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Etymology

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Attested 1963; from opium +‎ -oid, to distinguish from opiate.

Pronunciation

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Noun

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opioid (plural opioids)

  1. A substance that has effects similar to opium:
    1. (physiology) Any of the natural substances, such as an endorphin, released in the body in response to pain; an endogenous opioid.
    2. (pharmacology) Any of a group of synthetic compounds that exhibit similarities to the opium alkaloids that occur in nature.
      Hyponym: opiate

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