Talk:Diphenhydramine

Anxiety

I used Diphenhydramine for anxiety for a long time, and it works, although its not approved to treat Anxiety. Of course, this is an off label use, but it works. My friends also tell me how much it helped them, so I added a sub section under Medical uses for this. There are many other anti histamines, and they are meant to treat anxiety. For example Hydroxyzine. But Hydroxyzine requires a prescription, while Benadryl can be purchased without a prescription. A prescription can be difficult to get sometimes, and when you need something quick and easy to get to help you relax, Benadryl is a good temporary choice. I was hoping if somebody can please help improve the article by adding more details about Diphenhydramine's ability to help with Anxiety. It also has antidepressant properties, which is mentioned somewhere in the article, but there's not enough details it seems.

For now, I only added the anxiety sub section. Noam Atadgy (talk) 02:41, 8 November 2024 (UTC)

The sources you added are not reliable for medical content, WP:MEDRS, especially for treating a common disorder, such as anxiety. Your edit and explanation here were more about personal experience, which is WP:OR.

I rewrote the 'Anxiety' section with this edit. See that source with a specific explanation about the use of Benadryl for anxiety - it is not approved by the FDA, so should not be stated in the article as a common, clinically-valid use. Zefr (talk) 20:04, 9 November 2024 (UTC)

Okay looks fine to me, although there are sources which explicitly say people use it for anxiety, regardless of approval of any organization. How about instead we write something like,

"Diphenhydramine is also used to treat / help with Anxiety, but this is an off label use" ?

Its an off label use obviously. When people take Benadryl(Diphenhydramine) in the US for Anxiety, they do so in an off label way, off label use. Why cant we put it that way in the article too? Namelesss (talk) 09:16, 10 November 2024 (UTC)

Just to avoid confusion, I'm "Noam Atadgy", I just changed my name to Namelesss. Im the same person, hehe...

Do you know what off label use is? We should mention its used this way for Anxiety, in an off label way, no? Namelesss (talk) 09:20, 10 November 2024 (UTC)

@Namelesss Anxiety has extensive treatment guidlines and there is probably hundreds of medications that are used off-label for it. To mention this on every article would be WP:UNDUE in my opinion. IntentionallyDense (talk) 23:09, 10 November 2024 (UTC)

I was unable to find any WP:MEDRS reviews covering safe and effective off-label use for treating anxiety. These are the PubMed results. Zefr (talk) 23:36, 10 November 2024 (UTC)

Thanks I was too lazy to check this myself. I think this ultimately comes down to the fact that there is tons of medications used off label for anxiety and not all of them have the sourcing needed nor the weight needed to be included. IntentionallyDense (talk) 00:15, 11 November 2024 (UTC)

Nausea

About nausea, is Benadryl helping nausea same as Dramamine does,? So it has the same effect, same medication? Because in the article, it says can be used for Nausea, but Dimenhydrinate (Dramamine) is the one meant for that. Namelesss (talk) 09:23, 10 November 2024 (UTC)

@Namelesss Dimenhydrinate (Dramamine) is in the same class of medication as Diphenhydramine (Benadryl), they are both antihistamines meaning they work in similiar ways but are different medications. Both can be used for nausea. (sources:[1][2]). IntentionallyDense (talk) 23:12, 10 November 2024 (UTC)