | Synaptic plasticity, neurodegeneration, therapeutics, psychiatric disorders |
| Institutions | Stanley Center for Psychiatric Research at Broad Institute, McGovern Institute for Brain Research, Massachusetts General Hospital, Harvard Medical School, Genentech, Howard Hughes Medical Institute |
| Doctoral advisor | Michael E. Greenberg |
| Notable students | Casper Hoogenraad |
| Website | Sheng Lab |
Education
editSheng received a PhD in molecular genetics from Harvard University.
Career
editHis postdoc was performed at the University of California, San Francisco.[5] Following that, Sheng was an assistant professor and associate professor at the Massachusetts General Hospital and Harvard Medical School, an investigator at the Howard Hughes Medical Institute,[6] professor of neuroscience at Massachusetts Institute of Technology, and vice president of neuroscience at Genentech.[7][8][9] His research has focused on pathogenic mechanisms of neurodegenerative diseases and molecular cellular biology of synapses and synaptic plasticity.[10]
Honors and awards
edit
- 2023: Member, National Academy of Medicine[11][12]
- 2020: Julius Axelrod Prize, Society for Neuroscience[13][14]
- 2010: Honorary fellow, University of Oxford Corpus Christi College
- 2009: Fellow, Academy of Medical Sciences[15]
- 2007: Fellow, Royal Society[16]
- 2006: Neuronal Plasticity Prize, Fondation IPSEN
- 2005: Outstanding Achievement Award, Neuroscience Division, Society of Chinese Bioscientists in America
- 2004: Fellow, American Association for the Advancement of Science
- 1999: Young Investigator Award, Society for Neuroscience
- 1995: Member, Society for Neuroscience
Selected publications
edit- Sheng, Morgan; Greenberg, Michael E. (1 April 1990). "The regulation and function of c-fos and other immediate early genes in the nervous system". Neuron. 4 (4). Cell Press: 477–485. doi:10.1016/0896-6273(90)90106-P. PMID 1969743. Retrieved 1 November 2023.
- Kim, Eunjoon; Sheng, Morgan (1 October 2004). "PDZ domain proteins of synapses". Nature Reviews Neuroscience. 5 (10): 771–781. doi:10.1038/nrn1517. PMID 15378037. Retrieved 1 November 2023.
- Sheng, Morgan; Thompson, Margaret A.; Greenberg, Michael E. (7 June 1991). "CREB: a Ca2+-Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases". Science. 252 (5011): 1427–1430. doi:10.1126/science.1646483. PMID 1646483. Retrieved 1 November 2023.
- Morgan, Sheng; Cummings, Jennifer; Roldan, Leslie Ann; Jan, Yuh Nung; Jan, Lily Yeh (10 March 1994). "Changing subunit composition of heteromeric NMDA receptors during development of rat cortex". Nature. 368 (6467). Nature Publishing Group UK: 144–147. doi:10.1038/368144a0. PMID 8139656. Retrieved 1 November 2023.
- Li, Zheng; Okamoto, Ken-Ichi; Hayashi, Yasunori; Sheng, Morgan (17 December 2004). "The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses". Cell. 119 (6). Elsevier: 873–887. doi:10.1016/j.cell.2004.11.003. PMID 15607982.
See also
editReferences
edit- ^ "Morgan Sheng, M.D., Ph.D." Broad Institute. 2 May 2019. Retrieved 1 November 2023.
- ^ "Morgan Sheng". Nature Reviews Drug Discovery. 8 (10): 766. 2009. doi:10.1038/nrd3014. PMID 19794439. Retrieved 1 November 2023.
- ^ "About". Broad Institute. Retrieved 1 November 2023.
- ^ "Strategic & Scientific Advisors". Cure Shark. Retrieved 1 November 2023.
- ^ "Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard". Vanqua Bio. Retrieved 1 November 2023.
- ^ "Morgan Sheng" (PDF). Cell. 27 June 2018. Retrieved 1 November 2023.
- ^ "Morgan Sheng". Nature Reviews Drug Discovery. 17 (2): 88–89. 19 January 2018. doi:10.1038/nrd.2017.271. PMID 29348680. Retrieved 1 November 2023.
- ^ "Morgan Sheng, Ph.D." Simons Foundation. 21 July 2017. Retrieved 1 November 2023.
- ^ "Morgan Sheng Appointed VP Neuroscience Research at Genentech". BioPharm. 8 October 2008. Retrieved 1 November 2023.
- ^ "Morgan Sheng". Picower Institute for Learning and Memory. Massachusetts Institute of Technology. Retrieved 1 November 2023.
- ^ "Twelve with MIT ties elected to the National Academy of Medicine for 2023". MIT News. Massachusetts Institute of Technology. 10 October 2023. Retrieved 1 November 2023.
- ^ "National Academy of Medicine Elects 100 New Members". National Academy of Sciences. 9 October 2023. Retrieved 1 November 2023.
- ^ Tristan Davies (27 October 2020). "Morgan Sheng wins Julius Axelrod Prize for distinguished achievements in neuropharmacology". Department of Brain and Cognitive Sciences. Massachusetts Institute of Technology. Retrieved 1 November 2023.
- ^ "Society for Neuroscience Presents Julius Axelrod Prize to Morgan Sheng". Society for Neuroscience. 26 October 2020. Retrieved 1 November 2023.
- ^ "Fellow: Professor Morgan Sheng FRS FMedSci". Academy of Medical Sciences. 2009. Retrieved 1 November 2023.
- ^ "Fellowship of the Royal Society 1660–2015". London: Royal Society. Archived from the original on 2015-10-15.