The Great Silence is a 1968 an Italian-French Spaghetti Western directed and co-written by Sergio Corbucci.
The Great Silence may also refer to:
- The Great Silence: Science and Philosophy of Fermi's Paradox, a 2018 book by Milan M. Ćirković
- "The Great Silence" (short story), a 2015 short story by Ted Chiang
- Fermi paradox or the Great Silence, the seemingly paradoxical absence of evidence for extraterrestrial intelligence, named after Enrico Fermi
This disambiguation page lists articles associated with the title The Great Silence.
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