Diamond Light Source: Difference between revisions

Content deleted Content added
No edit summary
Line 58:
* In November 2010 data collected at Diamond by [[Imperial College London]] formed the basis for a paper in the journal [[Nature (journal)|Nature]] advancing the understanding of how HIV and other retroviruses infect human and animal cells.<ref>[http://www.diamond.ac.uk/Home/Media/LatestNews/10_11_10.html Diamond News: X-rays illuminate the mechanism used by HIV to attack human DNA]</ref><ref>{{Cite journal | doi=10.1038/nature09517| pmid=21068843| pmc=2999894| title=The mechanism of retroviral integration from X-ray structures of its key intermediates| journal=Nature| volume=468| issue=7321| pages=326–329| year=2010| last1=Maertens| first1=Goedele N.| last2=Hare| first2=Stephen| last3=Cherepanov| first3=Peter| bibcode=2010Natur.468..326M}}</ref> The findings may enable improvements in gene therapy to correct gene malfunctions.
* In June 2011 data from Diamond led to an article in the journal Nature detailing the 3D structure of the human [[Histamine H1 receptor]] protein. This led to the development of 'third generation' [[Antihistamine|anti-histamines]], drugs effective against some allergies without adverse side-effects.<ref>[http://www.diamond.ac.uk/Home/Media/LatestNews/22_06_11.html Diamond News: Histamine H1 receptor breakthrough heralds improved allergy treatments]</ref><ref>{{cite journal | doi = 10.1038/nature10236 | pmid=21697825 | volume=475 | issue=7354 | title=Structure of the human histamine H1 receptor complex with doxepin | year=2011 | journal=Nature | pages=65–70 | last1 = Shimamura | first1 = Tatsuro| pmc=3131495 }}</ref>
* In December 2017, [[Diamond Light Source]], UK established the Synchrotron Techniques for African Research and Technology (START) with a £3.7 million funded by the [[UK Research and Innovation]] for 3 years. START aimed to provide access to African researchers with focus on energy materials and structural biology. The step is curcuial for the inception of the first [[The African Light Source|African Light Source]]. <ref>{{Cite web |title=GCRF - START: Synchrotron Techniques for African Research and Technology |url=https://gtr.ukri.org/projects?ref=ST%2FR002754%2F1}}</ref><ref>{{Cite journal |last1=Nicklin |first1=Chris |last2=Stredwick |first2=Rebekka |last3=Sewell |first3=Trevor |date=2022-01-02 |title=Synchrotron Techniques for African Research and Technology: A Step-Change in Structural Biology and Energy Materials |url=https://doi.org/10.1080/08940886.2022.2043684 |journal=Synchrotron Radiation News |volume=35 |issue=1 |pages=14–19 |bibcode=2022SRNew..35a..14N |doi=10.1080/08940886.2022.2043684 |issn=0894-0886 |s2cid=247431515}}</ref>
*Published in the [https://www.pnas.org/content/115/19/E4350 Proceedings of the National Academy of Sciences] in April 2018, a five institution collaboration including scientists from Diamond used three of Diamond's macromolecular beamlines to discover details of how a bacterium used plastic as an energy source. High resolution data allowed the researchers to determine the workings of an enzyme that degraded the plastic [[Polyethylene terephthalate|PET]]. Subsequently computational modelling was carried out to investigate and thus improve this mechanism.<ref>{{Cite web|url=https://www.diamond.ac.uk/Home/News/LatestNews/2018/16-04-2018.html|title=Solution to plastic pollution on the horizon - Diamond Light Source|last=Diamond Light Source|website=www.diamond.ac.uk|language=en|access-date=2019-10-05}}</ref>
*An article published in [https://www.nature.com/articles/s41929-019-0334-3 Nature] in 2019 described how a worldwide multidisciplinary collaboration designed several ways to control metal nano-particles, including synthesis at a substantially reduced cost for use as catalysts for the production of everyday goods.<ref>{{Cite web|url=https://www.diamond.ac.uk/Home/News/LatestNews/2019/30-09-2019.html|title=Worldwide scientific collaboration develops catalysis breakthrough - Diamond Light Source|website=www.diamond.ac.uk|access-date=2019-10-05}}</ref>
  NODES
innovation 1
Project 1
USERS 2