Pheneridine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine).[1]

Pheneridine
Clinical data
ATC code
  • none
Identifiers
  • Ethyl 4-phenyl-1-(2-phenylethyl)piperidine-4-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H27NO2
Molar mass337.463 g·mol−1
3D model (JSmol)
  • O=C(OCC)C3(c1ccccc1)CCN(CCc2ccccc2)CC3
  • InChI=1S/C22H27NO2/c1-2-25-21(24)22(20-11-7-4-8-12-20)14-17-23(18-15-22)16-13-19-9-5-3-6-10-19/h3-12H,2,13-18H2,1H3 checkY
  • Key:IUNKCJPURQMGKG-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Pheneridine is not currently used in medicine. Presumably it has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression, however unlike most opioid derivatives it is not specifically listed as an illegal drug, although it would probably be regarded as a controlled substance analogue of pethidine on the grounds of its related chemical structure in some jurisdictions such as the United States, Canada and Australia, and would be classified as a "Pethidine Analogue" under the New Zealand Misuse of Drugs Act Class C7.

See also

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References

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  1. ^ Janssen PA, Eddy NB (February 1960). "Compounds related to pethidine-IV. New general chemical methods of increasing the analgesic activity of pethidine". J Med Pharm Chem. 2: 31–45. doi:10.1021/jm50008a003. PMID 14406754.


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