Rosalind Anne Eeles is a Professor of Oncogenetics at the Institute of Cancer Research and clinician at the Royal Marsden NHS Foundation Trust. She is a leader in the field of genetic susceptibility to prostate cancer, and is known for the discovery of 14 genetic variants involved in prostate cancer predisposition.[1] According to ResearchGate, Eeles has published more than 500 articles in peer-reviewed journals, with over 34,000 citations and an h-index of 92.[2] Eeles was elected a Fellow of the Academy of Medical Science in 2012.[1] She was awarded a National Institute for Health Research Senior Investigator Emeritus in 2014.[3][4]
Rosalind Eeles | |
|---|---|
| Alma mater | |
| Scientific career | |
| Fields | Oncogenetics, Cancer genetics |
| Institutions | |
| Thesis | Germline and Somatic Mutations in the TP53 Gene in Breast and Other Cancers (2000) |
Education
editEeles completed her medical training at the University of Cambridge and St Thomas' Hospital Medical School, and trained in Clinical Oncology at The Royal Marsden NHS Foundation Trust.[5] She completed a PhD in cancer genetics at the Institute of Cancer Research, finishing her thesis in 2000.[6]
Research
editEeles' research is focussed on the genetic causes of prostate cancer and identifying patients with increased risk of developing the disease.[7] She leads a UK clinical trial investigating the impact of regular screening for patients with increased risk of prostate cancer due to BRCA mutations.[8] Eeles also established PRACTICAL, an international consortium that allows researchers to share genetic data from prostate cancer patients. Her research group are part of the International Cancer Genome Consortium (ICGC).[9]
Selected works
edit- Magali Olivier; Rosalind Eeles; Monica Hollstein; Mohammed A Khan; Curtis C Harris; Pierre Hainaut (1 June 2002). "The IARC TP53 database: new online mutation analysis and recommendations to users". Human Mutation. 19 (6): 607–614. doi:10.1002/HUMU.10081. ISSN 1059-7794. PMID 12007217. Wikidata Q43714274.
- Rosalind A Eeles; Zsofia Kote-Jarai; Graham G Giles; et al. (March 2008). "Multiple newly identified loci associated with prostate cancer susceptibility". Nature Genetics. 40 (3): 316–21. doi:10.1038/NG.90. ISSN 1061-4036. PMID 18264097. Wikidata Q28268180.
- Rosalind A Eeles; Zsofia Kote-Jarai; Ali Amin Al Olama; et al. (20 September 2009). "Identification of seven new prostate cancer susceptibility loci through a genome-wide association study". Nature Genetics. 41 (10): 1116–1121. doi:10.1038/NG.450. ISSN 1061-4036. PMC 2846760. PMID 19767753. Wikidata Q29417022.
{{cite journal}}:|author101=has generic name (help) - Mahbubl Ahmed; Chee Goh; Edward Saunders; Clara Cieza-Borrella; PRACTICAL consortium; Zsofia Kote-Jarai; Fredrick R Schumacher; Rosalind Eeles (27 November 2019). "Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT". Prostate Cancer and Prostatic Diseases. doi:10.1038/S41391-019-0181-Y. ISSN 1365-7852. PMID 31776447. Wikidata Q91496974.
- Elizabeth K. Bancroft; Kelly Kohut; Rosalind Eeles (3 February 2020). "The New Genomics Era: Integration of genomics into mainstream oncology and implications for psycho-oncological care". Psycho-Oncology. 29 (3): 453–460. doi:10.1002/PON.5331. ISSN 1057-9249. PMID 32017261. Wikidata Q89525325.
References
edit- ^ a b "Professor Rosalind Eeles | The Academy of Medical Sciences". acmedsci.ac.uk. Retrieved 23 May 2019.
- ^ "Ros Eeles". ResearchGate. Retrieved 24 May 2019.
- ^ "Senior Investigators". si.gmg-is.co.uk. Retrieved 24 May 2019.
- ^ "ORCID". orcid.org. Retrieved 24 May 2019.
- ^ "Prof. Ros Eeles - AcademiaNet". www.academia-net.org. Retrieved 24 May 2019.
- ^ Eeles, Rosalind Anne (2000). Germline and somatic studies in the TP53 gene in breast and other cancers (Ph.D. thesis). Institute of Cancer Research (University Of London).
- ^ "Professor Rosalind Eeles". Cancer Research UK. 15 March 2017. Retrieved 24 May 2019.
- ^ "The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer - Full Text View - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 24 May 2019.
- ^ "United Kingdom - Prostate Cancer |". icgc.org. Retrieved 24 May 2019.