Ytterbium(III) chloride

Ytterbium(III) chloride
Names
	IUPAC name Ytterbium(III) chloride
Identifiers
CAS Number	10361-91-8 ; hydrate: 19423-87-1 ; 19423-82-6 (non-specific) ;
3D model (JSmol)	Interactive image;
ChemSpider	55430 ;
ECHA InfoCard	100.030.715
EC Number	233-800-5;
PubChem CID	9860484;
UNII	IO29D13DLW ;
CompTox Dashboard (EPA)	DTXSID0047117 ;
	InChI InChI=1S/3ClH.Yb/h31H;/q;;;+3/p-3 Key: CKLHRQNQYIJFFX-UHFFFAOYSA-K ; InChI=1/3ClH.Yb/h31H;/q;;;+3/p-3 Key: CKLHRQNQYIJFFX-DFZHHIFOAT;
	SMILES Cl[Yb](Cl)Cl;
Properties
Chemical formula	YbCl3
Molar mass	279.40 g/mol
Appearance	White powder
Density	4.06 g/cm3 (solid)
Melting point	854 °C (1,569 °F; 1,127 K)
Boiling point	1,453 °C (2,647 °F; 1,726 K)
Solubility in water	17 g/100 mL (25 °C)
Structure
Crystal structure	Monoclinic, mS16
Space group	C12/m1, No. 12
Related compounds
Other anions	Ytterbium(III) oxide
Other cations	Terbium(III) chloride, Lutetium(III) chloride
Supplementary data page
	Ytterbium(III) chloride (data page)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Ytterbium(III) chloride (Yb Cl₃) is an inorganic chemical compound. It reacts with NiCl₂ to form a very effective catalyst for the reductive dehalogenation of aryl halides.^[2] It is poisonous if injected, and mildly toxic by ingestion. It is an experimental teratogen, known to irritate the skin and eyes.

History

The synthesis of YbCl₃ was first reported by Jan Hoogschagen in 1946.^[3] It is now a commercially available source of Yb³⁺ ions and therefore of significant chemical interest.

Chemical properties

The valence electron configuration of Yb⁺³ (from YbCl₃) is 4f¹³5s²5p⁶, which has crucial implications for the chemical behaviour of Yb⁺³. Also, the size of Yb⁺³ governs its catalytic behaviour and biological applications. For example, while both Ce⁺³ and Yb⁺³ have a single unpaired f electron, Ce⁺³ is much larger than Yb⁺³ because lanthanides become much smaller with increasing effective nuclear charge as a consequence of the f electrons not being as well shielded as d electrons.^[4] This behavior is known as the lanthanide contraction. The small size of Yb⁺³ produces fast catalytic behavior and an atomic radius (0.99 Å) comparable to many biologically important ions.^[4]

The gas-phase thermodynamic properties of this chemical are difficult to determine because the chemical can disproportionate to form [YbCl₆]⁻³ or dimerize.^[5] The Yb₂Cl₆ species was detected by electron impact (EI) mass spectrometry as (Yb₂Cl₅⁺).^[5] Additional complications in obtaining experimental data arise from the myriad of low-lying f-d and f-f electronic transitions.^[6] Despite these issues, the thermodynamic properties of YbCl₃ have been obtained and the C_3V symmetry group has been assigned based upon the four active infrared vibrations.^[6]

Preparation

Anhydrous ytterbium(III) chloride can be produced by the ammonium chloride route.^[7]^[8]^[9] In the first step, ytterbium oxide is heated with ammonium chloride to produce the ammonium salt of the pentachloride:

Yb₂O₃ + 10 NH₄Cl → 2 (NH₄)₂YbCl₅ + 6 H₂O + 6 NH₃

In the second step, the ammonium chloride salt is converted to the trichlorides by heating in a vacuum at 350-400 °C:

(NH₄)₂YbCl₅ → YbCl₃ + 2 HCl + 2 NH₃

Reactions

YbCl₃ is a paramagnetic Lewis acid, like many of the lanthanide chlorides. It gives rise to pseudocontact shifted NMR spectra, akin to NMR shift reagents

Applications in biology

Membrane biology has been greatly influenced by YbCl₃, where³⁹K⁺ and²³Na⁺ ion movement is critical in establishing electrochemical gradients.^[10] Nerve signaling is a fundamental aspect of life that may be probed with YbCl₃ using NMR techniques. YbCl₃ may also be used as a calcium ion probe, in a fashion similar to a sodium ion probe.^[11]

YbCl₃ is also used to track digestion in animals. Certain additives to swine feed, such as probiotics, may be added to either solid feed or drinking liquids. YbCl₃ travels with the solid food and therefore helps determine which food phase is ideal to incorporate the food additive.^[12] The YbCl₃ concentration is quantified by inductively coupled plasma mass spectrometry to within 0.0009 μg/mL.^[4] YbCl₃ concentration versus time yields the flow rate of solid particulates in the animal's digestion. The animal is not harmed by the YbCl₃ since YbCl₃ is simply excreted in fecal matter and no change in body weight, organ weight, or hematocrit levels has been observed in mice.^[11]

The catalytic nature of YbCl₃ also has an application in DNA microarrays, or so called DNA “chips”.^[13] YbCl₃ led to a 50–80 fold increase in fluorescein incorporation into _target DNA, which could revolutionize infectious disease detection (such as a rapid test for tuberculosis).^[13]

References

^ ^a ^b Walter Benenson; John W. Harris; Horst Stöcker (2002). Handbook of Physics. Springer. p. 781. ISBN 0-387-95269-1.
^ Zhang, Yuankui; Liao, Shijian; Xu, Yun; Yu, Daorong; Shen, Qi (1997). "Reductive Dehalogenation of Aryl Halides by the Nanometric Sodium Hydride Using Lanthanide Chloride as Catalyst". Synth. Commun. 27 (24): 4327–4334. doi:10.1080/00397919708005057.
^ Hoogschagen, J. (1946). "The light absorption in the near infra red region of praseodymium, samarium and ytterbium solutions". Physica. 11 (6): 513–517. Bibcode:1946Phy....11..513H. doi:10.1016/S0031-8914(46)80020-X.
^ ^a ^b ^c Evans, C.H. (1990). Biochemistry of the Lanthanides. New York: Plenum. ISBN 978-1-4684-8750-3.
^ ^a ^b Chervonnyi, A.D.; Chervonnaya, N.A. (2004). "Thermodynamic Properties of Ytterbium Chlorides". Russ. J. Inorg. Chem. (Engl. Transl.). 49 (12): 1889–1897.
^ ^a ^b Zasorin, E. Z. (1988). "Structure of the rare-earth element trihalide molecules from electron diffraction and spectral data". Russ. J. Phys. Chem. (Engl. Transl.). 62 (4): 441–447. (Russian language version: Zh. Fiz. Khim. 62(4), pp. 883-895)
^ Brauer, G., ed. (1963). Handbook of Preparative Inorganic Chemistry (2nd ed.). New York: Academic Press.
^ Meyer, G. (1989). "The Ammonium Chloride Route to Anhydrous Rare Earth Chlorides—The Example of Ycl ₃". The Ammonium Chloride Route to Anhydrous Rare Earth Chlorides-The Example of YCl₃. Inorganic Syntheses. Vol. 25. pp. 146–150. doi:10.1002/9780470132562.ch35. ISBN 978-0-470-13256-2.
^ Edelmann, F. T.; Poremba, P. (1997). Herrmann, W. A. (ed.). Synthetic Methods of Organometallic and Inorganic Chemistry. Vol. VI. Stuttgart: Georg Thieme Verlag. ISBN 978-3-13-103021-4.
^ Hayer, M.K.; Riddell, F.G. (1984). "Shift reagents for ³⁹K NMR". Inorganica Chimica Acta. 92 (4): L37 – L39. doi:10.1016/S0020-1693(00)80044-4.
^ ^a ^b Shinohara, A.; Chiba, M.; Inaba, Y. (2006). "Comparative study of the behavior of terbium, samarium, and ytterbium intravenously administered in mice". Journal of Alloys and Compounds. 408–412: 405–408. doi:10.1016/j.jallcom.2004.12.152.
^ Ohashi, Y.; Umesaki, Y.; Ushida, K. (2004). "Transition of the probiotic bacteria, Lactobacillus casei strain Shirota, in the gastrointestinal tract of a pig". International Journal of Food Microbiology. 96 (1): 61–66. doi:10.1016/j.ijfoodmicro.2004.04.001. PMID 15358506.
^ ^a ^b Browne, K.A. (2002). "Metal ion-catalyzed nucleic acid alkylation and fragmentation". Journal of the American Chemical Society. 124 (27): 7950–7962. doi:10.1021/ja017746x. PMID 12095339.

[melt-1] Walter Benenson; John W. Harris; Horst Stöcker (2002). Handbook of Physics. Springer. p. 781. ISBN 0-387-95269-1.

[2] Zhang, Yuankui; Liao, Shijian; Xu, Yun; Yu, Daorong; Shen, Qi (1997). "Reductive Dehalogenation of Aryl Halides by the Nanometric Sodium Hydride Using Lanthanide Chloride as Catalyst". Synth. Commun. 27 (24): 4327–4334. doi:10.1080/00397919708005057.

[r2-3] Hoogschagen, J. (1946). "The light absorption in the near infra red region of praseodymium, samarium and ytterbium solutions". Physica. 11 (6): 513–517. Bibcode:1946Phy....11..513H. doi:10.1016/S0031-8914(46)80020-X.

[ref1-4] Evans, C.H. (1990). Biochemistry of the Lanthanides. New York: Plenum. ISBN 978-1-4684-8750-3.

[ref4-5] Chervonnyi, A.D.; Chervonnaya, N.A. (2004). "Thermodynamic Properties of Ytterbium Chlorides". Russ. J. Inorg. Chem. (Engl. Transl.). 49 (12): 1889–1897.

[ref5-6] Zasorin, E. Z. (1988). "Structure of the rare-earth element trihalide molecules from electron diffraction and spectral data". Russ. J. Phys. Chem. (Engl. Transl.). 62 (4): 441–447. (Russian language version: Zh. Fiz. Khim. 62(4), pp. 883-895)

[Brauer-7] Brauer, G., ed. (1963). Handbook of Preparative Inorganic Chemistry (2nd ed.). New York: Academic Press.

[IS-8] Meyer, G. (1989). "The Ammonium Chloride Route to Anhydrous Rare Earth Chlorides—The Example of Ycl ₃". The Ammonium Chloride Route to Anhydrous Rare Earth Chlorides-The Example of YCl₃. Inorganic Syntheses. Vol. 25. pp. 146–150. doi:10.1002/9780470132562.ch35. ISBN 978-0-470-13256-2.

[EdelmannPoremba1997-9] Edelmann, F. T.; Poremba, P. (1997). Herrmann, W. A. (ed.). Synthetic Methods of Organometallic and Inorganic Chemistry. Vol. VI. Stuttgart: Georg Thieme Verlag. ISBN 978-3-13-103021-4.

[ref11-10] Hayer, M.K.; Riddell, F.G. (1984). "Shift reagents for ³⁹K NMR". Inorganica Chimica Acta. 92 (4): L37 – L39. doi:10.1016/S0020-1693(00)80044-4.

[ref12-11] Shinohara, A.; Chiba, M.; Inaba, Y. (2006). "Comparative study of the behavior of terbium, samarium, and ytterbium intravenously administered in mice". Journal of Alloys and Compounds. 408–412: 405–408. doi:10.1016/j.jallcom.2004.12.152.

[r13-12] Ohashi, Y.; Umesaki, Y.; Ushida, K. (2004). "Transition of the probiotic bacteria, Lactobacillus casei strain Shirota, in the gastrointestinal tract of a pig". International Journal of Food Microbiology. 96 (1): 61–66. doi:10.1016/j.ijfoodmicro.2004.04.001. PMID 15358506.

[ref14-13] Browne, K.A. (2002). "Metal ion-catalyzed nucleic acid alkylation and fragmentation". Journal of the American Chemical Society. 124 (27): 7950–7962. doi:10.1021/ja017746x. PMID 12095339.

[2]

[1]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]