Somatrem

Somatrem
Clinical data
Trade names	Protropin
AHFS/Drugs.com	Micromedex Detailed Consumer Information
ATC code	H01AC02 (WHO) ;
Identifiers
CAS Number	82030-87-3 ;
DrugBank	DB09098 ;
ChemSpider	none;
UNII	CU8D464EDW;
KEGG	D05884 ;
ChEMBL	ChEMBL1201620 ;
Chemical and physical data
Formula	C995H1537N263O301S8
Molar mass	22256.26 g·mol−1
	(what is this?) (verify)

Somatrem, sold under the brand name Protropin, is an analogue of growth hormone (GH).^[1]

Overview

Somatrem is a recombinant human growth hormone used for the treatment of short stature due to decreased or absent secretion of endogenous growth hormone.

Somatrem was first marketed under the brand name Protropin by Genentech in 1985.^[2] It differs from endogenous growth hormone by the addition of an extra methionine at the N-terminus^[3]^{[circular reference]}.

Somatrem has largely been replaced by somatropin, marketed by several companies including by Genentech as the brand Nutropin.

References

^ Flodh H (1987). "Present situation worldwide regarding the use and clinical experience of Somatonorm (somatrem)". Acta Paediatrica Scandinavica. Supplement. 331: 1–4. doi:10.1111/j.1651-2227.1987.tb17089.x. PMID 3300150. S2CID 20410776.
^ "Genentech: Press Releases - Friday, Oct 18, 1985". www.gene.com.
^ Growth hormone therapy#cite note-32

External links

"Somatrem". Drug Information Portal.
HyperGH 14x Growth Hormone Info.

This hormonal preparation article is a stub. You can help Wikipedia by expanding it.

[pmid3300150-1] Flodh H (1987). "Present situation worldwide regarding the use and clinical experience of Somatonorm (somatrem)". Acta Paediatrica Scandinavica. Supplement. 331: 1–4. doi:10.1111/j.1651-2227.1987.tb17089.x. PMID 3300150. S2CID 20410776.

[2] "Genentech: Press Releases - Friday, Oct 18, 1985". www.gene.com.

[3] Growth hormone therapy#cite note-32

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